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Protein

40S ribosomal protein S19

Gene

Rps19

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Required for pre-rRNA processing and maturation of 40S ribosomal subunits.By similarity

GO - Molecular functioni

  • fibroblast growth factor binding Source: RGD
  • protein complex binding Source: RGD
  • protein homodimerization activity Source: RGD
  • protein kinase binding Source: RGD
  • RNA binding Source: RGD
  • structural constituent of ribosome Source: HGNC
  • translation initiation factor binding Source: UniProtKB

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S19
Gene namesi
Name:Rps19
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi68440. Rps19.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001538141 – 14540S ribosomal protein S19Add BLAST145

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei23N6-acetyllysineBy similarity1
Modified residuei67Omega-N-methylarginineBy similarity1
Modified residuei111N6-acetyllysineBy similarity1
Modified residuei115N6-acetyllysineBy similarity1
Modified residuei143N6-succinyllysineBy similarity1

Keywords - PTMi

Acetylation, Methylation

Proteomic databases

PaxDbiP17074.
PRIDEiP17074.

PTM databases

iPTMnetiP17074.
PhosphoSitePlusiP17074.

Expressioni

Gene expression databases

BgeeiENSRNOG00000037897.
GenevisibleiP17074. RN.

Interactioni

Subunit structurei

Interacts with RPS19BP1.By similarity

GO - Molecular functioni

  • fibroblast growth factor binding Source: RGD
  • protein complex binding Source: RGD
  • protein homodimerization activity Source: RGD
  • protein kinase binding Source: RGD
  • translation initiation factor binding Source: UniProtKB

Protein-protein interaction databases

BioGridi247957. 1 interactor.
IntActiP17074. 3 interactors.
MINTiMINT-4580819.
STRINGi10116.ENSRNOP00000066808.

Structurei

3D structure databases

ProteinModelPortaliP17074.
SMRiP17074.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3411. Eukaryota.
COG2238. LUCA.
GeneTreeiENSGT00390000013102.
HOGENOMiHOG000230649.
HOVERGENiHBG000240.
InParanoidiP17074.
KOiK02966.
OrthoDBiEOG091G0QM7.
PhylomeDBiP17074.
TreeFamiTF315008.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR001266. Ribosomal_S19e.
IPR018277. Ribosomal_S19e_CS.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PANTHERiPTHR11710. PTHR11710. 1 hit.
PfamiView protein in Pfam
PF01090. Ribosomal_S19e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003854. Ribosomal_S19e. 1 hit.
SMARTiView protein in SMART
SM01413. Ribosomal_S19e. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS00628. RIBOSOMAL_S19E. 1 hit.

Sequencei

Sequence statusi: Complete.

P17074-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGVTVKDVN QQEFVRALAA FLKKSGKLKV PEWVDTVKLA KHKELAPYDE
60 70 80 90 100
NWFYTRAAST ARHLYLRGGA GVGSMTKIYG GRQRNGVRPS HFSRGSKSVA
110 120 130 140
RRVLQALEGL KMVEKDQDGG RKLTPQGQRD LDRIAGQVAA ANKKH
Length:145
Mass (Da):16,085
Last modified:January 23, 2007 - v3
Checksum:i180032B887FA6E41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51707 mRNA. Translation: CAA36003.1.
BC087641 mRNA. Translation: AAH87641.1.
PIRiA43770. R3RT19.
RefSeqiNP_001032423.1. NM_001037346.2.
XP_006228473.1. XM_006228411.1.
XP_017444775.1. XM_017589286.1.
XP_017444777.1. XM_017589288.1.
XP_017445502.1. XM_017590013.1.
UniGeneiRn.115882.
Rn.127775.

Genome annotation databases

EnsembliENSRNOT00000027246; ENSRNOP00000027246; ENSRNOG00000037897.
GeneIDi108348115.
29287.
KEGGirno:108348115.
rno:29287.
UCSCiRGD:68440. rat.

Similar proteinsi

Entry informationi

Entry nameiRS19_RAT
AccessioniPrimary (citable) accession number: P17074
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 136 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families