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Protein

Alpha-amylase/trypsin inhibitor CM3

Gene
N/A
Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Alpha-amylase/trypsin inhibitor. It could be involved in insect defense mechanisms.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Alpha-amylase inhibitor, Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI06.004.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylase/trypsin inhibitor CM3
Alternative name(s):
Chloroform/methanol-soluble protein CM3
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Protein family/group databases

Allergomei1051. Tri a 30.
8191. Tri a 30.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 251 PublicationAdd BLAST25
ChainiPRO_000001434626 – 168Alpha-amylase/trypsin inhibitor CM3Add BLAST143

Post-translational modificationi

Five disulfide bonds are present (Probable), which are essential for the inhibitor activity.

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP17314.

Expressioni

Tissue specificityi

Developing endosperm.

Gene expression databases

ExpressionAtlasiP17314. differential.
GenevisibleiP17314. TA.

Interactioni

Subunit structurei

Subunit of the tetrameric inhibitor.

Structurei

3D structure databases

ProteinModelPortaliP17314.
SMRiP17314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG093617CP.

Family and domain databases

Gene3Di1.10.120.10. 1 hit.
InterProiIPR006106. Allergen/soft/tryp_amyl_inhib.
IPR006105. Allergen/tryp_amyl_inhib_CS.
IPR016140. Bifunc_inhib/LTP/seed_store.
IPR013771. Trypsin/amylase_inhib.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00808. AMLASEINHBTR.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.
PROSITEiPS00426. CEREAL_TRYP_AMYL_INH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17314-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACKSSCSLL LLAAVLLSVL AAASASGSCV PGVAFRTNLL PHCRDYVLQQ
60 70 80 90 100
TCGTFTPGSK LPEWMTSASI YSPGKPYLAK LYCCQELAEI SQQCRCEALR
110 120 130 140 150
YFIALPVPSQ PVDPRSGNVG ESGLIDLPGC PREMQWDFVR LLVAPGQCNL
160
ATIHNVRYCP AVEQPLWI
Length:168
Mass (Da):18,221
Last modified:August 1, 1990 - v1
Checksum:iA950FF272E90D23C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17574 mRNA. Translation: CAA35597.1.
X61032 mRNA. Translation: CAA43367.1.
PIRiS10029.
UniGeneiTa.817.

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.
GrameneiTRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17574 mRNA. Translation: CAA35597.1.
X61032 mRNA. Translation: CAA43367.1.
PIRiS10029.
UniGeneiTa.817.

3D structure databases

ProteinModelPortaliP17314.
SMRiP17314.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei1051. Tri a 30.
8191. Tri a 30.0101.
MEROPSiI06.004.

Proteomic databases

PRIDEiP17314.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.
GrameneiTRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.2; TRIAE_CS42_4BL_TGACv1_321643_AA1063570.

Phylogenomic databases

OrthoDBiEOG093617CP.

Gene expression databases

ExpressionAtlasiP17314. differential.
GenevisibleiP17314. TA.

Family and domain databases

Gene3Di1.10.120.10. 1 hit.
InterProiIPR006106. Allergen/soft/tryp_amyl_inhib.
IPR006105. Allergen/tryp_amyl_inhib_CS.
IPR016140. Bifunc_inhib/LTP/seed_store.
IPR013771. Trypsin/amylase_inhib.
[Graphical view]
PfamiPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSiPR00808. AMLASEINHBTR.
SMARTiSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMiSSF47699. SSF47699. 1 hit.
PROSITEiPS00426. CEREAL_TRYP_AMYL_INH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIAAC3_WHEAT
AccessioniPrimary (citable) accession number: P17314
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: November 30, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

CM proteins would be involved in the cooking quality of pasta.

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.