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P17056

- CRTB_RHOCB

UniProt

P17056 - CRTB_RHOCB

Protein

Phytoene synthase

Gene

crtB

Organism
Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Aug 1990)
      Previous versions | rss
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    Functioni

    Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene By similarity.By similarity

    Cofactori

    ATP. ATP is required for the transferase activity but it does not seem to be hydrolyzed during the reaction By similarity.By similarity
    Manganese or magnesium.By similarity

    Pathwayi

    GO - Molecular functioni

    1. geranylgeranyl-diphosphate geranylgeranyltransferase activity Source: UniProtKB
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. carotenoid biosynthetic process Source: UniProtKB

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Carotenoid biosynthesis

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-14934.
    RCAP272942:GJIY-693-MONOMER.
    UniPathwayiUPA00799.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phytoene synthase (EC:2.5.1.-)
    Short name:
    PSase
    Gene namesi
    Name:crtB
    Ordered Locus Names:RCAP_rcc00680
    OrganismiRhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
    Taxonomic identifieri272942 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
    ProteomesiUP000002361: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 339339Phytoene synthasePRO_0000067433Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP17056.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the phytoene/squalene synthase family.Curated

    Phylogenomic databases

    HOGENOMiHOG000220848.
    KOiK02291.
    OMAiMMTLVMG.

    Family and domain databases

    Gene3Di1.10.600.10. 1 hit.
    InterProiIPR002060. Squ/phyt_synthse.
    IPR019845. Squalene/phytoene_synthase_CS.
    IPR008949. Terpenoid_synth.
    [Graphical view]
    PfamiPF00494. SQS_PSY. 1 hit.
    [Graphical view]
    SUPFAMiSSF48576. SSF48576. 1 hit.
    PROSITEiPS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit.
    PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P17056-1 [UniParc]FASTAAdd to Basket

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    MIAEADMEVC RELIRTGSYS FHAASRVLPA RVRDPALALY AFCRVADDEV    50
    DEVGAPRDKA AAVLKLGDRL EDIYAGRPRN APSDRAFAAV VEEFEMPREL 100
    PEALLEGFAW DAEGRWYHTL SDVQAYSARV AAAVGAMMCV LMRVRNPDAL 150
    ARACDLGLAM QMSNIARDVG EDARAGRLFL PTDWMVEEGI DPQAFLADPQ 200
    PTKGIRRVTE RLLNRADRLY WRAATGVRLL PFDCRPGIMA AGKIYAAIGA 250
    EVAKAKYDNI TRRAHTTKGR KLWLVANSAM SATATSMLPL SPRVHAKPEP 300
    EVAHLVDAAA HRNLHPERSE VLISALMALK ARDRGLAMD 339
    Length:339
    Mass (Da):37,302
    Last modified:August 1, 1990 - v1
    Checksum:i6D7052994934BF4F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52291 Genomic DNA. Translation: CAA36534.1.
    Z11165 Genomic DNA. Translation: CAA77541.1.
    CP001312 Genomic DNA. Translation: ADE84445.1.
    PIRiS04403.
    RefSeqiWP_013066424.1. NC_014034.1.
    YP_003576852.1. NC_014034.1.

    Genome annotation databases

    EnsemblBacteriaiADE84445; ADE84445; RCAP_rcc00680.
    GeneIDi9003509.
    KEGGircp:RCAP_rcc00680.
    PATRICi35501428. VBIRhoCap134200_0691.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52291 Genomic DNA. Translation: CAA36534.1 .
    Z11165 Genomic DNA. Translation: CAA77541.1 .
    CP001312 Genomic DNA. Translation: ADE84445.1 .
    PIRi S04403.
    RefSeqi WP_013066424.1. NC_014034.1.
    YP_003576852.1. NC_014034.1.

    3D structure databases

    ProteinModelPortali P17056.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADE84445 ; ADE84445 ; RCAP_rcc00680 .
    GeneIDi 9003509.
    KEGGi rcp:RCAP_rcc00680.
    PATRICi 35501428. VBIRhoCap134200_0691.

    Phylogenomic databases

    HOGENOMi HOG000220848.
    KOi K02291.
    OMAi MMTLVMG.

    Enzyme and pathway databases

    UniPathwayi UPA00799 .
    BioCyci MetaCyc:MONOMER-14934.
    RCAP272942:GJIY-693-MONOMER.

    Family and domain databases

    Gene3Di 1.10.600.10. 1 hit.
    InterProi IPR002060. Squ/phyt_synthse.
    IPR019845. Squalene/phytoene_synthase_CS.
    IPR008949. Terpenoid_synth.
    [Graphical view ]
    Pfami PF00494. SQS_PSY. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48576. SSF48576. 1 hit.
    PROSITEi PS01044. SQUALEN_PHYTOEN_SYN_1. 1 hit.
    PS01045. SQUALEN_PHYTOEN_SYN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence, organization, and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus."
      Armstrong G.A., Alberti M., Leach F., Hearst J.E.
      Mol. Gen. Genet. 216:254-268(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC BAA-309 / NBRC 16581 / SB1003.
    2. "Complete genome sequence of the photosynthetic purple nonsulfur bacterium Rhodobacter capsulatus SB 1003."
      Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V., Haselkorn R.
      J. Bacteriol. 192:3545-3546(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-309 / NBRC 16581 / SB1003.

    Entry informationi

    Entry nameiCRTB_RHOCB
    AccessioniPrimary (citable) accession number: P17056
    Secondary accession number(s): D5AP73
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1990
    Last sequence update: August 1, 1990
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3