P16494 (NSS_BUNYW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Non-structural protein NS-S

Gene names

Name:

N

Organism

Bunyamwera virus (BUNV) [Reference proteome]

Taxonomic identifier

35304 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA negative-strand viruses › Bunyaviridae › Orthobunyavirus

Virus host

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) [TaxID: 7159]
Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the orthobunyavirus NS-S protein family.

Ontologies

Keywords
Biological process	Host gene expression shutoff by virus Host transcription shutoff by virus Host-virus interaction Inhibition of host RNA polymerase II by virus
Coding sequence diversity	Alternative initiation
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	suppression by virus of host RNA polymerase II activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative initiation. [Align] [Select]

Isoform NSS (identifier: P16494-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: Produced by alternative initiation in the N gene, but encoded on another frame.

Isoform N (identifier: P16495-1)

The sequence of this isoform can be found in the external entry P16495.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 101	101	Non-structural protein NS-S		PRO_0000221976

Sequences

	Sequence		Length	Mass (Da)
	Isoform NSS [UniParc]. Last modified August 1, 1990. Version 1. Checksum: 823C9F75448C6368	FASTA	101	11,024
	10 20 30 40 50 60 MMSLLTPAVL LTQRSHTLTL SVSTPLGLVM TTYESSTLKD ARLKLVSQKE VNGKLHLTLG 70 80 90 100 AGRLLYIIRI FLATGTTQFL TMVLPSTASV DSLPGTYLRR C
	Isoform N [UniParc]. See P16495.		–	–

References

[1]	"Nucleotide sequence analysis of the small (S) RNA segment of Bunyamwera virus, the prototype of the family Bunyaviridae." Elliott R.M. J. Gen. Virol. 70:1281-1285(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	D00353 Genomic RNA. Translation: BAA00262.1.
PIR	MNVUBV. B31365.
RefSeq	NP_047214.1. NC_001927.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2648218.
Family and domain databases
InterPro	IPR000797. Bunya_NSs. [Graphical view]
Pfam	PF01104. Bunya_NS-S. 1 hit. [Graphical view]
PIRSF	PIRSF003954. NS-S_OrthobunV. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NSS_BUNYW

Accession

Primary (citable) accession number: P16494

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1990
Last sequence update:	August 1, 1990
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program