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P16752

- UL79_HCMVA

UniProt

P16752 - UL79_HCMVA

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Protein

Protein UL79

Gene

UL79

Organism
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Plays a role in the expression of late transcripts bridging viral DNA replication and late gene expression during infection.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Protein UL79
Gene namesi
Name:UL79
OrganismiHuman cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri10360 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000008991: Genome, UP000008992: Genome

Subcellular locationi

Host nucleus 1 Publication
Note: Localizes in replication compartments during virus infection.

GO - Cellular componenti

  1. host cell nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295Protein UL79PRO_0000116226Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP16752.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi253 – 2564Poly-Gln

Sequence similaritiesi

Belongs to the herpesviridae UL79 family.Curated

Family and domain databases

InterProiIPR004290. Herpes_UL79.
[Graphical view]
PfamiPF03049. Herpes_UL79. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P16752-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMARDEENPA VPRVRTGKFS FTCANHLILQ ISEKMSRGQP LSSLRLEELK
60 70 80 90 100
IVRLICVLLF HRGLETLLLR ETMNNLGVSD HAVLSRKTPQ PYWPHLYREL
110 120 130 140 150
RQAFPGLDFE AAVFDETRAA RLSQRLCHPR LSGGLLTRFV QRHTGLPVVF
160 170 180 190 200
PEDLARNGNI LFSLGTLYGH RLFRLAAFFT RHWGAEAYEP LIRIICQKMW
210 220 230 240 250
YFYLIGTGKM RITPDAFEIQ RSRHETGIFT FIMEDYRTFA GTLSRHPHRP
260 270 280 290
HPQQQQHHHP GPPHPPLSHP ASSCLSPEAV LAARALHMPT LANDV
Length:295
Mass (Da):33,845
Last modified:August 1, 1990 - v1
Checksum:i44C9B3033F45810F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X17403 Genomic DNA. Translation: CAA35352.1.
BK000394 Genomic DNA. Translation: DAA00175.1.
PIRiS09842.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X17403 Genomic DNA. Translation: CAA35352.1 .
BK000394 Genomic DNA. Translation: DAA00175.1 .
PIRi S09842.

3D structure databases

ProteinModelPortali P16752.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004290. Herpes_UL79.
[Graphical view ]
Pfami PF03049. Herpes_UL79. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169."
    Chee M.S., Bankier A.T., Beck S., Bohni R., Brown C.M., Cerny R., Horsnell T., Hutchison C.A. III, Kouzarides T., Martignetti J.A., Preddie E., Satchwell S.C., Tomlinson P., Weston K.M., Barrell B.G.
    Curr. Top. Microbiol. Immunol. 154:125-169(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome."
    Davison A.J., Dolan A., Akter P., Addison C., Dargan D.J., Alcendor D.J., McGeoch D.J., Hayward G.S.
    J. Gen. Virol. 84:17-28(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
  3. Cited for: IDENTIFICATION.
  4. "The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts."
    Perng Y.C., Qian Z., Fehr A.R., Xuan B., Yu D.
    J. Virol. 85:4841-4852(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiUL79_HCMVA
AccessioniPrimary (citable) accession number: P16752
Secondary accession number(s): Q7M6L3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 29, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3