P17449 (VRP1_SALCH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
28.1 kDa virulence protein

Alternative name(s):
Protein M3 in mba region

Gene names

Name:	spvA
Ordered Locus Names:	SCH_V03

Encoded on

Plasmid pKDSc50 Ref.1 Ref.2
Plasmid pSCV50 Ref.3

Organism

Salmonella choleraesuis (strain SC-B67) [Complete proteome] [HAMAP]

Taxonomic identifier

321314 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella enterica subsp. enterica serovar Choleraesuis

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Not known. This protein is involved in the virulence of salmonellas.
Sequence similarities	Belongs to the SpvA family.

Ontologies

Keywords
Biological process	Virulence
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	pathogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	28.1 kDa virulence protein		PRO_0000221659

Sequences

	Sequence		Length	Mass (Da)
	P17449 [UniParc]. Last modified August 1, 1990. Version 1. Checksum: 1504271488525D6F	FASTA	255	28,184
	10 20 30 40 50 60 MNMNQTTSPA LSQVETAIRV PAGNFAKYNY YSVFDIVRQT RKQFINANMS WPGSRGGKAW 70 80 90 100 110 120 DLAMGQAQYI RCMFRENQLT RRVRGTLQQT PDNGTNLSSS AVGGIQGQAE RRPDLATLMV 130 140 150 160 170 180 VNDAINQQIP TLLPYHFPHD QVELSLLNTD VSLEDIISES SIDWPWFLSN SLTGDNSNYA 190 200 210 220 230 240 MELASRLSPE QQTLPTEPDN STATDLTSFY QTNLGLKTAD YTPFEALNTF ARQLAITVPP 250 GGTVDCGYSA CQPAV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequences of genes encoding 32 kDa and 70 kDa polypeptides in mba region of the virulence plasmid, pKDSc50, of Salmonella choleraesuis." Matsui H. Nucleic Acids Res. 18:2181-2181(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: RF-1.
[2]	"Complete DNA sequence and comparative analysis of the 50-kilobase virulence plasmid of Salmonella enterica serovar Choleraesuis." Haneda T., Okada N., Nakazawa N., Kawakami T., Danbara H. Infect. Immun. 69:2612-2620(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: RF-1.
[3]	"The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen." Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S., Lee Y.-S. Nucleic Acids Res. 33:1690-1698(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SC-B67.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X52035 Genomic DNA. Translation: CAA36277.1. AB040415 Genomic DNA. Translation: BAB20510.1. AY509003 Genomic DNA. Translation: AAS58876.1.
PIR	S09497.
RefSeq	NP_073227.1. NC_002638.1. YP_001598061.1. NC_010119.1. YP_209257.1. NC_006855.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	321314.SCV03.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAS58876; AAS58876; SCH_V03.
GeneID	3283349. 5788067. 875763.
KEGG	sec:SCV03.
PATRIC	32319951. VBISalEnt136302_0005.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	RCLFREN.
ProtClustDB	PRK15212.
Enzyme and pathway databases
BioCyc	SENT321314:GJCS-4835-MONOMER.
Family and domain databases
InterPro	IPR018003. Insecticidal_toxin/plasmid_vir. IPR003518. Plasmid_virulence_protein. [Graphical view]
Pfam	PF03538. VRP1. 3 hits. [Graphical view]
PRINTS	PR01340. SALSPVAPROT.
ProtoNet	Search...

Entry information

Entry name

VRP1_SALCH

Accession

Primary (citable) accession number: P17449
Secondary accession number(s): Q5J4C9, Q7DIJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	August 1, 1990
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program