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P16216

- GUN1_RUMAL

UniProt

P16216 - GUN1_RUMAL

Protein

Endoglucanase 1

Gene

Eg I

Organism
Ruminococcus albus
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Apr 1990)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei210 – 2101Proton donorBy similarity
    Active sitei330 – 3301NucleophileBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH5. Glycoside Hydrolase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase 1 (EC:3.2.1.4)
    Alternative name(s):
    Cellulase
    Endo-1,4-beta-glucanase
    Endoglucanase I
    Short name:
    EG-I
    Gene namesi
    Name:Eg I
    OrganismiRuminococcus albus
    Taxonomic identifieri1264 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 43432 PublicationsAdd
    BLAST
    Chaini44 – 406363Endoglucanase 1PRO_0000007871Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP16216.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00150. Cellulase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P16216-1 [UniParc]FASTAAdd to Basket

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    MNSKKIGAMI AAAVLSLIVM TPAATRKIVQ RQTRNSSTAV ENSAADESET    50
    ENVPVSQTHT NDTMTVTSAK DLVAKMTNGW NLGNTMDATA QGLGSEVSWL 100
    PLKVTTNKYM IDMLPEAGFN VLRIPVSWGN HIIDDKYTSD PAWMDRVQEI 150
    VNYGIDNGLY VILNTHHEEW YMPKPSEKDG DIEEIKAVWA QIADRFKGYD 200
    EHLIFEGLNE PRLRGEGAEW TGTSEAREII NEYEKAFVET VRASGGNNGD 250
    RCLMITGYAA SSAYNNLSAI ELPEDSDKLI ISVHAYLPYS FALDTKGTDK 300
    YDPEDTAIPE LFEHLNELFI SKGIPVIVGE FGTMNKENTE DRVKCLEDYL 350
    AAAAKYDIPC VWWDNYARIG NGENFGLMNR ADLEWYFPDL IETFKTYAEK 400
    DPASAE 406
    Length:406
    Mass (Da):45,390
    Last modified:April 1, 1990 - v1
    Checksum:i2E0172437B14FEA8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M30928 Genomic DNA. Translation: AAA26469.1.
    PIRiA43722.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M30928 Genomic DNA. Translation: AAA26469.1 .
    PIRi A43722.

    3D structure databases

    ProteinModelPortali P16216.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH5. Glycoside Hydrolase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00150. Cellulase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structure of a Ruminococcus albus endo-1,4-beta-glucanase gene."
      Ohmiya K., Kajino T., Kato A., Shimizu S.
      J. Bacteriol. 171:6771-6775(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 44-58.
      Strain: F-40.
    2. "Modification of the properties of a Ruminococcus albus endo-1,4-beta-glucanase by gene truncation."
      Ohmiya K., Deguchi H., Shimizu S.
      J. Bacteriol. 173:636-641(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 44-70.

    Entry informationi

    Entry nameiGUN1_RUMAL
    AccessioniPrimary (citable) accession number: P16216
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1990
    Last sequence update: April 1, 1990
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3