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P16344

- VKT4_HETCR

UniProt

P16344 - VKT4_HETCR

Protein

Kunitz-type trypsin inhibitor IV

Gene
N/A
Organism
Heteractis crispa (Leathery sea anemone) (Radianthus macrodactylus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Inhibitor of trypsin.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei14 – 152Reactive bondBy similarity

    GO - Molecular functioni

    1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Protease inhibitor, Serine protease inhibitor

    Protein family/group databases

    MEROPSiI02.061.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Kunitz-type trypsin inhibitor IV
    OrganismiHeteractis crispa (Leathery sea anemone) (Radianthus macrodactylus)
    Taxonomic identifieri175771 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaStichodactylidaeHeteractis

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell
    2. nematocyst Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nematocyst, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 5656Kunitz-type trypsin inhibitor IVPRO_0000155418Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi4 ↔ 54PROSITE-ProRule annotation
    Disulfide bondi13 ↔ 37PROSITE-ProRule annotation
    Disulfide bondi29 ↔ 50PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond

    Structurei

    3D structure databases

    ProteinModelPortaliP16344.
    SMRiP16344. Positions 2-56.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 5451BPTI/Kunitz inhibitorPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 BPTI/Kunitz inhibitor domain.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di4.10.410.10. 1 hit.
    InterProiIPR002223. Prot_inh_Kunz-m.
    [Graphical view]
    PfamiPF00014. Kunitz_BPTI. 1 hit.
    [Graphical view]
    PRINTSiPR00759. BASICPTASE.
    SMARTiSM00131. KU. 1 hit.
    [Graphical view]
    SUPFAMiSSF57362. SSF57362. 1 hit.
    PROSITEiPS50279. BPTI_KUNITZ_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P16344-1 [UniParc]FASTAAdd to Basket

    « Hide

    GSICLEPKVV GPCTAYFPRF YFDSETGKCT PFIYGGCEGN SYVDEKLHAC   50
    RAICRA 56
    Length:56
    Mass (Da):6,172
    Last modified:August 1, 1990 - v1
    Checksum:i68374D2025B841C0
    GO

    Sequence databases

    PIRiJN0380.

    Cross-referencesi

    Sequence databases

    PIRi JN0380.

    3D structure databases

    ProteinModelPortali P16344.
    SMRi P16344. Positions 2-56.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I02.061.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 4.10.410.10. 1 hit.
    InterProi IPR002223. Prot_inh_Kunz-m.
    [Graphical view ]
    Pfami PF00014. Kunitz_BPTI. 1 hit.
    [Graphical view ]
    PRINTSi PR00759. BASICPTASE.
    SMARTi SM00131. KU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57362. SSF57362. 1 hit.
    PROSITEi PS50279. BPTI_KUNITZ_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Amino-acid sequence of trypsin inhibitor IV from Radiantis macrodactylus."
      Zykova T.A., Vinokurov L.M., Markova L.F., Kozlovskaya E.P., Elyakov G.B.
      Bioorg. Khim. 11:293-301(1985)
      Cited for: PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiVKT4_HETCR
    AccessioniPrimary (citable) accession number: P16344
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1990
    Last sequence update: August 1, 1990
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3