##gff-version 3
P16455	UniProtKB	Chain	1	207	.	.	.	ID=PRO_0000139359;Note=Methylated-DNA--protein-cysteine methyltransferase	
P16455	UniProtKB	Active site	145	145	.	.	.	Note=Nucleophile%3B methyl group acceptor	
P16455	UniProtKB	Binding site	5	5	.	.	.	.	
P16455	UniProtKB	Binding site	24	24	.	.	.	.	
P16455	UniProtKB	Binding site	29	29	.	.	.	.	
P16455	UniProtKB	Binding site	85	85	.	.	.	.	
P16455	UniProtKB	Binding site	95	95	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Binding site	114	114	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Binding site	115	115	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Binding site	123	123	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Binding site	128	128	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Binding site	151	151	.	.	.	Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:15964013;Dbxref=PMID:10747039,PMID:15964013	
P16455	UniProtKB	Modified residue	14	14	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
P16455	UniProtKB	Modified residue	201	201	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:23186163,ECO:0007744|PubMed:24275569;Dbxref=PMID:23186163,PMID:24275569	
P16455	UniProtKB	Natural variant	30	30	.	.	.	ID=VAR_014750;Note=E->K;Dbxref=dbSNP:rs2020893	
P16455	UniProtKB	Natural variant	53	53	.	.	.	ID=VAR_056129;Note=L->F;Dbxref=dbSNP:rs12917	
P16455	UniProtKB	Natural variant	58	58	.	.	.	ID=VAR_029112;Note=P->S;Dbxref=dbSNP:rs2308322	
P16455	UniProtKB	Natural variant	65	65	.	.	.	ID=VAR_020354;Note=W->C;Dbxref=dbSNP:rs2282164	
P16455	UniProtKB	Natural variant	84	84	.	.	.	ID=VAR_014751;Note=L->F;Dbxref=dbSNP:rs12917	
P16455	UniProtKB	Natural variant	112	112	.	.	.	ID=VAR_056130;Note=I->V;Dbxref=dbSNP:rs2308321	
P16455	UniProtKB	Natural variant	143	143	.	.	.	ID=VAR_014752;Note=I->V;Dbxref=dbSNP:rs2308321	
P16455	UniProtKB	Natural variant	160	160	.	.	.	ID=VAR_014753;Note=G->R;Dbxref=dbSNP:rs2308318	
P16455	UniProtKB	Natural variant	166	166	.	.	.	ID=VAR_014754;Note=E->D;Dbxref=dbSNP:rs2308320	
P16455	UniProtKB	Natural variant	178	178	.	.	.	ID=VAR_014755;Note=K->R;Dbxref=dbSNP:rs2308327	
P16455	UniProtKB	Mutagenesis	114	114	.	.	.	Note=Decreases activity towards methylated DNA over 1000-fold. Slightly reduced reactivity with O6-benzylguanine. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7766621;Dbxref=PMID:7766621	
P16455	UniProtKB	Mutagenesis	114	114	.	.	.	Note=Loss of DNA repair activity. Slightly reduced reactivity with O6-benzylguanine. Y->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7766621;Dbxref=PMID:7766621	
P16455	UniProtKB	Mutagenesis	128	128	.	.	.	Note=Decreases activity towards methylated DNA over 1000-fold. No effect on reactivity with O6-benzylguanine. R->A%2CD;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:7766621;Dbxref=PMID:10747039,PMID:7766621	
P16455	UniProtKB	Mutagenesis	128	128	.	.	.	Note=Loss of DNA repair activity. R->G;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:7766621;Dbxref=PMID:10747039,PMID:7766621	
P16455	UniProtKB	Mutagenesis	128	128	.	.	.	Note=Slightly reduced DNA repair activity. R->K%2CL;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:7766621;Dbxref=PMID:10747039,PMID:7766621	
P16455	UniProtKB	Mutagenesis	138	138	.	.	.	Note=Decreased reactivity with O6-benzylguanine. P->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7954470;Dbxref=PMID:7954470	
P16455	UniProtKB	Mutagenesis	140	140	.	.	.	Note=Decreased reactivity with O6-benzylguanine. P->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7954470;Dbxref=PMID:7954470	
P16455	UniProtKB	Mutagenesis	145	145	.	.	.	Note=Loss of DNA repair activity. C->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:10747039,ECO:0000269|PubMed:7766621;Dbxref=PMID:10747039,PMID:7766621	
P16455	UniProtKB	Mutagenesis	156	156	.	.	.	Note=Decreased reactivity with O6-benzylguanine. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7954470;Dbxref=PMID:7954470	
P16455	UniProtKB	Mutagenesis	158	158	.	.	.	Note=Reduced DNA repair activity. Decreased reactivity with O6-benzylguanine. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7614699;Dbxref=PMID:7614699	
P16455	UniProtKB	Mutagenesis	158	158	.	.	.	Note=Slightly reduced DNA repair activity. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7614699;Dbxref=PMID:7614699	
P16455	UniProtKB	Sequence conflict	127	127	.	.	.	Note=A->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P16455	UniProtKB	Beta strand	8	12	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Beta strand	19	24	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Beta strand	27	33	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Beta strand	50	52	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1EH6	
P16455	UniProtKB	Helix	57	71	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	73	78	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	87	90	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	94	105	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	114	120	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Turn	124	126	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1T38	
P16455	UniProtKB	Helix	127	134	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Beta strand	138	140	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	145	147	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT	
P16455	UniProtKB	Helix	162	171	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1QNT