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P16752 (UL79_HCMVA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein UL79
Gene names
Name:UL79
OrganismHuman cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) [Complete proteome]
Taxonomic identifier10360 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays a role in the expression of late transcripts bridging viral DNA replication and late gene expression during infection. Ref.6

Subcellular location

Host nucleus. Note: Localizes in replication compartments during virus infection. Ref.6

Sequence similarities

Belongs to the herpesviridae UL79 family.

Ontologies

Keywords
   Cellular componentHost nucleus
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componenthost cell nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 295295Protein UL79
PRO_0000116226

Regions

Compositional bias253 – 2564Poly-Gln

Sequences

Sequence LengthMass (Da)Tools
P16752 [UniParc].

Last modified August 1, 1990. Version 1.
Checksum: 44C9B3033F45810F

FASTA29533,845
        10         20         30         40         50         60 
MMARDEENPA VPRVRTGKFS FTCANHLILQ ISEKMSRGQP LSSLRLEELK IVRLICVLLF 

        70         80         90        100        110        120 
HRGLETLLLR ETMNNLGVSD HAVLSRKTPQ PYWPHLYREL RQAFPGLDFE AAVFDETRAA 

       130        140        150        160        170        180 
RLSQRLCHPR LSGGLLTRFV QRHTGLPVVF PEDLARNGNI LFSLGTLYGH RLFRLAAFFT 

       190        200        210        220        230        240 
RHWGAEAYEP LIRIICQKMW YFYLIGTGKM RITPDAFEIQ RSRHETGIFT FIMEDYRTFA 

       250        260        270        280        290 
GTLSRHPHRP HPQQQQHHHP GPPHPPLSHP ASSCLSPEAV LAARALHMPT LANDV 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169."
Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R., Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A., Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.
Curr. Top. Microbiol. Immunol. 154:125-169(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome."
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J., McGeoch D.J., Hayward G.S.
J. Gen. Virol. 84:17-28(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
[3]Erratum
Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J., McGeoch D.J., Hayward G.S.
J. Gen. Virol. 84:1053-1053(2003)
[4]"Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome."
Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J., Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W., Shenk T., Smith R.D., Nelson J.A.
J. Virol. 78:10960-10966(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION.
[5]Erratum
Varnum S.M., Streblow D.N., Monroe M.E., Smith P., Auberry K.J., Pasa-Tolic L., Wang D., Camp D.G. II, Rodland K., Wiley S., Britt W., Shenk T., Smith R.D., Nelson J.A.
J. Virol. 78:13395-13395(2004)
[6]"The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts."
Perng Y.C., Qian Z., Fehr A.R., Xuan B., Yu D.
J. Virol. 85:4841-4852(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X17403 Genomic DNA. Translation: CAA35352.1.
BK000394 Genomic DNA. Translation: DAA00175.1.
PIRS09842.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004290. Herpes_UL79.
[Graphical view]
PfamPF03049. Herpes_UL79. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUL79_HCMVA
AccessionPrimary (citable) accession number: P16752
Secondary accession number(s): Q7M6L3
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: April 3, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families