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Protein

Antigen TpF1

Gene

tpf1

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play an important structural role in the outer membrane.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Antigen TpF1
Alternative name(s):
Antigen 4D
Antigen C1-5
Gene namesi
Name:tpf1
Ordered Locus Names:TP_1038
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00002016642 – 177Antigen TpF1Add BLAST176

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Homodecamer; either linked or stabilized by disulfide bonds.

Protein-protein interaction databases

IntActiP16665. 3 interactors.
STRINGi243276.TP1038.

Structurei

Secondary structure

1177
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi29 – 59Combined sources31
Beta strandi60 – 62Combined sources3
Helixi65 – 92Combined sources28
Helixi101 – 107Combined sources7
Beta strandi117 – 119Combined sources3
Helixi120 – 147Combined sources28
Helixi151 – 175Combined sources25

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FJCX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P22-177[»]
ProteinModelPortaliP16665.
SMRiP16665.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP16665.

Family & Domainsi

Sequence similaritiesi

Belongs to the Dps family.Curated

Phylogenomic databases

eggNOGiENOG4108RMU. Bacteria.
COG0783. LUCA.
KOiK04047.
OMAiPLHAYSD.

Family and domain databases

CDDicd01043. DPS. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
InterProiIPR002177. DPS_DNA-bd.
IPR023188. DPS_DNA-bd_CS.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
PIRSFiPIRSF005900. Dps. 1 hit.
PRINTSiPR01346. HELNAPAPROT.
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00818. DPS_1. 1 hit.
PS00819. DPS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P16665-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMCTDGKKY HSTATSAAVG ASAPGVPDAR AIAAICEQLR QHVADLGVLY
60 70 80 90 100
IKLHNYHWHI YGIEFKQVHE LLEEYYVSVT EAFDTIAERL LQLGAQAPAS
110 120 130 140 150
MAEYLALSGI AEETEKEITI VSALARVKRD FEYLSTRFSQ TQVLAAESGD
160 170
AVTDGIITDI LRTLGKAIWM LGATLKA
Length:177
Mass (Da):19,361
Last modified:January 23, 2007 - v2
Checksum:iA0E0855069566773
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32401 Genomic DNA. No translation available.
AE000520 Genomic DNA. Translation: AAC26592.1.
PIRiJS0097.
RefSeqiWP_010882482.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC26592; AAC26592; TP_1038.
GeneIDi2610937.
KEGGitpa:TP_1038.
PATRICi20532207. VBITrePal57110_1096.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M32401 Genomic DNA. No translation available.
AE000520 Genomic DNA. Translation: AAC26592.1.
PIRiJS0097.
RefSeqiWP_010882482.1. NC_021490.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FJCX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P22-177[»]
ProteinModelPortaliP16665.
SMRiP16665.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP16665. 3 interactors.
STRINGi243276.TP1038.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC26592; AAC26592; TP_1038.
GeneIDi2610937.
KEGGitpa:TP_1038.
PATRICi20532207. VBITrePal57110_1096.

Phylogenomic databases

eggNOGiENOG4108RMU. Bacteria.
COG0783. LUCA.
KOiK04047.
OMAiPLHAYSD.

Miscellaneous databases

EvolutionaryTraceiP16665.

Family and domain databases

CDDicd01043. DPS. 1 hit.
Gene3Di1.20.1260.10. 1 hit.
InterProiIPR002177. DPS_DNA-bd.
IPR023188. DPS_DNA-bd_CS.
IPR009078. Ferritin-like_SF.
IPR012347. Ferritin-rel.
IPR008331. Ferritin_DPS_dom.
[Graphical view]
PfamiPF00210. Ferritin. 1 hit.
[Graphical view]
PIRSFiPIRSF005900. Dps. 1 hit.
PRINTSiPR01346. HELNAPAPROT.
SUPFAMiSSF47240. SSF47240. 1 hit.
PROSITEiPS00818. DPS_1. 1 hit.
PS00819. DPS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTPF1_TREPA
AccessioniPrimary (citable) accession number: P16665
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.