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P17224 (T1RP_ECOLX) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Type I restriction enzyme EcoprrI

EC=3.1.21.3
Gene names
Name:prrD
OrganismEscherichia coli
Taxonomic identifier562 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative 'masking-agent' for the anticodon nuclease. Recognizes the double-stranded sequence 5'-CCAN7RTGC-3'.

Catalytic activity

Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

Sequence similarities

Belongs to the HsdR family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 313313Type I restriction enzyme EcoprrI
PRO_0000077261

Sequences

Sequence LengthMass (Da)Tools
P17224 [UniParc].

Last modified August 1, 1990. Version 1.
Checksum: FB2628D6630ED828

FASTA31337,036
        10         20         30         40         50         60 
MVDCTKPIAE SNNFIILDKY NPDWKITESY QSEGDLEREL IQDLVNQGYE YLPTLNNTKA 

        70         80         90        100        110        120 
MLANVREQLQ NLNNVEFLEA EWRRFVETWM DKPSDGVVEK ARKIHDDYVH DFVFDDGRIQ 

       130        140        150        160        170        180 
NIYLLDRKNI LRNKVQVIKQ FEQAGTHANR YDVTILVNGL PLVQIELKKR GVAIREAFNQ 

       190        200        210        220        230        240 
IHRYSKESFN SENSLFKYLQ LFVISNGTDT RYFANTTKRD KNSFDFTMNW AKSDNTLIKD 

       250        260        270        280        290        300 
LKDFTATFFQ KHTLLNVLVN YSVFDSSQTL LVMRPYQIAA TERILWKIKS SFTSEELVKT 

       310 
GKRWVYLAHY RFW 

« Hide

References

[1]"The optional E. coli prr locus encodes a latent form of phage T4-induced anticodon nuclease."
Levitz R., Chapman D., Amitsur M., Green R., Snyder L., Kaufmann G.
EMBO J. 9:1383-1389(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: CTR5X.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X52284 Genomic DNA. Translation: CAA36528.1.
PIRS09628.

3D structure databases

ProteinModelPortalP17224.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

REBASE2541. EcoprrI.

Proteomic databases

PRIDEP17224.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR007409. Restrct_endonuc_type1_HsdR_N.
[Graphical view]
PfamPF04313. HSDR_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameT1RP_ECOLX
AccessionPrimary (citable) accession number: P17224
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Restriction enzymes and methylases

Classification of restriction enzymes and methylases and list of entries