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Protein

Spermatid nuclear transition protein 1

Gene

TNP1

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Differentiation, Spermatogenesis

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatid nuclear transition protein 1
Short name:
STP-1
Short name:
TP-1
Gene namesi
Name:TNP1
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 15

Subcellular locationi

GO - Cellular componenti

  • male germ cell nucleus Source: GO_Central
  • nucleosome Source: UniProtKB
  • nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleosome core, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001914192 – 55Spermatid nuclear transition protein 1Add BLAST54

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei9PhosphoserineBy similarity1
Modified residuei37PhosphoserineBy similarity1
Modified residuei40PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP17306.
PRIDEiP17306.

PTM databases

iPTMnetiP17306.

Expressioni

Tissue specificityi

Testis.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017139.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410JJTU. Eukaryota.
ENOG4111B50. LUCA.
GeneTreeiENSGT00390000000539.
HOGENOMiHOG000136637.
InParanoidiP17306.
OMAiKRCDDAN.
TreeFamiTF338391.

Family and domain databases

InterProiIPR001319. Nuclear_transition_prot1.
IPR020062. Nuclear_transition_prot1_CS.
[Graphical view]
PANTHERiPTHR17486. PTHR17486. 1 hit.
PfamiPF02079. TP1. 1 hit.
[Graphical view]
ProDomiPD010292. TP1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS00541. TP1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17306-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSRKLKSH GMRRGKNRAP HKGVKRGGSK RKYRKGSLKS RKRCDDANRN

YRSHL
Length:55
Mass (Da):6,424
Last modified:January 23, 2007 - v2
Checksum:iFA740830174A7D35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16170 mRNA. Translation: CAA34292.1.
M80679 Genomic DNA. No translation available.
PIRiS21670. BGPG.
RefSeqiXP_003133695.1. XM_003133647.3.
UniGeneiSsc.59347.

Genome annotation databases

EnsembliENSSSCT00000017617; ENSSSCP00000017139; ENSSSCG00000016179.
GeneIDi100513764.
KEGGissc:100513764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X16170 mRNA. Translation: CAA34292.1.
M80679 Genomic DNA. No translation available.
PIRiS21670. BGPG.
RefSeqiXP_003133695.1. XM_003133647.3.
UniGeneiSsc.59347.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017139.

PTM databases

iPTMnetiP17306.

Proteomic databases

PaxDbiP17306.
PRIDEiP17306.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000017617; ENSSSCP00000017139; ENSSSCG00000016179.
GeneIDi100513764.
KEGGissc:100513764.

Organism-specific databases

CTDi7141.

Phylogenomic databases

eggNOGiENOG410JJTU. Eukaryota.
ENOG4111B50. LUCA.
GeneTreeiENSGT00390000000539.
HOGENOMiHOG000136637.
InParanoidiP17306.
OMAiKRCDDAN.
TreeFamiTF338391.

Family and domain databases

InterProiIPR001319. Nuclear_transition_prot1.
IPR020062. Nuclear_transition_prot1_CS.
[Graphical view]
PANTHERiPTHR17486. PTHR17486. 1 hit.
PfamiPF02079. TP1. 1 hit.
[Graphical view]
ProDomiPD010292. TP1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEiPS00541. TP1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSTP1_PIG
AccessioniPrimary (citable) accession number: P17306
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.