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Protein

Putative phosphonates utilization ATP-binding protein PhnK

Gene

phnK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 45ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • organic phosphonate catabolic process Source: EcoCyc

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:PHNK-MONOMER
MetaCyc:PHNK-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphonates utilization ATP-binding protein PhnK
Gene namesi
Name:phnK
Ordered Locus Names:b4097, JW5727
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10720 phnK

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000927441 – 252Putative phosphonates utilization ATP-binding protein PhnKAdd BLAST252

Proteomic databases

PaxDbiP16678
PRIDEiP16678

Interactioni

Subunit structurei

Forms a complex with PhnG, PhnH, PhnI and PhnJ with the suggested composition PhnG4H2I2J2K.1 Publication

Protein-protein interaction databases

BioGridi4262020, 12 interactors
DIPiDIP-10490N
IntActiP16678, 6 interactors
STRINGi316385.ECDH10B_4288

Structurei

3D structure databases

ProteinModelPortaliP16678
SMRiP16678
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 246ABC transporterPROSITE-ProRule annotationAdd BLAST241

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Phylogenomic databases

eggNOGiENOG4105ENV Bacteria
COG4107 LUCA
InParanoidiP16678
KOiK05781
OMAiDWGFVRQ
PhylomeDBiP16678

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR012700 CP_lyase_PhnK
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PIRSFiPIRSF037116 CP_lyase_PhnK, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR02323 CP_lyasePhnK, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P16678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQPLLSVNN LTHLYAPGKG FSDVSFDLWP GEVLGIVGES GSGKTTLLKS
60 70 80 90 100
ISARLTPQQG EIHYENRSLY AMSEADRRRL LRTEWGVVHQ HPLDGLRRQV
110 120 130 140 150
SAGGNIGERL MATGARHYGD IRATAQKWLE EVEIPANRID DLPTTFSGGM
160 170 180 190 200
QQRLQIARNL VTHPKLVFMD EPTGGLDVSV QARLLDLLRG LVVELNLAVV
210 220 230 240 250
IVTHDLGVAR LLADRLLVMK QGQVVESGLT DRVLDDPHHP YTQLLVSSVL

QN
Length:252
Mass (Da):27,831
Last modified:August 1, 1990 - v1
Checksum:i3B8677F22C472A9F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti47L → Q in AAA96996 (PubMed:7610040).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05260 Genomic DNA Translation: AAA24349.1
D90227 Genomic DNA Translation: BAA14271.1
U14003 Genomic DNA Translation: AAA96996.1
U00096 Genomic DNA Translation: AAT48240.1
AP009048 Genomic DNA Translation: BAE78100.1
PIRiS56325
RefSeqiWP_001075514.1, NZ_LN832404.1
YP_026282.1, NC_000913.3

Genome annotation databases

EnsemblBacteriaiAAT48240; AAT48240; b4097
BAE78100; BAE78100; BAE78100
GeneIDi948611
KEGGiecj:JW5727
eco:b4097
PATRICifig|1411691.4.peg.2603

Similar proteinsi

Entry informationi

Entry nameiPHNK_ECOLI
AccessioniPrimary (citable) accession number: P16678
Secondary accession number(s): Q2M6K6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: March 28, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health