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P16344

- VKT4_HETCR

UniProt

P16344 - VKT4_HETCR

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Protein

Kunitz-type trypsin inhibitor IV

Gene
N/A
Organism
Heteractis crispa (Leathery sea anemone) (Radianthus macrodactylus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Inhibitor of trypsin.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei14 – 152Reactive bondBy similarity

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI02.061.

Names & Taxonomyi

Protein namesi
Recommended name:
Kunitz-type trypsin inhibitor IV
OrganismiHeteractis crispa (Leathery sea anemone) (Radianthus macrodactylus)
Taxonomic identifieri175771 [NCBI]
Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaStichodactylidaeHeteractis

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
  2. nematocyst Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nematocyst, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 5656Kunitz-type trypsin inhibitor IVPRO_0000155418Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi4 ↔ 54PROSITE-ProRule annotation
Disulfide bondi13 ↔ 37PROSITE-ProRule annotation
Disulfide bondi29 ↔ 50PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP16344.
SMRiP16344. Positions 2-56.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 5451BPTI/Kunitz inhibitorPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 BPTI/Kunitz inhibitor domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di4.10.410.10. 1 hit.
InterProiIPR002223. Prot_inh_Kunz-m.
[Graphical view]
PfamiPF00014. Kunitz_BPTI. 1 hit.
[Graphical view]
PRINTSiPR00759. BASICPTASE.
SMARTiSM00131. KU. 1 hit.
[Graphical view]
SUPFAMiSSF57362. SSF57362. 1 hit.
PROSITEiPS50279. BPTI_KUNITZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P16344-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
GSICLEPKVV GPCTAYFPRF YFDSETGKCT PFIYGGCEGN SYVDEKLHAC

RAICRA
Length:56
Mass (Da):6,172
Last modified:August 1, 1990 - v1
Checksum:i68374D2025B841C0
GO

Sequence databases

PIRiJN0380.

Cross-referencesi

Sequence databases

PIRi JN0380.

3D structure databases

ProteinModelPortali P16344.
SMRi P16344. Positions 2-56.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I02.061.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 4.10.410.10. 1 hit.
InterProi IPR002223. Prot_inh_Kunz-m.
[Graphical view ]
Pfami PF00014. Kunitz_BPTI. 1 hit.
[Graphical view ]
PRINTSi PR00759. BASICPTASE.
SMARTi SM00131. KU. 1 hit.
[Graphical view ]
SUPFAMi SSF57362. SSF57362. 1 hit.
PROSITEi PS50279. BPTI_KUNITZ_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Amino-acid sequence of trypsin inhibitor IV from Radiantis macrodactylus."
    Zykova T.A., Vinokurov L.M., Markova L.F., Kozlovskaya E.P., Elyakov G.B.
    Bioorg. Khim. 11:293-301(1985)
    Cited for: PROTEIN SEQUENCE.

Entry informationi

Entry nameiVKT4_HETCR
AccessioniPrimary (citable) accession number: P16344
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3