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P17202

- BADH_SPIOL

UniProt

P17202 - BADH_SPIOL

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Protein

Betaine aldehyde dehydrogenase, chloroplastic

Gene
N/A
Organism
Spinacia oleracea (Spinach)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Betaine aldehyde + NAD+ + H2O = betaine + NADH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei159 – 1591Transition state stabilizerBy similarity
Active sitei257 – 2571Proton acceptorPROSITE-ProRule annotation
Active sitei291 – 2911NucleophilePROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi235 – 2406NADBy similarity

GO - Molecular functioni

  1. betaine-aldehyde dehydrogenase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycine betaine biosynthetic process from choline Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

UniPathwayiUPA00529; UER00386.

Names & Taxonomyi

Protein namesi
Recommended name:
Betaine aldehyde dehydrogenase, chloroplastic (EC:1.2.1.8)
Short name:
BADH
OrganismiSpinacia oleracea (Spinach)
Taxonomic identifieri3562 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeCaryophyllalesAmaranthaceaeChenopodioideaeAnserineaeSpinacia

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 77ChloroplastSequence Analysis
Chaini8 – 497490Betaine aldehyde dehydrogenase, chloroplasticPRO_0000007182Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei8 – 81Blocked amino end (Arg)

Interactioni

Subunit structurei

Homodimer.

Structurei

Secondary structure

1
497
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi10 – 123Combined sources
Beta strandi15 – 173Combined sources
Beta strandi24 – 285Combined sources
Turni30 – 323Combined sources
Beta strandi35 – 406Combined sources
Helixi44 – 5916Combined sources
Turni61 – 633Combined sources
Beta strandi64 – 663Combined sources
Helixi68 – 8417Combined sources
Helixi86 – 9712Combined sources
Helixi101 – 12525Combined sources
Turni126 – 1305Combined sources
Beta strandi140 – 1489Combined sources
Beta strandi150 – 1556Combined sources
Beta strandi158 – 1603Combined sources
Helixi161 – 17515Combined sources
Beta strandi178 – 1825Combined sources
Helixi189 – 20113Combined sources
Beta strandi207 – 2104Combined sources
Helixi215 – 22410Combined sources
Beta strandi230 – 2356Combined sources
Helixi237 – 24812Combined sources
Turni249 – 2513Combined sources
Beta strandi254 – 2574Combined sources
Beta strandi263 – 2664Combined sources
Beta strandi268 – 2703Combined sources
Helixi272 – 28413Combined sources
Helixi285 – 2884Combined sources
Beta strandi296 – 3005Combined sources
Helixi301 – 31616Combined sources
Helixi336 – 35217Combined sources
Beta strandi368 – 3703Combined sources
Beta strandi375 – 3795Combined sources
Helixi385 – 3884Combined sources
Beta strandi393 – 40311Combined sources
Helixi404 – 4118Combined sources
Beta strandi418 – 4236Combined sources
Helixi427 – 43610Combined sources
Beta strandi439 – 4468Combined sources
Helixi460 – 4623Combined sources
Turni469 – 4713Combined sources
Helixi472 – 4765Combined sources
Beta strandi477 – 4859Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4A0MX-ray2.30A/B/C/D1-496[»]
ProteinModelPortaliP17202.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P17202-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAFPIPARQL FIDGEWREPI KKNRIPVINP STEEIIGDIP AATAEDVEVA
60 70 80 90 100
VVAARRAFRR NNWSATSGAH RATYLRAIAA KITEKKDHFV KLETIDSGKP
110 120 130 140 150
FDEAVLDIDD VASCFEYFAG QAEALDGKQK APVTLPMERF KSHVLRQPLG
160 170 180 190 200
VVGLISPWNY PLLMATWKIA PALAAGCTAV LKPSELASVT CLEFGEVCNE
210 220 230 240 250
VGLPPGVLNI LTGLGPDAGA PLVSHPDVDK IAFTGSSATG SKVMASAAQL
260 270 280 290 300
VKPVTLELGG KSPIVVFEDV DIDKVVEWTI FGCFWTNGQI CSATSRLLVH
310 320 330 340 350
ESIAAEFVDK LVKWTKNIKI SDPFEEGCRL GPVISKGQYD KIMKFISTAK
360 370 380 390 400
SEGATILYGG SRPEHLKKGY YIEPTIVTDI STSMQIWKEE VFGPVLCVKT
410 420 430 440 450
FSSEDEAIAL ANDTEYGLAA AVFSNDLERC ERITKALEVG AVWVNCSQPC
460 470 480 490
FVQAPWGGIK RSGFGRELGE WGIQNYLNIK QVTQDISDEP WGWYKSP
Length:497
Mass (Da):54,270
Last modified:November 1, 1990 - v1
Checksum:i55088240E635B22F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti424 – 4241S → F in AAB41696. 1 PublicationCurated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31480 mRNA. Translation: AAA34025.1.
U69142 Genomic DNA. Translation: AAB41696.1.
PIRiA35994.
T51173.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31480 mRNA. Translation: AAA34025.1 .
U69142 Genomic DNA. Translation: AAB41696.1 .
PIRi A35994.
T51173.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4A0M X-ray 2.30 A/B/C/D 1-496 [» ]
ProteinModelPortali P17202.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00529 ; UER00386 .

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of a plant betaine-aldehyde dehydrogenase, an enzyme implicated in adaptation to salinity and drought."
    Weretilnyk E.A., Hanson A.D.
    Proc. Natl. Acad. Sci. U.S.A. 87:2745-2749(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Strain: cv. Savoy hybrid 612.
  2. Shu W., Ai W., Chen S.
    Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiBADH_SPIOL
AccessioniPrimary (citable) accession number: P17202
Secondary accession number(s): P93555
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1990
Last sequence update: November 1, 1990
Last modified: November 26, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3