P16852 (IAC17_WHEAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Alpha-amylase/trypsin inhibitor CM17 Alternative name(s): Chloroform/methanol-soluble protein CM17
Organism	Triticum aestivum (Wheat)
Taxonomic identifier	4565 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	27 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Alpha-amylase/trypsin inhibitor. It could be involved in insect defense mechanisms.
Subcellular location	Secreted.
Tissue specificity	Developing endosperm.
Miscellaneous	CM proteins would be involved in the cooking quality of pasta.
Sequence similarities	Belongs to the protease inhibitor I6 (cereal trypsin/alpha-amylase inhibitor) family. [View classification]

Ontologies

Keywords
Cellular component	Secreted
Molecular function	Alpha-amylase inhibitor Protease inhibitor Serine protease inhibitor
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	alpha-amylase inhibitor activity Inferred from electronic annotation. Source: UniProtKB-KW serine-type endopeptidase inhibitor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›27	›27	Alpha-amylase/trypsin inhibitor CM17		PRO_0000070488
Experimental info
	Non-terminal residue	27	1

Sequences

	Sequence		Length	Mass (Da)
	P16852 [UniParc]. Last modified August 1, 1990. Version 1. Checksum: 5CF533ECE20BD344	FASTA	27	3,070
	10 20 NEDCTPWTST LIXPLPXCRN YVXXQAC

References

[1]	"Evolutionary implications of sequential homologies among members of the trypsin / alpha-amylase inhibitor family (CM-proteins) in wheat and barley." Barber D., Sanchez-Monge R., Garcia-Olmedo F., Salcedo G., Mendez E. Biochim. Biophys. Acta 873:147-151(1986) Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
PIR	D25310.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	P16852.
Family and domain databases
InterPro	IPR006105. Allergen/tryp_amyl_inhib_CS. [Graphical view]
PROSITE	PS00426. CEREAL_TRYP_AMYL_INH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IAC17_WHEAT

Accession

Primary (citable) accession number: P16852

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	August 1, 1990
Last modified:	June 16, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program