ZSCAN20

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	710 – 732	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	738 – 760	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	766 – 788	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	794 – 816	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	875 – 897	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	903 – 925	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	931 – 953	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	959 – 981	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	987 – 1009	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	1015 – 1037	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
metal ion binding Source: UniProtKB-KW
transcription factor activity, sequence-specific DNA binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

transcription, DNA-templated Source: UniProtKB-KW

Complete GO annotation...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger and SCAN domain-containing protein 20 Alternative name(s): Zinc finger protein 31 Zinc finger protein 360 Zinc finger protein KOX29
Gene namesⁱ	Name:ZSCAN20 Synonyms:KOX29, ZNF31, ZNF360
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13093. ZSCAN20.

HGNCⁱ

HGNC:13093. ZSCAN20.

Subcellular locationⁱ

Nucleus
PROSITE-ProRule annotation
Manual assertion according to rulesⁱ
- PROSITE-ProRule:PRU00187

GO - Cellular componentⁱ

nucleus Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	7579.
Open Targets More...OpenTargetsⁱ	ENSG00000121903.
PharmGKBⁱ	PA37668.

Polymorphism and mutation databases

BioMutaⁱ	ZSCAN20.
DMDMⁱ	229485383.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047360	1 – 1043	Zinc finger and SCAN domain-containing protein 20Add BLAST		1043

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P17040.
PaxDbⁱ	P17040.
PeptideAtlas More...PeptideAtlasⁱ	P17040.
PRIDEⁱ	P17040.

PTM databases

iPTMnetⁱ	P17040.
PhosphoSitePlusⁱ	P17040.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000121903.
CleanExⁱ	HS_ZSCAN20.
Genevisibleⁱ	P17040. HS.

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA017933.

HPAⁱ

HPA017933.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	113408. 58 interactors.
IntActⁱ	P17040. 1 interactor.
Molecular INTeraction database More...MINTⁱ	MINT-1456758.
STRINGⁱ	9606.ENSP00000324450.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P17040.
SMRⁱ	P17040.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	51 – 133	SCAN boxPROSITE-ProRule annotationAdd BLAST		83

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	710 – 732	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	738 – 760	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	766 – 788	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	794 – 816	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	875 – 897	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	903 – 925	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	931 – 953	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	959 – 981	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	987 – 1009	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	1015 – 1037	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063287.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P17040.
KEGG Orthology (KO) More...KOⁱ	K09230.
OMAⁱ	IDHQGLY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P17040.
TreeFamⁱ	TF337082.

Family and domain databases

InterProⁱ	View protein in InterPro IPR008916. Retrov_capsid_C. IPR001005. SANT/Myb. IPR003309. SCAN_dom. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02023. SCAN. 1 hit.
SMARTⁱ	View protein in SMART SM00717. SANT. 2 hits. SM00431. SCAN. 1 hit. SM00355. ZnF_C2H2. 10 hits.
SUPFAMⁱ	SSF47353. SSF47353. 1 hit. SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50804. SCAN_BOX. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 10 hits. PS50157. ZINC_FINGER_C2H2_2. 10 hits.

Sequences (4)ⁱ

Sequence statusⁱ: Complete.

This entry describes 4 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: P17040-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SAVLTPRVPT LPKMGSVGDW EVTAESQEAL GPGKHAEKEL CKDPPGDDCG 
       260        270        280        290        300
NSVCLGVPVS KPSNTSEKEQ GPEFWGLSLI NSGKRSTADY SLDNEPAQAL 
       310        320        330        340        350
TWRDSRAWEE QYQWDVEDMK VSGVHWGYEE TKTFLAILSE SPFSEKLRTC 
       360        370        380        390        400
HQNRQVYRAI AEQLRARGFL RTLEQCRYRV KNLLRNYRKA KSSHPPGTCP 
       410        420        430        440        450
FYEELEALVR ARTAIRATDG PGEAVALPRL GYSDAEMDEQ EEGGWDPEEM 
       460        470        480        490        500
AEDCNGAGLV NVESTQGPRI AGAPALFQSR IAGVHWGYEE TKAFLAILSE 
       510        520        530        540        550
SPFSEKLRTC HQNSQVYRAI AERLCALGFL RTLEQCRYRF KNLLRSYRKA 
       560        570        580        590        600
KSSHPPGTCP FYEELDSLMR ARAAVRAMGT VREAAGLPRC GQSSAETDAQ 
       610        620        630        640        650
EAWGEVANED AVKPSTLCPK APDMGFEMRH EDEDQISEQD IFEGLPGALS 
       660        670        680        690        700
KCPTEAVCQP LDWGEDSENE NEDEGQWGNP SQEQWQESSS EEDLEKLIDH 
       710        720        730        740        750
QGLYLAEKPY KCDTCMKSFS RSSHFIAHQR IHTGEKPYKC LECGKNFSDR 
       760        770        780        790        800
SNLNTHQRIH TGEKPYKCLE CGKSFSDHSN LITHQRIHTG EKPYKCGECW 
       810        820        830        840        850
KSFNQSSNLL KHQRIHLGGN PDQCSEPGGN FAQSPSFSAH WRNSTEETAP 
       860        870        880        890        900
EQPQSISKDL NSPGPHSTNS GEKLYECSEC GRSFSKSSAL ISHQRIHTGE 
       910        920        930        940        950
KPYECAECGK SFSKSSTLAN HQRTHTGEKP YKCVDCGKCF SERSKLITHQ 
       960        970        980        990       1000
RVHTGEKPYK CLECGKFFRD RSNLITHQRI HTGEKPYKCR ECGKCFNQSS 
      1010       1020       1030       1040 
SLIIHQRIHT GEKPYKCTEC GKDFNNSSHF SAHRRTHAGG KAS

Length:1,043

Mass (Da):117,541

Last modified:March 24, 2009 - v3

Checksum:ⁱ1598FB5F243773FE

GO

Isoform 2 (identifier: P17040-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
25-90: Missing.

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        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLELLVL EQFLTILPRE VQTWVQARHP 
        60         70         80         90        100
ESGEEAVALV EDWHRETRTA GQSGLELHTE ETRPLKTGEE AQSFQLQPVD 
       110        120        130        140        150
PWPEGQSQKK GVKNTCPDLP NHLNAEVAPQ PLKESAVLTP RVPTLPKMGS 
       160        170        180        190        200
VGDWEVTAES QEALGPGKHA EKELCKDPPG DDCGNSVCLG VPVSKPSNTS 
       210        220        230        240        250
EKEQGPEFWG LSLINSGKRS TADYSLDNEP AQALTWRDSR AWEEQYQWDV 
       260        270        280        290        300
EDMKVSGVHW GYEETKTFLA ILSESPFSEK LRTCHQNRQV YRAIAEQLRA 
       310        320        330        340        350
RGFLRTLEQC RYRVKNLLRN YRKAKSSHPP GTCPFYEELE ALVRARTAIR 
       360        370        380        390        400
ATDGPGEAVA LPRLGYSDAE MDEQEEGGWD PEEMAEDCNG AGLVNVESTQ 
       410        420        430        440        450
GPRIAGAPAL FQSRIAGVHW GYEETKAFLA ILSESPFSEK LRTCHQNSQV 
       460        470        480        490        500
YRAIAERLCA LGFLRTLEQC RYRFKNLLRS YRKAKSSHPP GTCPFYEELD 
       510        520        530        540        550
SLMRARAAVR AMGTVREAAG LPRCGQSSAE TDAQEAWGEV ANEDAVKPST 
       560        570        580        590        600
LCPKAPDMGF EMRHEDEDQI SEQDIFEGLP GALSKCPTEA VCQPLDWGED 
       610        620        630        640        650
SENENEDEGQ WGNPSQEQWQ ESSSEEDLEK LIDHQGLYLA EKPYKCDTCM 
       660        670        680        690        700
KSFSRSSHFI AHQRIHTGEK PYKCLECGKN FSDRSNLNTH QRIHTGEKPY 
       710        720        730        740        750
KCLECGKSFS DHSNLITHQR IHTGEKPYKC GECWKSFNQS SNLLKHQRIH 
       760        770        780        790        800
LGGNPDQCSE PGGNFAQSPS FSAHWRNSTE ETAPEQPQSI SKDLNSPGPH 
       810        820        830        840        850
STNSGEKLYE CSECGRSFSK SSALISHQRI HTGEKPYECA ECGKSFSKSS 
       860        870        880        890        900
TLANHQRTHT GEKPYKCVDC GKCFSERSKL ITHQRVHTGE KPYKCLECGK 
       910        920        930        940        950
FFRDRSNLIT HQRIHTGEKP YKCRECGKCF NQSSSLIIHQ RIHTGEKPYK 
       960        970 
CTECGKDFNN SSHFSAHRRT HAGGKAS

Show »

Length:977

Mass (Da):109,706

Checksum:ⁱ5E283FEE045D4525

GO

Isoform 3 (identifier: P17040-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
482-482: Missing.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SAVLTPRVPT LPKMGSVGDW EVTAESQEAL GPGKHAEKEL CKDPPGDDCG 
       260        270        280        290        300
NSVCLGVPVS KPSNTSEKEQ GPEFWGLSLI NSGKRSTADY SLDNEPAQAL 
       310        320        330        340        350
TWRDSRAWEE QYQWDVEDMK VSGVHWGYEE TKTFLAILSE SPFSEKLRTC 
       360        370        380        390        400
HQNRQVYRAI AEQLRARGFL RTLEQCRYRV KNLLRNYRKA KSSHPPGTCP 
       410        420        430        440        450
FYEELEALVR ARTAIRATDG PGEAVALPRL GYSDAEMDEQ EEGGWDPEEM 
       460        470        480        490        500
AEDCNGAGLV NVESTQGPRI AGAPALFQSR IGVHWGYEET KAFLAILSES 
       510        520        530        540        550
PFSEKLRTCH QNSQVYRAIA ERLCALGFLR TLEQCRYRFK NLLRSYRKAK 
       560        570        580        590        600
SSHPPGTCPF YEELDSLMRA RAAVRAMGTV REAAGLPRCG QSSAETDAQE 
       610        620        630        640        650
AWGEVANEDA VKPSTLCPKA PDMGFEMRHE DEDQISEQDI FEGLPGALSK 
       660        670        680        690        700
CPTEAVCQPL DWGEDSENEN EDEGQWGNPS QEQWQESSSE EDLEKLIDHQ 
       710        720        730        740        750
GLYLAEKPYK CDTCMKSFSR SSHFIAHQRI HTGEKPYKCL ECGKNFSDRS 
       760        770        780        790        800
NLNTHQRIHT GEKPYKCLEC GKSFSDHSNL ITHQRIHTGE KPYKCGECWK 
       810        820        830        840        850
SFNQSSNLLK HQRIHLGGNP DQCSEPGGNF AQSPSFSAHW RNSTEETAPE 
       860        870        880        890        900
QPQSISKDLN SPGPHSTNSG EKLYECSECG RSFSKSSALI SHQRIHTGEK 
       910        920        930        940        950
PYECAECGKS FSKSSTLANH QRTHTGEKPY KCVDCGKCFS ERSKLITHQR 
       960        970        980        990       1000
VHTGEKPYKC LECGKFFRDR SNLITHQRIH TGEKPYKCRE CGKCFNQSSS 
      1010       1020       1030       1040 
LIIHQRIHTG EKPYKCTECG KDFNNSSHFS AHRRTHAGGK AS

Note: No experimental confirmation available.

Show »

Length:1,042

Mass (Da):117,470

Checksum:ⁱ68BCA6E9110E3EB0

GO

Isoform 4 (identifier: P17040-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
     202-255: Missing.
     482-487: AGVHWG → GKNMGV
     488-1043: Missing.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SGVPVSKPSN TSEKEQGPEF WGLSLINSGK RSTADYSLDN EPAQALTWRD 
       260        270        280        290        300
SRAWEEQYQW DVEDMKVSGV HWGYEETKTF LAILSESPFS EKLRTCHQNR 
       310        320        330        340        350
QVYRAIAEQL RARGFLRTLE QCRYRVKNLL RNYRKAKSSH PPGTCPFYEE 
       360        370        380        390        400
LEALVRARTA IRATDGPGEA VALPRLGYSD AEMDEQEEGG WDPEEMAEDC 
       410        420        430 
NGAGLVNVES TQGPRIAGAP ALFQSRIGKN MGV

Note: No experimental confirmation available.

Show »

Length:433

Mass (Da):49,035

Checksum:ⁱ63C40A82025DB27B

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	100	L → P in BAF82884 (PubMed:14702039).Curated	1
Sequence conflictⁱ	126	V → M in BAF82884 (PubMed:14702039).Curated	1
Sequence conflictⁱ	740	C → R in BAD18552 (PubMed:14702039).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_054799	248	D → N. Corresponds to variant dbSNP:rs34446695Ensembl.		1
Natural variantⁱVAR_054800	432	Y → D3 PublicationsCorresponds to variant dbSNP:rs4403594Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_036735	25 – 90	Missing in isoform 2. 1 PublicationAdd BLAST	66
Alternative sequenceⁱVSP_036736	202 – 255	Missing in isoform 4. 1 PublicationAdd BLAST	54
Alternative sequenceⁱVSP_036737	482 – 487	AGVHWG → GKNMGV in isoform 4. 1 Publication	6
Alternative sequenceⁱVSP_036738	482	Missing in isoform 3. 1 Publication	1
Alternative sequenceⁱVSP_036739	488 – 1043	Missing in isoform 4. 1 PublicationAdd BLAST	556

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK131405 mRNA. Translation: BAD18552.1. AK290195 mRNA. Translation: BAF82884.1. AL138837, AC115285 Genomic DNA. Translation: CAI19593.1. AL138837, AC115285 Genomic DNA. Translation: CAI19594.1. AL138837, AC115285 Genomic DNA. Translation: CAM12881.1. CH471059 Genomic DNA. Translation: EAX07454.1. BC008827 mRNA. Translation: AAH08827.1. BC011404 mRNA. Translation: AAH11404.1. X52360 mRNA. Translation: CAA36586.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41300.1. [P17040-1]
PIRⁱ	I37969.
NCBI Reference Sequences More...RefSeqⁱ	NP_660281.2. NM_145238.3. XP_005271228.1. XM_005271171.3. [P17040-3] XP_006710937.1. XM_006710874.3. [P17040-1] XP_016857726.1. XM_017002237.1. [P17040-1] XP_016857727.1. XM_017002238.1. [P17040-3]
UniGeneⁱ	Hs.442705.

Genome annotation databases

Ensemblⁱ	ENST00000361328; ENSP00000355053; ENSG00000121903. [P17040-1] ENST00000373413; ENSP00000362512; ENSG00000121903. [P17040-4]
GeneIDⁱ	7579.
KEGGⁱ	hsa:7579.
UCSC genome browser More...UCSCⁱ	uc001bxj.5. human. [P17040-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
P17040	UPI0007DC7B10 F7GWX2 H9FEV1 H9FGD6 H9FF03 G3QSE2 H2R053 A0A0D9S7V0 A0A096MUB0 G1QST2 +29	Homo sapiens (Human) Macaca mulatta (Rhesus macaque) Gorilla gorilla gorilla (Western lowland gorilla) Pan troglodytes (Chimpanzee) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Papio anubis (Olive baboon) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Pan paniscus (Pygmy chimpanzee) (Bonobo) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Colobus angolensis palliatus (Peters' Angolan colobus) And more	1,043	UniRef90_P17040	Cluster: Zinc finger and SCAN domain-containing protein 20	40

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
P17040	UPI0007DC7B10 UPI00053345FE UPI0005F451CE UPI0004F089B6 G1QST2 UPI0007DBB167 UPI0005F4BD48 A0A096MUB0 A0A0D9S7V0 UPI0005F3E282 +127	Homo sapiens (Human) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Macaca nemestrina (Pig-tailed macaque) Pan paniscus (Pygmy chimpanzee) (Bonobo) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Pan troglodytes (Chimpanzee) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Papio anubis (Olive baboon) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) And more	1,043	UniRef50_P17040	Cluster: Zinc finger and SCAN domain-containing protein 20	138
P17040-4	F7GQB7 F7HXR2	Macaca mulatta (Rhesus macaque) Callithrix jacchus (White-tufted-ear marmoset)	433	UniRef50_P17040-4	Cluster: Isoform 4 of Zinc finger and SCAN domain-containing protein 20	3

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK131405 mRNA. Translation: BAD18552.1. AK290195 mRNA. Translation: BAF82884.1. AL138837, AC115285 Genomic DNA. Translation: CAI19593.1. AL138837, AC115285 Genomic DNA. Translation: CAI19594.1. AL138837, AC115285 Genomic DNA. Translation: CAM12881.1. CH471059 Genomic DNA. Translation: EAX07454.1. BC008827 mRNA. Translation: AAH08827.1. BC011404 mRNA. Translation: AAH11404.1. X52360 mRNA. Translation: CAA36586.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41300.1. [P17040-1]
PIRⁱ	I37969.
NCBI Reference Sequences More...RefSeqⁱ	NP_660281.2. NM_145238.3. XP_005271228.1. XM_005271171.3. [P17040-3] XP_006710937.1. XM_006710874.3. [P17040-1] XP_016857726.1. XM_017002237.1. [P17040-1] XP_016857727.1. XM_017002238.1. [P17040-3]
UniGeneⁱ	Hs.442705.

3D structure databases

ProteinModelPortalⁱ	P17040.
SMRⁱ	P17040.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	113408. 58 interactors.
IntActⁱ	P17040. 1 interactor.
Molecular INTeraction database More...MINTⁱ	MINT-1456758.
STRINGⁱ	9606.ENSP00000324450.

PTM databases

iPTMnetⁱ	P17040.
PhosphoSitePlusⁱ	P17040.

Polymorphism and mutation databases

BioMutaⁱ	ZSCAN20.
DMDMⁱ	229485383.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P17040.
PaxDbⁱ	P17040.
PeptideAtlas More...PeptideAtlasⁱ	P17040.
PRIDEⁱ	P17040.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000361328; ENSP00000355053; ENSG00000121903. [P17040-1] ENST00000373413; ENSP00000362512; ENSG00000121903. [P17040-4]
GeneIDⁱ	7579.
KEGGⁱ	hsa:7579.
UCSC genome browser More...UCSCⁱ	uc001bxj.5. human. [P17040-1]

Organism-specific databases

CTDⁱ	7579.
DisGeNET More...DisGeNETⁱ	7579.
GeneCardsⁱ	ZSCAN20.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13093. ZSCAN20.
Human Protein Atlas More...HPAⁱ	HPA017933.
MIMⁱ	611315. gene.
neXtProtⁱ	NX_P17040.
Open Targets More...OpenTargetsⁱ	ENSG00000121903.
PharmGKBⁱ	PA37668.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063287.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P17040.
KEGG Orthology (KO) More...KOⁱ	K09230.
OMAⁱ	IDHQGLY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P17040.
TreeFamⁱ	TF337082.

Miscellaneous databases

GenomeRNAiⁱ	7579.
Protein Ontology More...PROⁱ	PR:P17040.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000121903.
CleanExⁱ	HS_ZSCAN20.
Genevisibleⁱ	P17040. HS.

Family and domain databases

InterProⁱ	View protein in InterPro IPR008916. Retrov_capsid_C. IPR001005. SANT/Myb. IPR003309. SCAN_dom. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02023. SCAN. 1 hit.
SMARTⁱ	View protein in SMART SM00717. SANT. 2 hits. SM00431. SCAN. 1 hit. SM00355. ZnF_C2H2. 10 hits.
SUPFAMⁱ	SSF47353. SSF47353. 1 hit. SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50804. SCAN_BOX. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 10 hits. PS50157. ZINC_FINGER_C2H2_2. 10 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZSC20_HUMAN
Accessionⁱ	P17040Primary (citable) accession number: P17040 Secondary accession number(s): A8K2D0 Q96H84
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
	Last sequence update:	March 24, 2009
	Last modified:	August 30, 2017
	This is version 169 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

UniProtKB

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UniProtKB - P17040 (ZSC20_HUMAN)

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Zinc finger and SCAN domain-containing protein 20

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequences (4)ⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