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Protein

Cyanate transport protein CynX

Gene

cynX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This protein is part of an active transport system that transports exogenous cyanate into E.coli cells.

GO - Biological processi

  • cyanate catabolic process Source: EcoCyc
  • transmembrane transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:CYNX-MONOMER.
ECOL316407:JW0332-MONOMER.

Protein family/group databases

TCDBi2.A.1.17.1. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Cyanate transport protein CynX
Gene namesi
Name:cynX
Ordered Locus Names:b0341, JW0332
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10177. cynX.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei3 – 2321HelicalSequence analysisAdd
BLAST
Transmembranei34 – 5421HelicalSequence analysisAdd
BLAST
Transmembranei68 – 8821HelicalSequence analysisAdd
BLAST
Transmembranei89 – 10921HelicalSequence analysisAdd
BLAST
Transmembranei122 – 14221HelicalSequence analysisAdd
BLAST
Transmembranei153 – 17321HelicalSequence analysisAdd
BLAST
Transmembranei204 – 22421HelicalSequence analysisAdd
BLAST
Transmembranei235 – 25521HelicalSequence analysisAdd
BLAST
Transmembranei263 – 28321HelicalSequence analysisAdd
BLAST
Transmembranei287 – 30721HelicalSequence analysisAdd
BLAST
Transmembranei322 – 34221HelicalSequence analysisAdd
BLAST
Transmembranei354 – 37421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 384384Cyanate transport protein CynXPRO_0000205707Add
BLAST

Proteomic databases

PaxDbiP17583.

Interactioni

Protein-protein interaction databases

BioGridi4263183. 8 interactions.
STRINGi511145.b0341.

Structurei

3D structure databases

ProteinModelPortaliP17583.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJ2. Bacteria.
COG2807. LUCA.
HOGENOMiHOG000273879.
InParanoidiP17583.
KOiK03449.
OMAiGYIMGGF.
PhylomeDBiP17583.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004747. Cyan_transport.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00896. CynX. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P17583-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLVLVLIGL NMRPLLTSVG PLLPQLRQAS GMSFSVAALL TALPVVTMGG
60 70 80 90 100
LALAGSWLHQ HVSERRSVAI SLLLIAVGAL MRELYPQSAL LLSSALLGGV
110 120 130 140 150
GIGIIQAVMP SVIKRRFQQR TPLVMGLWSA ALMGGGGLGA AITPWLVQHS
160 170 180 190 200
ETWYQTLAWW ALPAVVALFA WWWQSAREVA SSHKTTTTPV RVVFTPRAWT
210 220 230 240 250
LGVYFGLING GYASLIAWLP AFYIEIGASA QYSGSLLALM TLGQAAGALL
260 270 280 290 300
MPAMARHQDR RKLLMLALVL QLVGFCGFIW LPMQLPVLWA MVCGLGLGGA
310 320 330 340 350
FPLCLLLALD HSVQPAIAGK LVAFMQGIGF IIAGLAPWFS GVLRSISGNY
360 370 380
LMDWAFHALC VVGLMIITLR FAPVRFPQLW VKEA
Length:384
Mass (Da):41,361
Last modified:November 1, 1997 - v2
Checksum:i05A579C7988E90A7
GO

Sequence cautioni

The sequence AAB18065 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271R → A in AAA23627 (PubMed:3049588).Curated
Sequence conflicti336 – 38449APWFS…WVKEA → PRGFLACCVVSAAIT (PubMed:3049588).CuratedAdd
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23219 Genomic DNA. Translation: AAA23627.1.
U73857 Genomic DNA. Translation: AAB18065.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73444.1.
AP009048 Genomic DNA. Translation: BAE76123.1.
PIRiE64761. BVECCX.
RefSeqiNP_414875.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC73444; AAC73444; b0341.
BAE76123; BAE76123; BAE76123.
GeneIDi946770.
KEGGiecj:JW0332.
eco:b0341.
PATRICi32115815. VBIEscCol129921_0349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23219 Genomic DNA. Translation: AAA23627.1.
U73857 Genomic DNA. Translation: AAB18065.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73444.1.
AP009048 Genomic DNA. Translation: BAE76123.1.
PIRiE64761. BVECCX.
RefSeqiNP_414875.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP17583.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263183. 8 interactions.
STRINGi511145.b0341.

Protein family/group databases

TCDBi2.A.1.17.1. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP17583.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73444; AAC73444; b0341.
BAE76123; BAE76123; BAE76123.
GeneIDi946770.
KEGGiecj:JW0332.
eco:b0341.
PATRICi32115815. VBIEscCol129921_0349.

Organism-specific databases

EchoBASEiEB0174.
EcoGeneiEG10177. cynX.

Phylogenomic databases

eggNOGiENOG4105DJ2. Bacteria.
COG2807. LUCA.
HOGENOMiHOG000273879.
InParanoidiP17583.
KOiK03449.
OMAiGYIMGGF.
PhylomeDBiP17583.

Enzyme and pathway databases

BioCyciEcoCyc:CYNX-MONOMER.
ECOL316407:JW0332-MONOMER.

Miscellaneous databases

PROiP17583.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004747. Cyan_transport.
IPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00896. CynX. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCYNX_ECOLI
AccessioniPrimary (citable) accession number: P17583
Secondary accession number(s): P71308, P75695, Q2MC83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 124 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.