Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P16312

- PEPT1_DERMI

UniProt

P16312 - PEPT1_DERMI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptidase 1

Gene

DERM1

Organism
Dermatophagoides microceras (House dust mite)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Thiol protease that hydrolyzes proteins, with a preference for Phe or basic residues.

Catalytic activityi

Broad endopeptidase specificity.

GO - Molecular functioni

  1. cysteine-type peptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Thiol protease

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidase 1 (EC:3.4.22.65)
Alternative name(s):
Allergen Der m I
Major mite fecal allergen Der m 1
Allergen: Der m 1
Gene namesi
Name:DERM1
OrganismiDermatophagoides microceras (House dust mite)
Taxonomic identifieri6955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataPsoroptidiaAnalgoideaPyroglyphidaeDermatophagoidinaeDermatophagoides

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei309. Der m 1.
3257. Der m 1.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – ›30›30Peptidase 1PRO_0000050547Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP16312.
SMRiP16312. Positions 1-30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Sequencei

Sequence statusi: Fragment.

P16312-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30
TQACRINSGN VPSELDLRSL RTVTPIRMQG
Length:30
Mass (Da):3,314
Last modified:August 1, 1990 - v1
Checksum:iD60B742967194886
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei30 – 301

Sequence databases

PIRiB27634.

Cross-referencesi

Sequence databases

PIRi B27634.

3D structure databases

ProteinModelPortali P16312.
SMRi P16312. Positions 1-30.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

Allergomei 309. Der m 1.
3257. Der m 1.0101.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The binding of mouse hybridoma and human IgE antibodies to the major fecal allergen, Der p I, of Dermatophagoides pteronyssinus. Relative binding site location and species specificity studied by solid-phase inhibition assays with radiolabeled antigen."
    Lind P., Hansen O.C., Horn N.
    J. Immunol. 140:4256-4262(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.

Entry informationi

Entry nameiPEPT1_DERMI
AccessioniPrimary (citable) accession number: P16312
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1990
Last sequence update: August 1, 1990
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3