Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lectin

Gene
N/A
Organism
Erythrina corallodendron (Coral tree)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Galactose and N-acetyllactosamine specific lectin. Binds to the H-2 blood type determinant fucosyl-N-acetyllactosamine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Calcium, Lectin

Names & Taxonomyi

Protein namesi
Recommended name:
Lectin
Alternative name(s):
ECorL
OrganismiErythrina corallodendron (Coral tree)
Taxonomic identifieri3843 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeErythrina

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 26262 PublicationsAdd
BLAST
Chaini27 – 268242LectinPRO_0000017617Add
BLAST
Propeptidei269 – 28113PRO_0000017618Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi43 – 431N-linked (GlcNAc...)1 Publication
Glycosylationi139 – 1391N-linked (GlcNAc...)1 Publication

Post-translational modificationi

A minor C-terminal proteolytic processing site is observed at position 268.1 Publication

Keywords - PTMi

Glycoprotein

PTM databases

UniCarbKBiP16404.

Interactioni

Subunit structurei

Homodimer.

Structurei

Secondary structure

1
281
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi28 – 369Combined sources
Beta strandi42 – 487Combined sources
Beta strandi58 – 614Combined sources
Beta strandi67 – 693Combined sources
Beta strandi74 – 818Combined sources
Turni88 – 903Combined sources
Beta strandi95 – 1039Combined sources
Beta strandi109 – 1113Combined sources
Beta strandi115 – 1239Combined sources
Helixi132 – 1343Combined sources
Turni135 – 1373Combined sources
Beta strandi138 – 1425Combined sources
Helixi145 – 1473Combined sources
Beta strandi150 – 1556Combined sources
Beta strandi166 – 17712Combined sources
Beta strandi179 – 1835Combined sources
Beta strandi192 – 1998Combined sources
Turni200 – 2034Combined sources
Beta strandi204 – 2107Combined sources
Turni212 – 2143Combined sources
Beta strandi217 – 2237Combined sources
Helixi226 – 2283Combined sources
Beta strandi232 – 24211Combined sources
Beta strandi253 – 26311Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AX0X-ray1.90A27-265[»]
1AX1X-ray1.95A27-265[»]
1AX2X-ray1.95A27-265[»]
1AXYX-ray1.95A27-265[»]
1AXZX-ray1.95A27-265[»]
1FYUX-ray2.60A/B27-281[»]
1LTEX-ray2.00A27-265[»]
1SFYX-ray2.55A/B/C/D/E/F27-265[»]
3N35X-ray2.00A27-268[»]
3N36X-ray2.30A27-268[»]
3N3HX-ray2.00A27-268[»]
ProteinModelPortaliP16404.
SMRiP16404. Positions 27-265.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP16404.

Family & Domainsi

Sequence similaritiesi

Belongs to the leguminous lectin family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR016363. L-lectin.
IPR000985. Lectin_LegA_CS.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
[Graphical view]
PIRSFiPIRSF002690. L-type_lectin_plant. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00308. LECTIN_LEGUME_ALPHA. 1 hit.
PS00307. LECTIN_LEGUME_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P16404-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATYKLCSVL ALSLTLFLLI LNKVNSVETI SFSFSEFEPG NDNLTLQGAA
60 70 80 90 100
LITQSGVLQL TKINQNGMPA WDSTGRTLYA KPVHIWDMTT GTVASFETRF
110 120 130 140 150
SFSIEQPYTR PLPADGLVFF MGPTKSKPAQ GYGYLGIFNN SKQDNSYQTL
160 170 180 190 200
GVEFDTFSNP WDPPQVPHIG IDVNSIRSIK TQPFQLDNGQ VANVVIKYDA
210 220 230 240 250
SSKILHAVLV YPSSGAIYTI AEIVDVKQVL PEWVDVGLSG ATGAQRDAAE
260 270 280
THDVYSWSFQ ASLPETNDAV IPTSNHNTFA I
Length:281
Mass (Da):30,752
Last modified:July 15, 1998 - v3
Checksum:i311DE5A43AEF1E67
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti49 – 546AALITQ → DSIPET AA sequence (PubMed:2806566).Curated
Sequence conflicti139 – 1391N → F AA sequence (PubMed:2806566).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti48 – 481G → A.
Natural varianti160 – 1601P → Q.1 Publication
Natural varianti225 – 2251D → V.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52782 mRNA. Translation: CAA36986.1.
PIRiS09697.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52782 mRNA. Translation: CAA36986.1.
PIRiS09697.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AX0X-ray1.90A27-265[»]
1AX1X-ray1.95A27-265[»]
1AX2X-ray1.95A27-265[»]
1AXYX-ray1.95A27-265[»]
1AXZX-ray1.95A27-265[»]
1FYUX-ray2.60A/B27-281[»]
1LTEX-ray2.00A27-265[»]
1SFYX-ray2.55A/B/C/D/E/F27-265[»]
3N35X-ray2.00A27-268[»]
3N36X-ray2.30A27-268[»]
3N3HX-ray2.00A27-268[»]
ProteinModelPortaliP16404.
SMRiP16404. Positions 27-265.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

UniCarbKBiP16404.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP16404.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR016363. L-lectin.
IPR000985. Lectin_LegA_CS.
IPR019825. Lectin_legB_Mn/Ca_BS.
IPR001220. Legume_lectin_dom.
[Graphical view]
PfamiPF00139. Lectin_legB. 1 hit.
[Graphical view]
PIRSFiPIRSF002690. L-type_lectin_plant. 1 hit.
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS00308. LECTIN_LEGUME_ALPHA. 1 hit.
PS00307. LECTIN_LEGUME_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLEC_ERYCO
AccessioniPrimary (citable) accession number: P16404
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: July 15, 1998
Last modified: June 8, 2016
This is version 101 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Binds one manganese (or another transition metal) ion and one calcium ion.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.