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P16216

- GUN1_RUMAL

UniProt

P16216 - GUN1_RUMAL

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Protein
Endoglucanase 1
Gene
Eg I
Organism
Ruminococcus albus
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei210 – 2101Proton donor By similarity
Active sitei330 – 3301Nucleophile By similarity

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH5. Glycoside Hydrolase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 1 (EC:3.2.1.4)
Alternative name(s):
Cellulase
Endo-1,4-beta-glucanase
Endoglucanase I
Short name:
EG-I
Gene namesi
Name:Eg I
OrganismiRuminococcus albus
Taxonomic identifieri1264 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 43432 Publications
Add
BLAST
Chaini44 – 406363Endoglucanase 1
PRO_0000007871Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP16216.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P16216-1 [UniParc]FASTAAdd to Basket

« Hide

MNSKKIGAMI AAAVLSLIVM TPAATRKIVQ RQTRNSSTAV ENSAADESET    50
ENVPVSQTHT NDTMTVTSAK DLVAKMTNGW NLGNTMDATA QGLGSEVSWL 100
PLKVTTNKYM IDMLPEAGFN VLRIPVSWGN HIIDDKYTSD PAWMDRVQEI 150
VNYGIDNGLY VILNTHHEEW YMPKPSEKDG DIEEIKAVWA QIADRFKGYD 200
EHLIFEGLNE PRLRGEGAEW TGTSEAREII NEYEKAFVET VRASGGNNGD 250
RCLMITGYAA SSAYNNLSAI ELPEDSDKLI ISVHAYLPYS FALDTKGTDK 300
YDPEDTAIPE LFEHLNELFI SKGIPVIVGE FGTMNKENTE DRVKCLEDYL 350
AAAAKYDIPC VWWDNYARIG NGENFGLMNR ADLEWYFPDL IETFKTYAEK 400
DPASAE 406
Length:406
Mass (Da):45,390
Last modified:April 1, 1990 - v1
Checksum:i2E0172437B14FEA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M30928 Genomic DNA. Translation: AAA26469.1.
PIRiA43722.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M30928 Genomic DNA. Translation: AAA26469.1 .
PIRi A43722.

3D structure databases

ProteinModelPortali P16216.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.20.20.80. 1 hit.
InterProi IPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF00150. Cellulase. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure of a Ruminococcus albus endo-1,4-beta-glucanase gene."
    Ohmiya K., Kajino T., Kato A., Shimizu S.
    J. Bacteriol. 171:6771-6775(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 44-58.
    Strain: F-40.
  2. "Modification of the properties of a Ruminococcus albus endo-1,4-beta-glucanase by gene truncation."
    Ohmiya K., Deguchi H., Shimizu S.
    J. Bacteriol. 173:636-641(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 44-70.

Entry informationi

Entry nameiGUN1_RUMAL
AccessioniPrimary (citable) accession number: P16216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 16, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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