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Protein

Mannan endo-1,4-beta-mannosidase A and B

Gene
N/A
Organism
Bacillus mannanilyticus (strain DSM 16130 / JCM 10596 / AM-001)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.

GO - Molecular functioni

  1. cellulase activity Source: InterPro
  2. mannan endo-1,4-beta-mannosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. substituted mannan metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiCBM59. Carbohydrate-Binding Module Family 59.
GH26. Glycoside Hydrolase Family 26.

Names & Taxonomyi

Protein namesi
Recommended name:
Mannan endo-1,4-beta-mannosidase A and B (EC:3.2.1.78)
Alternative name(s):
Beta-mannanase
Endo-1,4-mannanase
Cleaved into the following 2 chains:
OrganismiBacillus mannanilyticus (strain DSM 16130 / JCM 10596 / AM-001)
Taxonomic identifieri1236954 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2626Add
BLAST
Chaini27 – 513487Mannan endo-1,4-beta-mannosidase APRO_0000012169Add
BLAST
Chaini27 – 365339Mannan endo-1,4-beta-mannosidase BPRO_0000012170Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP16699.
SMRiP16699. Positions 33-363.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 26 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR022790. EndoGluc_H/Glyco_hydro_26.
IPR008979. Galactose-bd-like.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P16699-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVYKKVAFV MAFIMFFSVL PTISMSSEAN GAALSNPNAN QTTKNVYSWL
60 70 80 90 100
ANLPNKSNKR VVSGHFGGYS DSTLAWIKQC ARELTGKMPG ILSCDYKNWQ
110 120 130 140 150
TRLYVADQIS YGCNQELINF WNQGGLVTIS VHMPNPGFHS GENYKTILPT
160 170 180 190 200
SQFQNLTNHR TTEGRRWKDM LDKMADGLDE LQNNGVTVLF RPLHEMNGEW
210 220 230 240 250
FWWGAEGYNQ FDQTRANAYI SAWRDMYQYF THERKLNNLI WVYSPDVYRD
260 270 280 290 300
HVTSYYPGAN YVDIVALDSY HPDPHSLTDQ YNRMIALDKP FAFAEIGPPE
310 320 330 340 350
SMAGSFDYSN YIQAIKQKYP RTVYFLAWND KWSPHNNRGA WDLFNDSWVV
360 370 380 390 400
NRGEIDYGQS NPATVLYDFE NNTLSWSGCE FTDGGPWTSN EWSANGTQSL
410 420 430 440 450
KADVVLGNNS YHLQKTVNRN LSSFKNLEIK VSHSSWGNVG SGMTARVFVK
460 470 480 490 500
TGSAWRWNAG EFCQFAGKRT TALSIDLTKV SNLHDVREIG VEYKAPANSN
510
GKTAIYLDHV TVR
Length:513
Mass (Da):58,430
Last modified:August 1, 1990 - v1
Checksum:i88D105F622CDB5A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31797 Genomic DNA. Translation: AAA22586.1.
PIRiA37219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M31797 Genomic DNA. Translation: AAA22586.1.
PIRiA37219.

3D structure databases

ProteinModelPortaliP16699.
SMRiP16699. Positions 33-363.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM59. Carbohydrate-Binding Module Family 59.
GH26. Glycoside Hydrolase Family 26.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR022790. EndoGluc_H/Glyco_hydro_26.
IPR008979. Galactose-bd-like.
IPR000805. Glyco_hydro_26.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02156. Glyco_hydro_26. 1 hit.
[Graphical view]
PRINTSiPR00739. GLHYDRLASE26.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Two Bacillus beta-mannanases having different COOH termini are produced in Escherichia coli carrying pMAH5."
    Akino T., Kato C., Horikoshi K.
    Appl. Environ. Microbiol. 55:3178-3183(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.

Entry informationi

Entry nameiMANB_BACMA
AccessioniPrimary (citable) accession number: P16699
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 1, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.