P17056 (CRTB_RHOCB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phytoene synthase
EC=2.5.1.32

Gene names

Name:	crtB
Ordered Locus Names:	RCAP_rcc00680

Organism

Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) [Complete proteome] [HAMAP]

Taxonomic identifier

272942 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter › Rhodobacter capsulatus

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the reaction from prephytoene diphosphate to phytoene.
Catalytic activity	2 geranylgeranyl diphosphate = 15-cis-phytoene + 2 diphosphate.
Pathway	Carotenoid biosynthesis; phytoene biosynthesis; all-trans-phytoene from geranylgeranyl diphosphate: step 1/1.
Sequence similarities	Belongs to the phytoene/squalene synthase family.

Ontologies

Keywords
Biological process	Carotenoid biosynthesis Chlorophyll biosynthesis
Molecular function	Transferase
Technical term	Complete proteome Multifunctional enzyme
Gene Ontology (GO)
Biological_process	carotenoid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	geranylgeranyl-diphosphate geranylgeranyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 339	339	Phytoene synthase		PRO_0000067433

Sequences

	Sequence		Length	Mass (Da)
	P17056 [UniParc]. Last modified August 1, 1990. Version 1. Checksum: 6D7052994934BF4F	FASTA	339	37,302
	10 20 30 40 50 60 MIAEADMEVC RELIRTGSYS FHAASRVLPA RVRDPALALY AFCRVADDEV DEVGAPRDKA 70 80 90 100 110 120 AAVLKLGDRL EDIYAGRPRN APSDRAFAAV VEEFEMPREL PEALLEGFAW DAEGRWYHTL 130 140 150 160 170 180 SDVQAYSARV AAAVGAMMCV LMRVRNPDAL ARACDLGLAM QMSNIARDVG EDARAGRLFL 190 200 210 220 230 240 PTDWMVEEGI DPQAFLADPQ PTKGIRRVTE RLLNRADRLY WRAATGVRLL PFDCRPGIMA 250 260 270 280 290 300 AGKIYAAIGA EVAKAKYDNI TRRAHTTKGR KLWLVANSAM SATATSMLPL SPRVHAKPEP 310 320 330 EVAHLVDAAA HRNLHPERSE VLISALMALK ARDRGLAMD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence, organization, and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus." Armstrong G.A., Alberti M., Leach F., Hearst J.E. Mol. Gen. Genet. 216:254-268(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
[2]	"Complete genome sequence of the photosynthetic purple nonsulfur bacterium Rhodobacter capsulatus SB 1003." Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V., Haselkorn R. J. Bacteriol. 192:3545-3546(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-309 / NBRC 16581 / SB1003.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X52291 Genomic DNA. Translation: CAA36534.1. Z11165 Genomic DNA. Translation: CAA77541.1. CP001312 Genomic DNA. Translation: ADE84445.1.
PIR	S04403.
RefSeq	YP_003576852.1. NC_014034.1.
3D structure databases
ProteinModelPortal	P17056.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADE84445; ADE84445; RCAP_rcc00680.
GeneID	9003509.
KEGG	rcp:RCAP_rcc00680.
PATRIC	35501428. VBIRhoCap134200_0691.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000220848.
KO	K02291.
OMA	MMTLVMG.
ProtClustDB	CLSK924105.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14934. RCAP272942:GJIY-693-MONOMER.
UniPathway	UPA00799; UER00773.
Family and domain databases
Gene3D	1.10.600.10. 1 hit.
InterPro	IPR002060. Squ/phyt_synthse. IPR019845. Squalene/phytoene_synthase_CS. IPR008949. Terpenoid_synth. [Graphical view]
Pfam	PF00494. SQS_PSY. 1 hit. [Graphical view]
SUPFAM	SSF48576. Terpenoid_synth. 1 hit.
PROSITE	PS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit. PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CRTB_RHOCB

Accession

Primary (citable) accession number: P17056
Secondary accession number(s): D5AP73

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	August 1, 1990
Last modified:	May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program