Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Outer surface protein B

Gene

ospB

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Outer surface protein B
Gene namesi
Name:ospB
Ordered Locus Names:BB_A16
Encoded oniPlasmid lp540 Publication
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Plasmid lp54

Subcellular locationi

GO - Cellular componenti

  • cell outer membrane Source: UniProtKB-SubCell
  • membrane Source: CAFA

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Add BLAST15
ChainiPRO_000001808116 – 296Outer surface protein BAdd BLAST281

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi16N-palmitoyl cysteineCurated1
Lipidationi16S-diacylglycerol cysteineCurated1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PRIDEiP17739

Interactioni

Protein-protein interaction databases

DIPiDIP-60765N
IntActiP17739, 1 interactor

Structurei

Secondary structure

1296
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi158 – 161Combined sources4
Beta strandi167 – 177Combined sources11
Beta strandi179 – 186Combined sources8
Helixi187 – 189Combined sources3
Beta strandi190 – 197Combined sources8
Beta strandi200 – 207Combined sources8
Beta strandi210 – 216Combined sources7
Beta strandi218 – 228Combined sources11
Beta strandi231 – 233Combined sources3
Beta strandi235 – 240Combined sources6
Helixi241 – 243Combined sources3
Beta strandi245 – 250Combined sources6
Beta strandi253 – 260Combined sources8
Beta strandi266 – 271Combined sources6
Beta strandi275 – 278Combined sources4
Helixi288 – 294Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P4PX-ray2.00A152-296[»]
1RJLX-ray2.60C202-296[»]
ProteinModelPortaliP17739
SMRiP17739
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP17739

Family & Domainsi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR001809 OM_lipoprot_Borrelia
IPR023322 OM_lipoprot_dom_sf
PfamiView protein in Pfam
PF00820 Lipoprotein_1, 1 hit
PRINTSiPR00968 OUTRSURFACE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001127 OM_lipoprot_Borrelia, 1 hit
SUPFAMiSSF51087 SSF51087, 1 hit
PROSITEiView protein in PROSITE
PS51257 PROKAR_LIPOPROTEIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17739-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLIGFALA LALIGCAQKG AESIGSQKEN DLNLEDSSKK SHQNAKQDLP
60 70 80 90 100
AVTEDSVSLF NGNKIFVSKE KNSSGKYDLR ATIDQVELKG TSDKNNGSGT
110 120 130 140 150
LEGSKPDKSK VKLTVSADLN TVTLEAFDAS NQKISSKVTK KQGSITEETL
160 170 180 190 200
KANKLDSKKL TRSNGTTLEY SQITDADNAT KAVETLKNSI KLEGSLVGGK
210 220 230 240 250
TTVEIKEGTV TLKREIEKDG KVKVFLNDTA GSNKKTGKWE DSTSTLTISA
260 270 280 290
DSKKTKDLVF LTDGTITVQQ YNTAGTSLEG SASEIKNLSE LKNALK
Length:296
Mass (Da):31,733
Last modified:April 18, 2012 - v2
Checksum:i4B54CBABC39880A5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12A → R in AAA63758 (PubMed:7513309).Curated1
Sequence conflicti198G → V in CAA32580 (PubMed:2761388).Curated1
Sequence conflicti214R → I in AAA63758 (PubMed:7513309).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti42H → Y in strain: CA7. 1
Natural varianti89K → R in strain: 41552MA. 1
Natural varianti123T → S in strain: CA8. 1
Natural varianti126A → T in strain: 21343WI, 41552MA, 42373NY3, HB19 and HB19CT1. 1
Natural varianti128D → N in strain: 21343WI, 41552MA, HB19 and HB19CT1. 1
Natural varianti132Q → P in strain: CA8. 1
Natural varianti176A → T in strain: CA8. 1
Natural varianti189S → G in strain: CA8. 1
Natural varianti192L → F in strain: CA8. 1
Natural varianti198G → V in strain: 21343WI, CA3 and CA7. 1
Natural varianti218K → Q in strain: CA8. 1
Natural varianti253K → T in strain: 21343WI, 41552MA, 42373NY3, HB19 and HB19CT1. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X14407 Genomic DNA Translation: CAA32580.1
L23136 Genomic DNA Translation: AAA22952.1
L23137 Genomic DNA Translation: AAA22954.1
L23138 Genomic DNA Translation: AAA20948.1
L23139 Genomic DNA Translation: AAA20950.1
L23140 Genomic DNA Translation: AAA20952.1
L23141 Genomic DNA Translation: AAA20954.1
L23142 Genomic DNA Translation: AAA20956.1
L23143 Genomic DNA Translation: AAA20958.1
L23144 Genomic DNA Translation: AAA20960.1
L31399 Genomic DNA Translation: AAA63758.1
AE000790 Genomic DNA Translation: AAC66243.2
PIRiH70208
I40250
I40252
I40256
I40258
I40260
I40264
I40266
I40267
S06915
RefSeqiNP_045689.2, NC_001857.2
WP_010890379.1, NC_001857.2

Genome annotation databases

EnsemblBacteriaiAAC66243; AAC66243; BB_A16
GeneIDi1194340
KEGGibbu:BB_A16
PATRICifig|224326.49.peg.1534

Similar proteinsi

Entry informationi

Entry nameiOSPB_BORBU
AccessioniPrimary (citable) accession number: P17739
Secondary accession number(s): O50909
, Q44963, Q44965, Q44966, Q44968, Q44970, Q44972, Q44975, Q57510
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: April 18, 2012
Last modified: April 25, 2018
This is version 120 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Plasmid, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health