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Protein

40S ribosomal protein S17

Gene

RpS17

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: FlyBase

GO - Biological processi

  • cytoplasmic translation Source: FlyBase
  • ribosomal small subunit assembly Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S17
Gene namesi
Name:RpS17
Synonyms:M(3)67C
ORF Names:CG3922
OrganismiDrosophila melanogaster (Fruit fly)
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 3L

Organism-specific databases

FlyBaseiFBgn0005533. RpS17.

Subcellular locationi

GO - Cellular componenti

  • cytosolic ribosome Source: FlyBase
  • cytosolic small ribosomal subunit Source: GO_Central
  • ribosome Source: FlyBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001415332 – 13140S ribosomal protein S17Add BLAST130

Proteomic databases

PaxDbiP17704.
PRIDEiP17704.

Expressioni

Gene expression databases

BgeeiFBgn0005533.
GenevisibleiP17704. DM.

Interactioni

Protein-protein interaction databases

BioGridi64481. 23 interactors.
DIPiDIP-20075N.
IntActiP17704. 16 interactors.
MINTiMINT-873330.
STRINGi7227.FBpp0076207.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AR1-131[»]
ProteinModelPortaliP17704.
SMRiP17704.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S17e family.Curated

Phylogenomic databases

eggNOGiKOG0187. Eukaryota.
COG1383. LUCA.
GeneTreeiENSGT00390000006548.
InParanoidiP17704.
KOiK02962.
OMAiVGMNFRT.
OrthoDBiEOG091G0TNU.
PhylomeDBiP17704.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e. 1 hit.
InterProiIPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiPF00833. Ribosomal_S17e. 1 hit.
[Graphical view]
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17704-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRVRTKTVK KAAKVIIEKY YTRLTLDFHT NKRICEEVAI IPTKPLRNKI
60 70 80 90 100
AGYVTHLMGR LRHSQVRGIS IKLQEEERER RDNYVPAVSA LEQDIIEVDA
110 120 130
DTKEMLKLLD FHNIRGLQLT QPNTNNFGRR N
Length:131
Mass (Da):15,285
Last modified:January 23, 2007 - v2
Checksum:i8EA8D7054A153DF2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M22142 Genomic DNA. Translation: AAA28869.1.
AE014296 Genomic DNA. Translation: AAF50272.1.
AJ271817 Genomic DNA. Translation: CAB72251.1.
BT001651 mRNA. Translation: AAN71406.1.
PIRiJU0055. R4FF17.
RefSeqiNP_524002.1. NM_079278.3.
UniGeneiDm.5973.

Genome annotation databases

EnsemblMetazoaiFBtr0076479; FBpp0076207; FBgn0005533.
GeneIDi39088.
KEGGidme:Dmel_CG3922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M22142 Genomic DNA. Translation: AAA28869.1.
AE014296 Genomic DNA. Translation: AAF50272.1.
AJ271817 Genomic DNA. Translation: CAB72251.1.
BT001651 mRNA. Translation: AAN71406.1.
PIRiJU0055. R4FF17.
RefSeqiNP_524002.1. NM_079278.3.
UniGeneiDm.5973.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4V6Welectron microscopy6.00AR1-131[»]
ProteinModelPortaliP17704.
SMRiP17704.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi64481. 23 interactors.
DIPiDIP-20075N.
IntActiP17704. 16 interactors.
MINTiMINT-873330.
STRINGi7227.FBpp0076207.

Proteomic databases

PaxDbiP17704.
PRIDEiP17704.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0076479; FBpp0076207; FBgn0005533.
GeneIDi39088.
KEGGidme:Dmel_CG3922.

Organism-specific databases

CTDi6218.
FlyBaseiFBgn0005533. RpS17.

Phylogenomic databases

eggNOGiKOG0187. Eukaryota.
COG1383. LUCA.
GeneTreeiENSGT00390000006548.
InParanoidiP17704.
KOiK02962.
OMAiVGMNFRT.
OrthoDBiEOG091G0TNU.
PhylomeDBiP17704.

Enzyme and pathway databases

ReactomeiR-DME-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DME-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DME-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-DME-72649. Translation initiation complex formation.
R-DME-72689. Formation of a pool of free 40S subunits.
R-DME-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-DME-72702. Ribosomal scanning and start codon recognition.
R-DME-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DME-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DME-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

ChiTaRSiRpS17. fly.
GenomeRNAii39088.
PROiP17704.

Gene expression databases

BgeeiFBgn0005533.
GenevisibleiP17704. DM.

Family and domain databases

Gene3Di1.10.60.20. 1 hit.
HAMAPiMF_00511. Ribosomal_S17e. 1 hit.
InterProiIPR001210. Ribosomal_S17e.
IPR018273. Ribosomal_S17e_CS.
[Graphical view]
PANTHERiPTHR10732. PTHR10732. 1 hit.
PfamiPF00833. Ribosomal_S17e. 1 hit.
[Graphical view]
SUPFAMiSSF116820. SSF116820. 1 hit.
PROSITEiPS00712. RIBOSOMAL_S17E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS17_DROME
AccessioniPrimary (citable) accession number: P17704
Secondary accession number(s): Q9V3P5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 127 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Ribosomal proteins
    Ribosomal proteins families and list of entries
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.