Reviewed, UniProtKB/Swiss-Prot P16548 (A95EF_DROME)

Names and origin

Protein names

Recommended name:
    Accessory gland-specific peptide 95EF
Alternative name(s):
    Male accessory gland secretory protein 316

Gene names

Name:	Acp95EF
Synonyms:	MSP316, Mst95E
ORF Names:	CG17924

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	52 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	This protein may be a precursor of secreted proteins and peptide hormones. Ref.1
Subcellular location	Secreted.
Tissue specificity	Main cells of the accessory glands of males. Ref.1
Developmental stage	In very late pupae and in adults. Ref.1
Induction	By mating. Ref.1

Ontologies

Keywords
Biological process	Behavior
Cellular component	Secreted
Domain	Signal
Molecular function	Hormone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	behavior Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	hormone activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
	Q9VFU0	1	EBI-172755,EBI-121137
	Q9W4P4	1	EBI-172755,EBI-143481

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Peptide	23 – 52	30	Accessory gland-specific peptide 95EF		PRO_0000020590
Experimental info
	Sequence conflict	20	1	T → S in AAD13400. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P16548-1 [UniParc]. Last modified October 18, 2001. Version 2. Checksum: A44008BD6057FF2B	FASTA	52	5,405
	10 20 30 40 50 MASVKLFFIA ILVVALSLNT SAAVLNPSST AKPRFETKDR KLSAGALQSL AG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structure, cell-specific expression, and mating-induced regulation of a Drosophila melanogaster male accessory gland gene." Dibenedetto A.J., Harada H.A., Wolfner M.F. Dev. Biol. 139:134-148(1990) [PubMed: 2109712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, INDUCTION. Strain: Canton-S.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION.
[4]	Stapleton M., Carlson J.W., Frise E., Kapadia B., Park S., Wan K.H., Yu C., Celniker S.E. Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M32022 Genomic DNA. Translation: AAD13400.1. AE014297 Genomic DNA. Translation: AAF56263.2. BT030959 mRNA. Translation: ABV82341.1. Different initiation. BT030982 mRNA. Translation: ABV82364.2. Different initiation.
PIR	A37354.
RefSeq	NP_524898.1.
UniGene	Dm.31275
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:20377N.
IntAct	P16548. 4 interactions.
STRING	P16548.
Genome annotation databases
Ensembl	FBtr0084561; FBpp0083946; FBgn0002863; Drosophila melanogaster. [Genome view]
GeneID	47852.
KEGG	dme:Dmel_CG17924.
NMPDR	fig|7227.3.peg.14404.
Organism-specific databases
CTD	47852.
FlyBase	FBgn0002863. Acp95EF.
Phylogenomic databases
OrthoDB	EOG9FN4QV
Enzyme and pathway databases
BioCyc	DMEL-XXX-02:DMEL-XXX-02-013148-MON.
Gene expression databases
GermOnline	CG17924. Drosophila melanogaster.
Family and domain databases
ProtoNet	Search...
Other Resources
NextBio	839152.

Entry information

Entry name

A95EF_DROME

Accession

Primary (citable) accession number: P16548
Secondary accession number(s): A8E717, A8E740, Q9VCB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	October 18, 2001
Last modified:	November 24, 2009
This is version 83 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project