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Protein

Protein RhsA

Gene

rhsA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Rhs elements have a nonessential function. They may play an important role in the natural ecology of the cell.

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG10846-MONOMER.
ECOL316407:JW3566-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RhsA
Gene namesi
Name:rhsA
Ordered Locus Names:b3593, JW3566
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10846. rhsA.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000222251 – 1377Protein RhsAAdd BLAST1377

Proteomic databases

PaxDbiP16916.
PRIDEiP16916.

Interactioni

Protein-protein interaction databases

BioGridi4262562. 134 interactors.
DIPiDIP-10699N.
IntActiP16916. 27 interactors.
MINTiMINT-1242055.
STRINGi511145.b3593.

Structurei

3D structure databases

ProteinModelPortaliP16916.
SMRiP16916.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati330 – 3521Add BLAST23
Repeati353 – 3742Add BLAST22
Repeati375 – 4173Add BLAST43
Repeati418 – 4384Add BLAST21
Repeati439 – 4605Add BLAST22
Repeati461 – 4816Add BLAST21
Repeati482 – 5027Add BLAST21
Repeati503 – 5258Add BLAST23
Repeati526 – 5469Add BLAST21
Repeati547 – 56710Add BLAST21
Repeati568 – 58811Add BLAST21
Repeati589 – 60912Add BLAST21
Repeati610 – 62913Add BLAST20
Repeati630 – 65014Add BLAST21
Repeati651 – 67115Add BLAST21
Repeati672 – 69116Add BLAST20
Repeati692 – 71117Add BLAST20
Repeati712 – 73418Add BLAST23
Repeati735 – 75819Add BLAST24
Repeati808 – 82820Add BLAST21
Repeati829 – 85021Add BLAST22
Repeati851 – 87122Add BLAST21
Repeati872 – 89423Add BLAST23
Repeati895 – 93024Add BLAST36
Repeati931 – 95925Add BLAST29
Repeati960 – 98426Add BLAST25
Repeati985 – 101927Add BLAST35
Repeati1162 – 118628Add BLAST25

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni330 – 118628 X approximate tandem repeatsAdd BLAST857

Domaini

Each rhs appears to consist of a highly conserved 141 kDa amino fragment followed by a highly divergent C-terminus.

Sequence similaritiesi

Belongs to the RHS family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CNA. Bacteria.
COG3209. LUCA.
HOGENOMiHOG000225201.
InParanoidiP16916.
OMAiERYYYSW.
PhylomeDBiP16916.

Family and domain databases

InterProiIPR028947. Ntox34.
IPR001826. RHS.
IPR022385. Rhs_assc_core.
IPR031325. RHS_repeat.
IPR006530. YD.
[Graphical view]
PfamiPF15606. Ntox34. 1 hit.
PF03527. RHS. 1 hit.
PF05593. RHS_repeat. 7 hits.
[Graphical view]
PRINTSiPR00394. RHSPROTEIN.
TIGRFAMsiTIGR03696. Rhs_assc_core. 1 hit.
TIGR01643. YD_repeat_2x. 5 hits.

Sequencei

Sequence statusi: Complete.

