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Protein

Phytoene synthase

Gene

crtB

Organism
Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).By similarity

Cofactori

Protein has several cofactor binding sites:
  • ATPBy similarityNote: ATP is required for the transferase activity but it does not seem to be hydrolyzed during the reaction.By similarity
  • Mn2+By similarity, Mg2+By similarity

Pathwayi: phytoene biosynthesis

This protein is involved in the pathway phytoene biosynthesis, which is part of Carotenoid biosynthesis.
View all proteins of this organism that are known to be involved in the pathway phytoene biosynthesis and in Carotenoid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processCarotenoid biosynthesis
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-14934
RCAP272942:G1GUE-684-MONOMER
UniPathwayiUPA00799

Names & Taxonomyi

Protein namesi
Recommended name:
Phytoene synthase (EC:2.5.1.-)
Short name:
PSase
Gene namesi
Name:crtB
Ordered Locus Names:RCAP_rcc00680
OrganismiRhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Taxonomic identifieri272942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002361 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000674331 – 339Phytoene synthaseAdd BLAST339

Proteomic databases

PRIDEiP17056

Interactioni

Protein-protein interaction databases

STRINGi272942.RCAP_rcc00680

Structurei

3D structure databases

ProteinModelPortaliP17056
SMRiP17056
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phytoene/squalene synthase family.Curated

Phylogenomic databases

eggNOGiENOG4105FE1 Bacteria
COG1562 LUCA
HOGENOMiHOG000220848
KOiK02291
OMAiCRVADDA
OrthoDBiPOG091H0EAX

Family and domain databases

CDDicd00683 Trans_IPPS_HH, 1 hit
Gene3Di1.10.600.10, 1 hit
InterProiView protein in InterPro
IPR008949 Isoprenoid_synthase_dom_sf
IPR002060 Squ/phyt_synthse
IPR019845 Squalene/phytoene_synthase_CS
IPR033904 Trans_IPPS_HH
PfamiView protein in Pfam
PF00494 SQS_PSY, 1 hit
SUPFAMiSSF48576 SSF48576, 1 hit
PROSITEiView protein in PROSITE
PS01044 SQUALEN_PHYTOEN_SYN_1, 1 hit
PS01045 SQUALEN_PHYTOEN_SYN_2, 1 hit

Sequencei

Sequence statusi: Complete.

P17056-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAEADMEVC RELIRTGSYS FHAASRVLPA RVRDPALALY AFCRVADDEV
60 70 80 90 100
DEVGAPRDKA AAVLKLGDRL EDIYAGRPRN APSDRAFAAV VEEFEMPREL
110 120 130 140 150
PEALLEGFAW DAEGRWYHTL SDVQAYSARV AAAVGAMMCV LMRVRNPDAL
160 170 180 190 200
ARACDLGLAM QMSNIARDVG EDARAGRLFL PTDWMVEEGI DPQAFLADPQ
210 220 230 240 250
PTKGIRRVTE RLLNRADRLY WRAATGVRLL PFDCRPGIMA AGKIYAAIGA
260 270 280 290 300
EVAKAKYDNI TRRAHTTKGR KLWLVANSAM SATATSMLPL SPRVHAKPEP
310 320 330
EVAHLVDAAA HRNLHPERSE VLISALMALK ARDRGLAMD
Length:339
Mass (Da):37,302
Last modified:August 1, 1990 - v1
Checksum:i6D7052994934BF4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52291 Genomic DNA Translation: CAA36534.1
Z11165 Genomic DNA Translation: CAA77541.1
CP001312 Genomic DNA Translation: ADE84445.1
PIRiS04403
RefSeqiWP_013066424.1, NC_014034.1

Genome annotation databases

EnsemblBacteriaiADE84445; ADE84445; RCAP_rcc00680
GeneIDi31489626
KEGGircp:RCAP_rcc00680

Similar proteinsi

Entry informationi

Entry nameiCRTB_RHOCB
AccessioniPrimary (citable) accession number: P17056
Secondary accession number(s): D5AP73
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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