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Protein

Transcriptional regulator UL34

Gene

UL34

Organism
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a transcriptional repressor of the US3 gene expression through a specific DNA sequence named the transcriptional repressive element (tre).By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator UL34
Gene namesi
Name:UL34
OrganismiHuman cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri10360 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000008992 Componenti: Genome
  • UP000008991 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001153171 – 407Transcriptional regulator UL34Add BLAST407

Proteomic databases

PRIDEiP16812.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi320 – 328Poly-Glu9

Sequence similaritiesi

Belongs to the HHV-5 UL34 protein family.Curated

Phylogenomic databases

OrthoDBiVOG090000B6.

Sequencei

Sequence statusi: Complete.

P16812-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFIITTRDF SNDDSVLRAA EMRDNVAGSI SKAYKGTVRA EGKKKLLLKH
60 70 80 90 100
LPVPPGGCSR RNSNLFVFCT ERDYRKFHQG IAQLKRAPAE LDPHEIQQVT
110 120 130 140 150
ASIRCRLQPS LREPPTPADE LQTAVSRVCA LFNQLVFTAQ LRHYCEHQDK
160 170 180 190 200
VVSYARDELT KRCGEKSALG VEVHQLVALL PHERHRELCH VLIGLLHQTP
210 220 230 240 250
HMWARSIRLI GHLRHYLQNS FLHLLMNSGL DIAQVFDGCY HSEAYRMLFQ
260 270 280 290 300
IGHTDSVSAA LELSHGAAAG PPEADENNDE GEEDDDELRH SDPAPLHESK
310 320 330 340 350
KPRNARRPRT RVPPHEQKPE ENEEEEEELF PSCKATAAFL RAEPSVSNDD
360 370 380 390 400
GNGGERCDTL ATALRHRADE EDGPLASQTA VRVAATPSPS VTPALTPVTS

PITPLCI
Length:407
Mass (Da):45,381
Last modified:February 15, 2005 - v2
Checksum:iCB66A191F3D0B70A
GO

Sequence cautioni

The sequence CAA35393 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X17403 Genomic DNA. Translation: CAA35393.1. Different initiation.
BK000394 Genomic DNA. Translation: DAA00139.1.
PIRiS09797.

Similar proteinsi

Entry informationi

Entry nameiUL34_HCMVA
AccessioniPrimary (citable) accession number: P16812
Secondary accession number(s): Q7M6P9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: February 15, 2005
Last modified: May 10, 2017
This is version 41 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families