P16916-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKPAARQG DMTQYGGSIV QGSAGVRIGA PTGVACSVCP GGVTSGHPVN
60 70 80 90 100
PLLGAKVLPG ETDIALPGPL PFILSRTYSS YRTKTPAPVG SLGPGWKMPA
110 120 130 140 150
DIRLQLRDNT LILSDNGGRS LYFEHLFPGE DGYSRSESLW LVRGGVAKLD
160 170 180 190 200
EGHRLAALWQ ALPEELRLSP HRYLATNSPQ GPWWLLGWCE RVPEADEVLP
210 220 230 240 250
APLPPYRVLT GLVDRFGRTQ TFHREAAGEF SGEITGVTDG AWRHFRLVLT
260 270 280 290 300
TQAQRAEEAR QQAISGGTEP SAFPDTLPGY TEYGRDNGIR LSAVWLTHDP
310 320 330 340 350
EYPENLPAAP LVRYGWTPRG ELAVVYDRSG KQVRSFTYDD KYRGRMVAHR
360 370 380 390 400
HTGRPEIRYR YDSDGRVTEQ LNPAGLSYTY QYEKDRITIT DSLDRREVLH
410 420 430 440 450
TQGEAGLKRV VKKEHADGSV TQSQFDAVGR LRAQTDAAGR TTEYSPDVVT
460 470 480 490 500
GLITRITTPD GRASAFYYNH HNQLTSATGP DGLELRREYD ELGRLIQETA
510 520 530 540 550
PDGDITRYRY DNPHSDLPCA TEDATGSRKT MTWSRYGQLL SFTDCSGYVT
560 570 580 590 600
RYDHDRFGQM TAVHREEGLS QYRAYDSRGQ LIAVKDTQGH ETRYEYNIAG
610 620 630 640 650
DLTAVIAPDG SRNGTQYDAW GKAVRTTQGG LTRSMEYDAA GRVIRLTSEN
660 670 680 690 700
GSHTTFRYDV LDRLIQETGF DGRTQRYHHD LTGKLIRSED EGLVTHWHYD
710 720 730 740 750
EADRLTHRTV KGETAERWQY DERGWLTDIS HISEGHRVAV HYRYDEKGRL
760 770 780 790 800
TGERQTVHHP QTEALLWQHE TRHAYNAQGL ANRCIPDSLP AVEWLTYGSG
810 820 830 840 850
YLAGMKLGDT PLVEYTRDRL HRETLRSFGR YELTTAYTPA GQLQSQHLNS
860 870 880 890 900
LLSDRDYTWN DNGELIRISS PRQTRSYSYS TTGRLTGVHT TAANLDIRIP
910 920 930 940 950
YATDPAGNRL PDPELHPDST LSMWPDNRIA RDAHYLYRYD RHGRLTEKTD
960 970 980 990 1000
LIPEGVIRTD DERTHRYHYD SQHRLVHYTR TQYEEPLVES RYLYDPLGRR
1010 1020 1030 1040 1050
VAKRVWRRER DLTGWMSLSR KPQVTWYGWD GDRLTTIQND RTRIQTIYQP
1060 1070 1080 1090 1100
GSFTPLIRVE TATGELAKTQ RRSLADALQQ SGGEDGGSVV FPPVLVQMLD
1110 1120 1130 1140 1150
RLESEILADR VSEESRRWLA SCGLTVEQMQ NQMDPVYTPA RKIHLYHCDH
1160 1170 1180 1190 1200
RGLPLALISK EGTTEWCAEY DEWGNLLNEE NPHQLQQLIR LPGQQYDEES
1210 1220 1230 1240 1250
GLYYNRHRYY DPLQGRYITQ DPIGLKGGWN FYQYPLNPVT NTDPLGLEVF
1260 1270 1280 1290 1300
PRPFPLPIPW PKSPAQQQAD DNAAKALTKW WNDTASQRIF DSLILNNPGL
1310 1320 1330 1340 1350
ALDITMIASR GNVADTGITD RVNDIINDRF WSDGKKPDRC DVLQELIDCG
1360 1370
DISAKDAKST QKAWNCRHSR QSNDKKR
Length:1,377
Mass (Da):156,321
Last modified:August 1, 1990 - v1
Checksum:i21ACA989E74200FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19044 Genomic DNA. Translation: AAC95065.1.
U00039 Genomic DNA. Translation: AAB18570.1.
U00096 Genomic DNA. Translation: AAC76617.1.
AP009048 Genomic DNA. Translation: BAE77700.1.
PIRiC65159.
RefSeqiNP_418050.1. NC_000913.3.
WP_000015300.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76617; AAC76617; b3593.
BAE77700; BAE77700; BAE77700.
GeneIDi948120.
KEGGiecj:JW3566.
eco:b3593.
PATRICi32122666. VBIEscCol129921_3710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L19044 Genomic DNA. Translation: AAC95065.1.
U00039 Genomic DNA. Translation: AAB18570.1.
U00096 Genomic DNA. Translation: AAC76617.1.
AP009048 Genomic DNA. Translation: BAE77700.1.
PIRiC65159.
RefSeqiNP_418050.1. NC_000913.3.
WP_000015300.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP16916.
SMRiP16916.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262562. 134 interactors.
DIPiDIP-10699N.
IntActiP16916. 27 interactors.
MINTiMINT-1242055.
STRINGi511145.b3593.

Proteomic databases

PaxDbiP16916.
PRIDEiP16916.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76617; AAC76617; b3593.
BAE77700; BAE77700; BAE77700.
GeneIDi948120.
KEGGiecj:JW3566.
eco:b3593.
PATRICi32122666. VBIEscCol129921_3710.

Organism-specific databases

EchoBASEiEB0839.
EcoGeneiEG10846. rhsA.

Phylogenomic databases

eggNOGiENOG4105CNA. Bacteria.
COG3209. LUCA.
HOGENOMiHOG000225201.
InParanoidiP16916.
OMAiERYYYSW.
PhylomeDBiP16916.

Enzyme and pathway databases

BioCyciEcoCyc:EG10846-MONOMER.
ECOL316407:JW3566-MONOMER.

Miscellaneous databases

PROiP16916.

Family and domain databases

InterProiIPR028947. Ntox34.
IPR001826. RHS.
IPR022385. Rhs_assc_core.
IPR031325. RHS_repeat.
IPR006530. YD.
[Graphical view]
PfamiPF15606. Ntox34. 1 hit.
PF03527. RHS. 1 hit.
PF05593. RHS_repeat. 7 hits.
[Graphical view]
PRINTSiPR00394. RHSPROTEIN.
TIGRFAMsiTIGR03696. Rhs_assc_core. 1 hit.
TIGR01643. YD_repeat_2x. 5 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiRHSA_ECOLI
AccessioniPrimary (citable) accession number: P16916
Secondary accession number(s): Q2M7Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: November 2, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.