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Protein

60S acidic ribosomal protein P1-alpha 3

Gene

rpp102

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays an important role in the elongation step of protein synthesis.

Miscellaneous

Yeasts contain 4 individual small ribosomal A proteins (RPA) which can be classified into two couples of similar but not identical sequences. Each couple is distinctly related to one of the two A proteins present in multicellular organisms.
Rpa3 and rpa4 are essential for cell survival, whereas rpa1 and rpa2 are not.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-SPO-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SPO-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SPO-72689. Formation of a pool of free 40S subunits.
R-SPO-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SPO-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SPO-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S acidic ribosomal protein P1-alpha 3
Short name:
A3
Gene namesi
Name:rpp102
Synonyms:rpa3
ORF Names:SPBC3B9.13c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC3B9.13c.
PomBaseiSPBC3B9.13c. rpp102.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001577081 – 11060S acidic ribosomal protein P1-alpha 3Add BLAST110

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP17477.
PRIDEiP17477.

Interactioni

Subunit structurei

P1 and P2 exist as dimers at the large ribosomal subunit.

Protein-protein interaction databases

BioGridi276830. 1 interactor.
MINTiMINT-4687404.
STRINGi4896.SPBC3B9.13c.1.

Structurei

3D structure databases

SMRiP17477.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000229898.
InParanoidiP17477.
KOiK02942.
OMAiQELLCTY.
OrthoDBiEOG092C5X8C.
PhylomeDBiP17477.

Family and domain databases

HAMAPiMF_01478. Ribosomal_L12_arch. 1 hit.
InterProiView protein in InterPro
IPR027534. Ribosomal_L12.

Sequencei

Sequence statusi: Complete.

P17477-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASELATSY SALILADEGI EITSDKLLSL TKAANVDVEP IWATIFAKAL
60 70 80 90 100
EGKDLKELLL NIGSAAAAPA AGGAGAPAAA AGGEAAAEEQ KEEAKEEEES
110
DEDMGFGLFD
Length:110
Mass (Da):11,171
Last modified:August 1, 1990 - v1
Checksum:i1734AC9779F5A891
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33139 Genomic DNA. Translation: AAA35336.1.
CU329671 Genomic DNA. Translation: CAA17793.1.
PIRiC34715. R6BYP3.
RefSeqiNP_596671.1. NM_001022593.2.

Genome annotation databases

EnsemblFungiiSPBC3B9.13c.1; SPBC3B9.13c.1:pep; SPBC3B9.13c.
GeneIDi2540299.
KEGGispo:SPBC3B9.13c.

Similar proteinsi

Entry informationi

Entry nameiRLA3_SCHPO
AccessioniPrimary (citable) accession number: P17477
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: September 27, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families