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Protein

Cyanate transport protein CynX

Gene

cynX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein is part of an active transport system that transports exogenous cyanate into E.coli cells.

GO - Biological processi

  • cyanate catabolic process Source: EcoCyc
  • transmembrane transport Source: InterPro

Keywordsi

Biological processTransport

Enzyme and pathway databases

BioCyciEcoCyc:CYNX-MONOMER

Protein family/group databases

TCDBi2.A.1.17.1 the major facilitator superfamily (mfs)

Names & Taxonomyi

Protein namesi
Recommended name:
Cyanate transport protein CynX
Gene namesi
Name:cynX
Ordered Locus Names:b0341, JW0332
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10177 cynX

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Transmembranei68 – 88HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei122 – 142HelicalSequence analysisAdd BLAST21
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21
Transmembranei287 – 307HelicalSequence analysisAdd BLAST21
Transmembranei322 – 342HelicalSequence analysisAdd BLAST21
Transmembranei354 – 374HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002057071 – 384Cyanate transport protein CynXAdd BLAST384

Proteomic databases

PaxDbiP17583
PRIDEiP17583

Interactioni

Protein-protein interaction databases

BioGridi4263183, 8 interactors
STRINGi316385.ECDH10B_1354

Structurei

3D structure databases

ProteinModelPortaliP17583
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJ2 Bacteria
COG2807 LUCA
HOGENOMiHOG000273879
InParanoidiP17583
KOiK03449
OMAiGGYTSMV
PhylomeDBiP17583

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR004747 Cyan_transport
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00896 CynX, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

P17583-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLVLVLIGL NMRPLLTSVG PLLPQLRQAS GMSFSVAALL TALPVVTMGG
60 70 80 90 100
LALAGSWLHQ HVSERRSVAI SLLLIAVGAL MRELYPQSAL LLSSALLGGV
110 120 130 140 150
GIGIIQAVMP SVIKRRFQQR TPLVMGLWSA ALMGGGGLGA AITPWLVQHS
160 170 180 190 200
ETWYQTLAWW ALPAVVALFA WWWQSAREVA SSHKTTTTPV RVVFTPRAWT
210 220 230 240 250
LGVYFGLING GYASLIAWLP AFYIEIGASA QYSGSLLALM TLGQAAGALL
260 270 280 290 300
MPAMARHQDR RKLLMLALVL QLVGFCGFIW LPMQLPVLWA MVCGLGLGGA
310 320 330 340 350
FPLCLLLALD HSVQPAIAGK LVAFMQGIGF IIAGLAPWFS GVLRSISGNY
360 370 380
LMDWAFHALC VVGLMIITLR FAPVRFPQLW VKEA
Length:384
Mass (Da):41,361
Last modified:November 1, 1997 - v2
Checksum:i05A579C7988E90A7
GO

Sequence cautioni

The sequence AAB18065 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti27R → A in AAA23627 (PubMed:3049588).Curated1
Sequence conflicti336 – 384APWFS…WVKEA → PRGFLACCVVSAAIT (PubMed:3049588).CuratedAdd BLAST49

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M23219 Genomic DNA Translation: AAA23627.1
U73857 Genomic DNA Translation: AAB18065.1 Different initiation.
U00096 Genomic DNA Translation: AAC73444.1
AP009048 Genomic DNA Translation: BAE76123.1
PIRiE64761 BVECCX
RefSeqiNP_414875.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAC73444; AAC73444; b0341
BAE76123; BAE76123; BAE76123
GeneIDi946770
KEGGiecj:JW0332
eco:b0341
PATRICifig|511145.12.peg.349

Entry informationi

Entry nameiCYNX_ECOLI
AccessioniPrimary (citable) accession number: P17583
Secondary accession number(s): P71308, P75695, Q2MC83
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health