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Protein

Aminoglycoside 6-adenylyltransferase

Gene

aadK

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciBSUB:BSU26790-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Aminoglycoside 6-adenylyltransferase (EC:2.7.7.-)
Alternative name(s):
AAD(6)
Gene namesi
Name:aadK
Ordered Locus Names:BSU26790
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284Aminoglycoside 6-adenylyltransferasePRO_0000064415Add
BLAST

Proteomic databases

PaxDbiP17585.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100014646.

Structurei

Secondary structure

1
284
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi4 – 1714Combined sources
Beta strandi21 – 266Combined sources
Beta strandi43 – 508Combined sources
Helixi52 – 565Combined sources
Helixi60 – 656Combined sources
Beta strandi68 – 725Combined sources
Beta strandi78 – 803Combined sources
Beta strandi88 – 947Combined sources
Beta strandi99 – 1068Combined sources
Helixi107 – 1093Combined sources
Helixi110 – 1156Combined sources
Beta strandi123 – 1286Combined sources
Helixi139 – 1413Combined sources
Helixi149 – 17123Combined sources
Helixi175 – 18410Combined sources
Helixi186 – 20217Combined sources
Beta strandi205 – 2073Combined sources
Helixi210 – 2123Combined sources
Helixi215 – 2173Combined sources
Helixi221 – 2288Combined sources
Helixi236 – 26126Combined sources
Helixi268 – 28114Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2PBEX-ray2.65A2-284[»]
ProteinModelPortaliP17585.
SMRiP17585. Positions 1-282.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP17585.

Family & Domainsi

Sequence similaritiesi

To E.faecalis AadE.Curated

Phylogenomic databases

eggNOGiENOG41075D4. Bacteria.
ENOG410YSKJ. LUCA.
HOGENOMiHOG000088252.
KOiK05593.
OMAiNQIVRHE.
OrthoDBiEOG65J50G.

Family and domain databases

InterProiIPR007530. Aminoglycoside_adenylylTfrase.
[Graphical view]
PfamiPF04439. Adenyl_transf. 1 hit.
[Graphical view]
PIRSFiPIRSF000812. AAD. 1 hit.

Sequencei

Sequence statusi: Complete.

P17585-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSEQEMMDI FLDFALNDER IRLVTLEGSR TNRNIPPDNF QDYDISYFVT
60 70 80 90 100
DVESFKENDQ WLEIFGKRIM MQKPEDMELF PPELGNWFSY IILFEDGNKL
110 120 130 140 150
DLTLIPIREA EDYFANNDGL VKVLLDKDSF INYKVTPNDR QYWIKRPTAR
160 170 180 190 200
EFDDCCNEFW MVSTYVVKGL ARNEILFAID HLNEIVRPNL LRMMAWHIAS
210 220 230 240 250
QKGYSFSMGK NYKFMKRYLS NKEWEELMST YSVNGYQEMW KSLFTCYALF
260 270 280
RKYSKAVSEG LAYKYPDYDE GITKYTEGIY CSVK
Length:284
Mass (Da):33,908
Last modified:August 1, 1990 - v1
Checksum:i69C970810B914F9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26879 Genomic DNA. Translation: AAA22190.1.
U93875 Genomic DNA. Translation: AAB80892.1.
U93876 Genomic DNA. Translation: AAB80893.1.
AL009126 Genomic DNA. Translation: CAB14620.1.
PIRiJU0059. XXBSG.
RefSeqiNP_390556.1. NC_000964.3.
WP_003229862.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14620; CAB14620; BSU26790.
GeneIDi938061.
KEGGibsu:BSU26790.
PATRICi18977204. VBIBacSub10457_2791.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26879 Genomic DNA. Translation: AAA22190.1.
U93875 Genomic DNA. Translation: AAB80892.1.
U93876 Genomic DNA. Translation: AAB80893.1.
AL009126 Genomic DNA. Translation: CAB14620.1.
PIRiJU0059. XXBSG.
RefSeqiNP_390556.1. NC_000964.3.
WP_003229862.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2PBEX-ray2.65A2-284[»]
ProteinModelPortaliP17585.
SMRiP17585. Positions 1-282.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100014646.

Proteomic databases

PaxDbiP17585.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14620; CAB14620; BSU26790.
GeneIDi938061.
KEGGibsu:BSU26790.
PATRICi18977204. VBIBacSub10457_2791.

Phylogenomic databases

eggNOGiENOG41075D4. Bacteria.
ENOG410YSKJ. LUCA.
HOGENOMiHOG000088252.
KOiK05593.
OMAiNQIVRHE.
OrthoDBiEOG65J50G.

Enzyme and pathway databases

BioCyciBSUB:BSU26790-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP17585.

Family and domain databases

InterProiIPR007530. Aminoglycoside_adenylylTfrase.
[Graphical view]
PfamiPF04439. Adenyl_transf. 1 hit.
[Graphical view]
PIRSFiPIRSF000812. AAD. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence of the chromosomal gene coding for the aminoglycoside 6-adenylyltransferase from Bacillus subtilis Marburg 168."
    Ohmiya K., Tanaka T., Noguchi N., O'Hara K., Kono M.
    Gene 78:377-378(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "Sequence of the Bacillus subtilis genome region in the vicinity of the lev operon reveals two new extracytoplasmic function RNA polymerase sigma factors SigV and SigZ."
    Sorokin A., Bolotin A., Purnelle B., Hilbert H., Lauber J., Duesterhoeft A., Ehrlich S.D.
    Microbiology 143:2939-2943(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiAADK_BACSU
AccessioniPrimary (citable) accession number: P17585
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: February 17, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.