Reviewed, UniProtKB/Swiss-Prot P16630 (GUNS_PECCC)

Names and origin

Protein names

Recommended name:
    Endoglucanase S
    EC=3.2.1.4
Alternative name(s):
    Endo-1,4-beta-glucanase S
    Cellulase S

Gene names

Name:

celS

Organism

Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora)

Taxonomic identifier

555 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
Sequence similarities	Belongs to the glycosyl hydrolase 12 (cellulase H) family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cellulose degradation Polysaccharide degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	cellulase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32
	Chain	33 – 264	232	Endoglucanase S		PRO_0000008020

Sequences

	Sequence		Length	Mass (Da)
	P16630-1 [UniParc]. Last modified August 1, 1990. Version 1. Checksum: E6D61388950C77AA	FASTA	264	29,757
	10 20 30 40 50 60 MQTVNTQPHR IFRVLLPAVF SSLLLSSLTV SAASSSNDAD KLYFGNNKYY LFNNVWGKDE 70 80 90 100 110 120 IKGWQQTIFY NSPISMGWNW HWPSSTHSVK AYPSLVSGWH WTAGYTENSG LPIQLSSNKS 130 140 150 160 170 180 ITSNVTYSIK ATGTYNAAYD IWFHTTDKAN WDSSPTDELM IWLNDTNAGP AGDYIETVFL 190 200 210 220 230 240 GDSSWNVFKG WINADNGGGW NVFSFVHTSG TNSASLNIRH FTDYLVQTKQ WMSDEKYISS 250 260 VEFGTEIFGG DGQIDITEWR VDVK

References

[1]	"CelS: a novel endoglucanase identified from Erwinia carotovora subsp. carotovora." Saarilahti H.T., Henrissat B., Palva E.T. Gene 90:9-14(1990) [PubMed: 2379837] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE. Strain: SCC3193.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M32399 Genomic DNA. Translation: AAA24817.1.
PIR	JU0328.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH12. Glycoside Hydrolase Family 12.
Enzyme and pathway databases
BRENDA	3.2.1.4. 290410.
Family and domain databases
InterPro	IPR013319. Glyco_hydro_11/12_cat. IPR002594. Glyco_hydro_12. [Graphical view]
Gene3D	G3DSA:2.60.120.180. Glyco_hydro_11/12_cat. 1 hit.
Pfam	PF01670. Glyco_hydro_12. 1 hit. [Graphical view]
ProDom	PD004316. Glyco_hydro_12. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

GUNS_PECCC

Accession

Primary (citable) accession number: P16630

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	August 1, 1990
Last modified:	June 16, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)