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P17056 (CRTB_RHOCB) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phytoene synthase

Short name=PSase
EC=2.5.1.-
Gene names
Name:crtB
Ordered Locus Names:RCAP_rcc00680
OrganismRhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) [Complete proteome] [HAMAP]
Taxonomic identifier272942 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene By similarity.

Cofactor

ATP. ATP is required for the transferase activity but it does not seem to be hydrolyzed during the reaction By similarity.

Manganese or magnesium By similarity.

Pathway

Carotenoid biosynthesis; phytoene biosynthesis.

Sequence similarities

Belongs to the phytoene/squalene synthase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 339339Phytoene synthase
PRO_0000067433

Sequences

Sequence LengthMass (Da)Tools
P17056 [UniParc].

Last modified August 1, 1990. Version 1.
Checksum: 6D7052994934BF4F

FASTA33937,302
        10         20         30         40         50         60 
MIAEADMEVC RELIRTGSYS FHAASRVLPA RVRDPALALY AFCRVADDEV DEVGAPRDKA 

        70         80         90        100        110        120 
AAVLKLGDRL EDIYAGRPRN APSDRAFAAV VEEFEMPREL PEALLEGFAW DAEGRWYHTL 

       130        140        150        160        170        180 
SDVQAYSARV AAAVGAMMCV LMRVRNPDAL ARACDLGLAM QMSNIARDVG EDARAGRLFL 

       190        200        210        220        230        240 
PTDWMVEEGI DPQAFLADPQ PTKGIRRVTE RLLNRADRLY WRAATGVRLL PFDCRPGIMA 

       250        260        270        280        290        300 
AGKIYAAIGA EVAKAKYDNI TRRAHTTKGR KLWLVANSAM SATATSMLPL SPRVHAKPEP 

       310        320        330 
EVAHLVDAAA HRNLHPERSE VLISALMALK ARDRGLAMD 

« Hide

References

« Hide 'large scale' references
[1]"Nucleotide sequence, organization, and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus."
Armstrong G.A., Alberti M., Leach F., Hearst J.E.
Mol. Gen. Genet. 216:254-268(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
[2]"Complete genome sequence of the photosynthetic purple nonsulfur bacterium Rhodobacter capsulatus SB 1003."
Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V., Haselkorn R.
J. Bacteriol. 192:3545-3546(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-309 / NBRC 16581 / SB1003.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X52291 Genomic DNA. Translation: CAA36534.1.
Z11165 Genomic DNA. Translation: CAA77541.1.
CP001312 Genomic DNA. Translation: ADE84445.1.
PIRS04403.
RefSeqYP_003576852.1. NC_014034.1.

3D structure databases

ProteinModelPortalP17056.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADE84445; ADE84445; RCAP_rcc00680.
GeneID9003509.
KEGGrcp:RCAP_rcc00680.
PATRIC35501428. VBIRhoCap134200_0691.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000220848.
KOK02291.
OMAMMTLVMG.
ProtClustDBCLSK924105.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14934.
RCAP272942:GJIY-693-MONOMER.
UniPathwayUPA00799.

Family and domain databases

Gene3D1.10.600.10. 1 hit.
InterProIPR002060. Squ/phyt_synthse.
IPR019845. Squalene/phytoene_synthase_CS.
IPR008949. Terpenoid_synth.
[Graphical view]
PfamPF00494. SQS_PSY. 1 hit.
[Graphical view]
SUPFAMSSF48576. SSF48576. 1 hit.
PROSITEPS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit.
PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCRTB_RHOCB
AccessionPrimary (citable) accession number: P17056
Secondary accession number(s): D5AP73
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 16, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways