ZSCAN20

Functionⁱ

May be involved in transcriptional regulation.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	710 – 732	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	738 – 760	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	766 – 788	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	794 – 816	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	875 – 897	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	903 – 925	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	931 – 953	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	959 – 981	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	987 – 1009	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	1015 – 1037	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
metal ion binding Source: UniProtKB-KW
RNA polymerase II transcription factor activity, sequence-specific DNA binding
Source: NTNU_SB
Inferred from sequence modelⁱ
- 19274049

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger and SCAN domain-containing protein 20 Alternative name(s): Zinc finger protein 31 Zinc finger protein 360 Zinc finger protein KOX29
Gene namesⁱ	Name:ZSCAN20 Synonyms:KOX29, ZNF31, ZNF360
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000121903.14.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13093. ZSCAN20.
MIMⁱ	611315. gene.
neXtProtⁱ	NX_P17040.

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	7579.
Open Targets More...OpenTargetsⁱ	ENSG00000121903.
PharmGKBⁱ	PA37668.

Polymorphism and mutation databases

BioMutaⁱ	ZSCAN20.
DMDMⁱ	229485383.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000047360	1 – 1043	Zinc finger and SCAN domain-containing protein 20Add BLAST		1043

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P17040.
PaxDbⁱ	P17040.
PeptideAtlas More...PeptideAtlasⁱ	P17040.
PRIDEⁱ	P17040.

PTM databases

iPTMnetⁱ	P17040.
PhosphoSitePlusⁱ	P17040.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000121903.
CleanExⁱ	HS_ZSCAN20.
Genevisibleⁱ	P17040. HS.

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA017933.

HPAⁱ

HPA017933.

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
ZKSCAN4	A0A0S2Z6X0	3	EBI-16440054,EBI-16431094

With

Entry

#Exp.

IntAct

Notes

ZKSCAN4

A0A0S2Z6X0

3

EBI-16440054,EBI-16431094

Protein-protein interaction databases

BioGridⁱ	113408. 58 interactors.
IntActⁱ	P17040. 2 interactors.
STRINGⁱ	9606.ENSP00000324450.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P17040.
SMRⁱ	P17040.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	51 – 133	SCAN boxPROSITE-ProRule annotationAdd BLAST		83

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	710 – 732	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	738 – 760	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	766 – 788	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	794 – 816	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	875 – 897	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	903 – 925	C2H2-type 6PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	931 – 953	C2H2-type 7PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	959 – 981	C2H2-type 8PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	987 – 1009	C2H2-type 9PROSITE-ProRule annotationAdd BLAST	23
Zinc fingerⁱ	1015 – 1037	C2H2-type 10PROSITE-ProRule annotationAdd BLAST	23

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063287.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P17040.
KEGG Orthology (KO) More...KOⁱ	K09230.
OMAⁱ	IDHQGLY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P17040.
TreeFamⁱ	TF337082.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07936. SCAN. 1 hit.
Gene3Dⁱ	1.10.4020.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001005. SANT/Myb. IPR003309. SCAN_dom. IPR038269. SCAN_sf. IPR036236. Znf_C2H2_sf. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02023. SCAN. 1 hit.
SMARTⁱ	View protein in SMART SM00717. SANT. 2 hits. SM00431. SCAN. 1 hit. SM00355. ZnF_C2H2. 10 hits.
SUPFAMⁱ	SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50804. SCAN_BOX. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 10 hits. PS50157. ZINC_FINGER_C2H2_2. 10 hits.

Sequences (4)ⁱ

Sequence statusⁱ: Complete.

This entry describes 4 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: P17040-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SAVLTPRVPT LPKMGSVGDW EVTAESQEAL GPGKHAEKEL CKDPPGDDCG 
       260        270        280        290        300
NSVCLGVPVS KPSNTSEKEQ GPEFWGLSLI NSGKRSTADY SLDNEPAQAL 
       310        320        330        340        350
TWRDSRAWEE QYQWDVEDMK VSGVHWGYEE TKTFLAILSE SPFSEKLRTC 
       360        370        380        390        400
HQNRQVYRAI AEQLRARGFL RTLEQCRYRV KNLLRNYRKA KSSHPPGTCP 
       410        420        430        440        450
FYEELEALVR ARTAIRATDG PGEAVALPRL GYSDAEMDEQ EEGGWDPEEM 
       460        470        480        490        500
AEDCNGAGLV NVESTQGPRI AGAPALFQSR IAGVHWGYEE TKAFLAILSE 
       510        520        530        540        550
SPFSEKLRTC HQNSQVYRAI AERLCALGFL RTLEQCRYRF KNLLRSYRKA 
       560        570        580        590        600
KSSHPPGTCP FYEELDSLMR ARAAVRAMGT VREAAGLPRC GQSSAETDAQ 
       610        620        630        640        650
EAWGEVANED AVKPSTLCPK APDMGFEMRH EDEDQISEQD IFEGLPGALS 
       660        670        680        690        700
KCPTEAVCQP LDWGEDSENE NEDEGQWGNP SQEQWQESSS EEDLEKLIDH 
       710        720        730        740        750
QGLYLAEKPY KCDTCMKSFS RSSHFIAHQR IHTGEKPYKC LECGKNFSDR 
       760        770        780        790        800
SNLNTHQRIH TGEKPYKCLE CGKSFSDHSN LITHQRIHTG EKPYKCGECW 
       810        820        830        840        850
KSFNQSSNLL KHQRIHLGGN PDQCSEPGGN FAQSPSFSAH WRNSTEETAP 
       860        870        880        890        900
EQPQSISKDL NSPGPHSTNS GEKLYECSEC GRSFSKSSAL ISHQRIHTGE 
       910        920        930        940        950
KPYECAECGK SFSKSSTLAN HQRTHTGEKP YKCVDCGKCF SERSKLITHQ 
       960        970        980        990       1000
RVHTGEKPYK CLECGKFFRD RSNLITHQRI HTGEKPYKCR ECGKCFNQSS 
      1010       1020       1030       1040 
SLIIHQRIHT GEKPYKCTEC GKDFNNSSHF SAHRRTHAGG KAS

Length:1,043

Mass (Da):117,541

Last modified:March 24, 2009 - v3

Checksum:ⁱ1598FB5F243773FE

GO

Isoform 2 (identifier: P17040-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
25-90: Missing.

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        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLELLVL EQFLTILPRE VQTWVQARHP 
        60         70         80         90        100
ESGEEAVALV EDWHRETRTA GQSGLELHTE ETRPLKTGEE AQSFQLQPVD 
       110        120        130        140        150
PWPEGQSQKK GVKNTCPDLP NHLNAEVAPQ PLKESAVLTP RVPTLPKMGS 
       160        170        180        190        200
VGDWEVTAES QEALGPGKHA EKELCKDPPG DDCGNSVCLG VPVSKPSNTS 
       210        220        230        240        250
EKEQGPEFWG LSLINSGKRS TADYSLDNEP AQALTWRDSR AWEEQYQWDV 
       260        270        280        290        300
EDMKVSGVHW GYEETKTFLA ILSESPFSEK LRTCHQNRQV YRAIAEQLRA 
       310        320        330        340        350
RGFLRTLEQC RYRVKNLLRN YRKAKSSHPP GTCPFYEELE ALVRARTAIR 
       360        370        380        390        400
ATDGPGEAVA LPRLGYSDAE MDEQEEGGWD PEEMAEDCNG AGLVNVESTQ 
       410        420        430        440        450
GPRIAGAPAL FQSRIAGVHW GYEETKAFLA ILSESPFSEK LRTCHQNSQV 
       460        470        480        490        500
YRAIAERLCA LGFLRTLEQC RYRFKNLLRS YRKAKSSHPP GTCPFYEELD 
       510        520        530        540        550
SLMRARAAVR AMGTVREAAG LPRCGQSSAE TDAQEAWGEV ANEDAVKPST 
       560        570        580        590        600
LCPKAPDMGF EMRHEDEDQI SEQDIFEGLP GALSKCPTEA VCQPLDWGED 
       610        620        630        640        650
SENENEDEGQ WGNPSQEQWQ ESSSEEDLEK LIDHQGLYLA EKPYKCDTCM 
       660        670        680        690        700
KSFSRSSHFI AHQRIHTGEK PYKCLECGKN FSDRSNLNTH QRIHTGEKPY 
       710        720        730        740        750
KCLECGKSFS DHSNLITHQR IHTGEKPYKC GECWKSFNQS SNLLKHQRIH 
       760        770        780        790        800
LGGNPDQCSE PGGNFAQSPS FSAHWRNSTE ETAPEQPQSI SKDLNSPGPH 
       810        820        830        840        850
STNSGEKLYE CSECGRSFSK SSALISHQRI HTGEKPYECA ECGKSFSKSS 
       860        870        880        890        900
TLANHQRTHT GEKPYKCVDC GKCFSERSKL ITHQRVHTGE KPYKCLECGK 
       910        920        930        940        950
FFRDRSNLIT HQRIHTGEKP YKCRECGKCF NQSSSLIIHQ RIHTGEKPYK 
       960        970 
CTECGKDFNN SSHFSAHRRT HAGGKAS

Show »

Length:977

Mass (Da):109,706

Checksum:ⁱ5E283FEE045D4525

GO

Isoform 3 (identifier: P17040-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
482-482: Missing.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SAVLTPRVPT LPKMGSVGDW EVTAESQEAL GPGKHAEKEL CKDPPGDDCG 
       260        270        280        290        300
NSVCLGVPVS KPSNTSEKEQ GPEFWGLSLI NSGKRSTADY SLDNEPAQAL 
       310        320        330        340        350
TWRDSRAWEE QYQWDVEDMK VSGVHWGYEE TKTFLAILSE SPFSEKLRTC 
       360        370        380        390        400
HQNRQVYRAI AEQLRARGFL RTLEQCRYRV KNLLRNYRKA KSSHPPGTCP 
       410        420        430        440        450
FYEELEALVR ARTAIRATDG PGEAVALPRL GYSDAEMDEQ EEGGWDPEEM 
       460        470        480        490        500
AEDCNGAGLV NVESTQGPRI AGAPALFQSR IGVHWGYEET KAFLAILSES 
       510        520        530        540        550
PFSEKLRTCH QNSQVYRAIA ERLCALGFLR TLEQCRYRFK NLLRSYRKAK 
       560        570        580        590        600
SSHPPGTCPF YEELDSLMRA RAAVRAMGTV REAAGLPRCG QSSAETDAQE 
       610        620        630        640        650
AWGEVANEDA VKPSTLCPKA PDMGFEMRHE DEDQISEQDI FEGLPGALSK 
       660        670        680        690        700
CPTEAVCQPL DWGEDSENEN EDEGQWGNPS QEQWQESSSE EDLEKLIDHQ 
       710        720        730        740        750
GLYLAEKPYK CDTCMKSFSR SSHFIAHQRI HTGEKPYKCL ECGKNFSDRS 
       760        770        780        790        800
NLNTHQRIHT GEKPYKCLEC GKSFSDHSNL ITHQRIHTGE KPYKCGECWK 
       810        820        830        840        850
SFNQSSNLLK HQRIHLGGNP DQCSEPGGNF AQSPSFSAHW RNSTEETAPE 
       860        870        880        890        900
QPQSISKDLN SPGPHSTNSG EKLYECSECG RSFSKSSALI SHQRIHTGEK 
       910        920        930        940        950
PYECAECGKS FSKSSTLANH QRTHTGEKPY KCVDCGKCFS ERSKLITHQR 
       960        970        980        990       1000
VHTGEKPYKC LECGKFFRDR SNLITHQRIH TGEKPYKCRE CGKCFNQSSS 
      1010       1020       1030       1040 
LIIHQRIHTG EKPYKCTECG KDFNNSSHFS AHRRTHAGGK AS

Note: No experimental confirmation available.

Show »

Length:1,042

Mass (Da):117,470

Checksum:ⁱ68BCA6E9110E3EB0

GO

Isoform 4 (identifier: P17040-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
     202-255: Missing.
     482-487: AGVHWG → GKNMGV
     488-1043: Missing.

« Hide

        10         20         30         40         50
MAMALELQAQ ASPQPEPEEL LIVKLEEDSW GSESKLWEKD RGSVSGPEAS 
        60         70         80         90        100
RQRFRQFQYR DAAGPHEAFS QLWALCCRWL RPEIRLKEQI LELLVLEQFL 
       110        120        130        140        150
TILPREVQTW VQARHPESGE EAVALVEDWH RETRTAGQSG LELHTEETRP 
       160        170        180        190        200
LKTGEEAQSF QLQPVDPWPE GQSQKKGVKN TCPDLPNHLN AEVAPQPLKE 
       210        220        230        240        250
SGVPVSKPSN TSEKEQGPEF WGLSLINSGK RSTADYSLDN EPAQALTWRD 
       260        270        280        290        300
SRAWEEQYQW DVEDMKVSGV HWGYEETKTF LAILSESPFS EKLRTCHQNR 
       310        320        330        340        350
QVYRAIAEQL RARGFLRTLE QCRYRVKNLL RNYRKAKSSH PPGTCPFYEE 
       360        370        380        390        400
LEALVRARTA IRATDGPGEA VALPRLGYSD AEMDEQEEGG WDPEEMAEDC 
       410        420        430 
NGAGLVNVES TQGPRIAGAP ALFQSRIGKN MGV

Note: No experimental confirmation available.

Show »

Length:433

Mass (Da):49,035

Checksum:ⁱ63C40A82025DB27B

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	100	L → P in BAF82884 (PubMed:14702039).Curated	1
Sequence conflictⁱ	126	V → M in BAF82884 (PubMed:14702039).Curated	1
Sequence conflictⁱ	740	C → R in BAD18552 (PubMed:14702039).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_054799	248	D → N. Corresponds to variant dbSNP:rs34446695Ensembl.		1
Natural variantⁱVAR_054800	432	Y → D3 PublicationsCorresponds to variant dbSNP:rs4403594Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_036735	25 – 90	Missing in isoform 2. 1 PublicationAdd BLAST	66
Alternative sequenceⁱVSP_036736	202 – 255	Missing in isoform 4. 1 PublicationAdd BLAST	54
Alternative sequenceⁱVSP_036737	482 – 487	AGVHWG → GKNMGV in isoform 4. 1 Publication	6
Alternative sequenceⁱVSP_036738	482	Missing in isoform 3. 1 Publication	1
Alternative sequenceⁱVSP_036739	488 – 1043	Missing in isoform 4. 1 PublicationAdd BLAST	556

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK131405 mRNA. Translation: BAD18552.1. AK290195 mRNA. Translation: BAF82884.1. AL138837, AC115285 Genomic DNA. Translation: CAI19593.1. AL138837, AC115285 Genomic DNA. Translation: CAI19594.1. AL138837, AC115285 Genomic DNA. Translation: CAM12881.1. CH471059 Genomic DNA. Translation: EAX07454.1. BC008827 mRNA. Translation: AAH08827.1. BC011404 mRNA. Translation: AAH11404.1. X52360 mRNA. Translation: CAA36586.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41300.1. [P17040-1]
PIRⁱ	I37969.
NCBI Reference Sequences More...RefSeqⁱ	NP_660281.2. NM_145238.3. XP_005271228.1. XM_005271171.3. [P17040-3] XP_006710937.1. XM_006710874.3. [P17040-1] XP_016857726.1. XM_017002237.1. [P17040-1] XP_016857727.1. XM_017002238.1. [P17040-3]
UniGeneⁱ	Hs.442705.

Genome annotation databases

Ensemblⁱ	ENST00000361328; ENSP00000355053; ENSG00000121903. [P17040-1] ENST00000373413; ENSP00000362512; ENSG00000121903. [P17040-4]
GeneIDⁱ	7579.
KEGGⁱ	hsa:7579.
UCSC genome browser More...UCSCⁱ	uc001bxj.5. human. [P17040-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P17040	UPI0007DC7B10 F7GWX2 A0A2K5TSB1 H9FGD6 H9FEV1 H9FF03 G3QSE2 A0A2J8Y6Z4 UPI0004F46CFD H2R053 +34	Homo sapiens (Human) Macaca mulatta (Rhesus macaque) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Macaca nemestrina (Pig-tailed macaque) And more	1,043	UniRef90_P17040	Cluster: Zinc finger and SCAN domain-containing protein 20	45
P17040-4	F7GQB7 F7HXR2 A0A2I2ZNS7 A0A2J8Y705 A0A2I3T654 A0A2K5NNS4 A0A2K6Q578 A0A2K6S2X0 A0A2K5PU55 A0A2K5HS17 +2	Macaca mulatta (Rhesus macaque) Callithrix jacchus (White-tufted-ear marmoset) Gorilla gorilla gorilla (Western lowland gorilla) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Saimiri boliviensis boliviensis (Bolivian squirrel monkey) Cebus capucinus imitator Colobus angolensis palliatus (Peters' Angolan colobus) And more	433	UniRef90_P17040-4	Cluster: Isoform 4 of Zinc finger and SCAN domain-containing protein 20	13

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P17040	UPI0007DC7B10 A0A2K6AWB6 UPI0004F089B6 G1QST2 H2R053 A0A2J8Y6Z4 UPI0004F46CFD A0A2K5YDU9 UPI000C2B19FD A0A2J8JC83 +123	Homo sapiens (Human) Macaca nemestrina (Pig-tailed macaque) Pan paniscus (Pygmy chimpanzee) (Bonobo) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Pan troglodytes (Chimpanzee) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Mandrillus leucophaeus (Drill) (Papio leucophaeus) Piliocolobus tephrosceles (Ugandan red Colobus) Papio anubis (Olive baboon) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) And more	1,043	UniRef50_P17040	Cluster: Zinc finger and SCAN domain-containing protein 20	134
P17040-4	A0A2K6Q578 A0A2J8Y705 A0A2I3T654 A0A2K6S2X0 A0A2I3GK47 A0A2I2ZNS7 F7GQB7 A0A2K5HS17 A0A2K5NNS4 A0A2K5PU55 +3	Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee) Saimiri boliviensis boliviensis (Bolivian squirrel monkey) Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) Gorilla gorilla gorilla (Western lowland gorilla) Macaca mulatta (Rhesus macaque) Colobus angolensis palliatus (Peters' Angolan colobus) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) Cebus capucinus imitator And more	433	UniRef50_P17040-4	Cluster: Isoform 4 of Zinc finger and SCAN domain-containing protein 20	14

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK131405 mRNA. Translation: BAD18552.1. AK290195 mRNA. Translation: BAF82884.1. AL138837, AC115285 Genomic DNA. Translation: CAI19593.1. AL138837, AC115285 Genomic DNA. Translation: CAI19594.1. AL138837, AC115285 Genomic DNA. Translation: CAM12881.1. CH471059 Genomic DNA. Translation: EAX07454.1. BC008827 mRNA. Translation: AAH08827.1. BC011404 mRNA. Translation: AAH11404.1. X52360 mRNA. Translation: CAA36586.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41300.1. [P17040-1]
PIRⁱ	I37969.
NCBI Reference Sequences More...RefSeqⁱ	NP_660281.2. NM_145238.3. XP_005271228.1. XM_005271171.3. [P17040-3] XP_006710937.1. XM_006710874.3. [P17040-1] XP_016857726.1. XM_017002237.1. [P17040-1] XP_016857727.1. XM_017002238.1. [P17040-3]
UniGeneⁱ	Hs.442705.

3D structure databases

ProteinModelPortalⁱ	P17040.
SMRⁱ	P17040.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	113408. 58 interactors.
IntActⁱ	P17040. 2 interactors.
STRINGⁱ	9606.ENSP00000324450.

PTM databases

iPTMnetⁱ	P17040.
PhosphoSitePlusⁱ	P17040.

Polymorphism and mutation databases

BioMutaⁱ	ZSCAN20.
DMDMⁱ	229485383.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P17040.
PaxDbⁱ	P17040.
PeptideAtlas More...PeptideAtlasⁱ	P17040.
PRIDEⁱ	P17040.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000361328; ENSP00000355053; ENSG00000121903. [P17040-1] ENST00000373413; ENSP00000362512; ENSG00000121903. [P17040-4]
GeneIDⁱ	7579.
KEGGⁱ	hsa:7579.
UCSC genome browser More...UCSCⁱ	uc001bxj.5. human. [P17040-1]

Organism-specific databases

CTDⁱ	7579.
DisGeNET More...DisGeNETⁱ	7579.
EuPathDBⁱ	HostDB:ENSG00000121903.14.
GeneCardsⁱ	ZSCAN20.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:13093. ZSCAN20.
Human Protein Atlas More...HPAⁱ	HPA017933.
MIMⁱ	611315. gene.
neXtProtⁱ	NX_P17040.
Open Targets More...OpenTargetsⁱ	ENSG00000121903.
PharmGKBⁱ	PA37668.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721. Eukaryota. COG5048. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063287.
HOVERGENⁱ	HBG018163.
InParanoidⁱ	P17040.
KEGG Orthology (KO) More...KOⁱ	K09230.
OMAⁱ	IDHQGLY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G02KC.
PhylomeDBⁱ	P17040.
TreeFamⁱ	TF337082.

Miscellaneous databases

GenomeRNAiⁱ	7579.
Protein Ontology More...PROⁱ	PR:P17040.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000121903.
CleanExⁱ	HS_ZSCAN20.
Genevisibleⁱ	P17040. HS.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd07936. SCAN. 1 hit.
Gene3Dⁱ	1.10.4020.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001005. SANT/Myb. IPR003309. SCAN_dom. IPR038269. SCAN_sf. IPR036236. Znf_C2H2_sf. IPR013087. Znf_C2H2_type.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02023. SCAN. 1 hit.
SMARTⁱ	View protein in SMART SM00717. SANT. 2 hits. SM00431. SCAN. 1 hit. SM00355. ZnF_C2H2. 10 hits.
SUPFAMⁱ	SSF57667. SSF57667. 6 hits.
PROSITEⁱ	View protein in PROSITE PS50804. SCAN_BOX. 1 hit. PS00028. ZINC_FINGER_C2H2_1. 10 hits. PS50157. ZINC_FINGER_C2H2_2. 10 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZSC20_HUMAN
Accessionⁱ	P17040Primary (citable) accession number: P17040 Secondary accession number(s): A8K2D0 Q96H84
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
	Last sequence update:	March 24, 2009
	Last modified:	March 28, 2018
	This is version 176 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

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UniProtKB - P17040 (ZSC20_HUMAN)

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Zinc finger and SCAN domain-containing protein 20

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

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Zinc finger

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