Reviewed, UniProtKB/Swiss-Prot P17598 (CATA1_GOSHI)

Names and origin

Protein names

Recommended name:
    Catalase isozyme 1
    EC=1.11.1.6

Gene names

Name:	CAT1
Synonyms:	SU1

Organism

Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)

Taxonomic identifier

3635 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Malvales › Malvaceae › Malvoideae › Gossypium

Protein attributes

Sequence length	492 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Subunit structure	Homotetramer.
Subcellular location	Peroxisome.
Miscellaneous	There are at least five isozymes of catalase in cotton.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Cellular component	Peroxisome
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	peroxisome Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 492	492	Catalase isozyme 1		PRO_0000084938
Sites
	Active site	65	1	By similarity
	Active site	138	1	By similarity
	Metal binding	348	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P17598-1 [UniParc]. Last modified February 1, 1996. Version 2. Checksum: 64886966A095F261	FASTA	492	56,855
	10 20 30 40 50 60 MDPYKHRPSS AFNSPFWTTN SGAPVWNNNS SLTVGPRGQY LLEDYHLVEK LANFDRERIP 70 80 90 100 110 120 ERVVHARGAS AKGFFEVTHD ISHLTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR 130 140 150 160 170 180 GFAVKFYTRE GNFDLVGNNF PVFFIRDGMK FPDMVHALKP NPKSHIQENW RILDFFSHHP 190 200 210 220 230 240 ESLHMFTFLF DDLGVPQDYR HMEGSGVNTY TLINKAGKAH YVKFHWKPTC GVKCLLEDEA 250 260 270 280 290 300 IKVGGANHSH ATQDLYDSIA AGNYPEWKLF IQTIDPDHED KFDFDPLDVT KTWPEDILPL 310 320 330 340 350 360 QPVGRLVLNK NIDNFFAENE QLAFCPAIVV PGIYYSDDKL LQTRIFSYSD TQRHRLGPNY 370 380 390 400 410 420 LQLPANAPKC AHHNNHHEGF MNFMHRDEEI NYFPSRYDPV RHAEMFPIPP AVCTGRREKC 430 440 450 460 470 480 IIEKENNFKQ PGERYRSWAA DRQERFICRW VDALSDPRVT HEIRSIWISY WSQADKSVGQ 490 KLASLLNVRP SI

References

[1]	"Characterization of a cDNA encoding cottonseed catalase." Ni W., Turley R.B., Trelease R.N. Biochim. Biophys. Acta 1049:219-222(1990) [PubMed: 2364113] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Deltapine 62. Tissue: Cotyledon.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X52135 mRNA. Translation: CAA36380.1.
PIR	S10395. S10770.
3D structure databases
HSSP	HSSP built from PDB template 1M7S based on UniProtKB P46206.
ModBase	Search...
Protein family/group databases
PeroxiBase	437. GhKat01.
Enzyme and pathway databases
BRENDA	1.11.1.6. 1857.
Family and domain databases
InterPro	IPR002226. Catalase. IPR010582. Catalase-rel_immune_responsive. IPR011614. Catalase_N. IPR018028. Catalase_rel_subgroup. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA1_GOSHI

Accession

Primary (citable) accession number: P17598

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	February 1, 1996
Last modified:	June 16, 2009
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)