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Protein

60S acidic ribosomal protein P1-alpha 3

Gene

rpp102

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the elongation step of protein synthesis.

Miscellaneous

Yeasts contain 4 individual small ribosomal A proteins (RPA) which can be classified into two couples of similar but not identical sequences. Each couple is distinctly related to one of the two A proteins present in multicellular organisms.
Rpa3 and rpa4 are essential for cell survival, whereas rpa1 and rpa2 are not.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-SPO-1799339 SRP-dependent cotranslational protein targeting to membrane
R-SPO-72689 Formation of a pool of free 40S subunits
R-SPO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-SPO-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-SPO-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P1-alpha 3
Short name:
A3
Gene namesi
Name:rpp102
Synonyms:rpa3
ORF Names:SPBC3B9.13c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC3B9.13c
PomBaseiSPBC3B9.13c rpp102

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001577081 – 11060S acidic ribosomal protein P1-alpha 3Add BLAST110

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP17477
PaxDbiP17477
PRIDEiP17477

PTM databases

iPTMnetiP17477

Interactioni

Subunit structurei

P1 and P2 exist as dimers at the large ribosomal subunit.

Protein-protein interaction databases

BioGridi2768303 interactors.
STRINGi4896.SPBC3B9.13c.1

Structurei

3D structure databases

SMRiP17477
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000229898
InParanoidiP17477
KOiK02942
OMAiQELLCTY
OrthoDBiEOG092C5X8C
PhylomeDBiP17477

Family and domain databases

Gene3Di1.10.10.14101 hit
HAMAPiMF_01478 Ribosomal_L12_arch, 1 hit
InterProiView protein in InterPro
IPR038716 P1/P2_N_sf
IPR027534 Ribosomal_L12

Sequencei

Sequence statusi: Complete.

P17477-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASELATSY SALILADEGI EITSDKLLSL TKAANVDVEP IWATIFAKAL
60 70 80 90 100
EGKDLKELLL NIGSAAAAPA AGGAGAPAAA AGGEAAAEEQ KEEAKEEEES
110
DEDMGFGLFD
Length:110
Mass (Da):11,171
Last modified:August 1, 1990 - v1
Checksum:i1734AC9779F5A891
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33139 Genomic DNA Translation: AAA35336.1
CU329671 Genomic DNA Translation: CAA17793.1
PIRiC34715 R6BYP3
RefSeqiNP_596671.1, NM_001022593.2

Genome annotation databases

EnsemblFungiiSPBC3B9.13c.1; SPBC3B9.13c.1:pep; SPBC3B9.13c
GeneIDi2540299
KEGGispo:SPBC3B9.13c

Similar proteinsi

Entry informationi

Entry nameiRLA3_SCHPO
AccessioniPrimary (citable) accession number: P17477
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: April 25, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome