##gff-version 3
P17710	UniProtKB	Chain	1	974	.	.	.	ID=PRO_0000013399;Note=Hexokinase-1	
P17710	UniProtKB	Domain	72	514	.	.	.	Note=Hexokinase 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Domain	520	962	.	.	.	Note=Hexokinase 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Region	1	42	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P17710	UniProtKB	Region	57	66	.	.	.	Note=Mitochondrial-binding peptide (MBP);Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Region	129	263	.	.	.	Note=Hexokinase small subdomain 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Region	264	503	.	.	.	Note=Hexokinase large subdomain 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Region	577	711	.	.	.	Note=Hexokinase small subdomain 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Region	712	951	.	.	.	Note=Hexokinase large subdomain 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01084	
P17710	UniProtKB	Binding site	86	86	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	140	147	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	140	145	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	211	211	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	228	229	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	264	265	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	265	265	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	288	288	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	291	291	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	316	316	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	347	350	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	469	471	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	481	482	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	505	505	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	588	593	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	588	592	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	659	660	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	676	677	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	712	713	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	713	713	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	736	736	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	736	736	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	738	739	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	764	764	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	798	798	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	803	804	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	840	844	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	917	919	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	919	923	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Binding site	953	953	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19367	
P17710	UniProtKB	Modified residue	393	393	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05708	
P17710	UniProtKB	Alternative sequence	1	76	.	.	.	ID=VSP_007327;Note=In isoform HK1. MGWGAPLLSRMLHGPGQAGETSPVPERQSGSENPASEDRRPLEKQCSHHLYTMGQNCQRGQAVDVEPKIRPPLTEE->MIAAQLLAYYFTELKDDQVK;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:2318862;Dbxref=PMID:2318862	
P17710	UniProtKB	Alternative sequence	1	52	.	.	.	ID=VSP_018747;Note=In isoform HK1-SB and isoform HK1-SC. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:8396993;Dbxref=PMID:8396993	
P17710	UniProtKB	Alternative sequence	400	400	.	.	.	ID=VSP_007328;Note=In isoform HK1-SB. T->TGWELSPDRRWYQAYMRCTQDTHR;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:8396993;Dbxref=PMID:8396993	
P17710	UniProtKB	Mutagenesis	67	67	.	.	.	Note=Disrupts targeting to membrane%3B when associated with N-68%3B Q-70%3B P-73%3B A-74 and Q-75. P->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Mutagenesis	68	68	.	.	.	Note=Disrupts targeting to membrane%3B when associated with A-67%3B Q-70%3B P-73%3B A-74 and Q-75. K->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Mutagenesis	70	70	.	.	.	Note=Disrupts targeting to membrane%3B when associated with A-67%3B N-68%3B P-73%3B A-74 and Q-75. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Mutagenesis	73	73	.	.	.	Note=Disrupts targeting to membrane%3B when associated with A-67%3B N-68%3B Q-70%3B A-74 and Q-75. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Mutagenesis	74	74	.	.	.	Note=Disrupts targeting to membrane%3B when associated with A-67%3B N-68%3B Q-70%3B P-73 and Q-75. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Mutagenesis	75	75	.	.	.	Note=Disrupts targeting to membrane%3B when associated with A-67%3B N-68%3B Q-70%3B P-73 and A-74. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10567428;Dbxref=PMID:10567428	
P17710	UniProtKB	Sequence conflict	870	870	.	.	.	Note=D->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P17710	UniProtKB	Sequence conflict	899	899	.	.	.	Note=E->Q;Ontology_term=ECO:0000305;evidence=ECO:0000305