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Protein

Repressor protein CI

Gene

CI

Organism
Enterobacteria phage 434 (Bacteriophage 434)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to two sets of three contiguous operator sites in the phage genome.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi18 – 3720H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Repressor protein CI
Gene namesi
Name:CI
OrganismiEnterobacteria phage 434 (Bacteriophage 434)
Taxonomic identifieri10712 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeLambdalikevirus
Virus hostiEscherichia coli [TaxID: 562]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved; by host
Chaini2 – ›95›94Repressor protein CIPRO_0000149714Add
BLAST

Interactioni

Subunit structurei

Homodimer, when bound to an operator.

Structurei

Secondary structure

1
95
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 1311Combined sources
Helixi18 – 258Combined sources
Helixi29 – 368Combined sources
Turni37 – 393Combined sources
Helixi46 – 527Combined sources
Helixi57 – 626Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PERX-ray2.50L/R2-70[»]
1PRANMR-A2-70[»]
1R63NMR-A2-64[»]
1R69X-ray2.00A2-70[»]
1RPDmodel-C/D/E/F1-95[»]
1RPEX-ray2.50L/R2-70[»]
1SQ8NMR-A11-63[»]
2OR1X-ray2.50L/R2-70[»]
2R63NMR-A2-64[»]
ProteinModelPortaliP16117.
SMRiP16117. Positions 2-70.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP16117.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 6054HTH cro/C1-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH cro/C1-type DNA-binding domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
InterProiIPR001387. Cro/C1-type_HTH.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF01381. HTH_3. 1 hit.
[Graphical view]
SMARTiSM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
PROSITEiPS50943. HTH_CROC1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

P16117-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSISSRVKSK RIQLGLNQAE LAQKVGTTQQ SIEQLENGKT KRPRFLPELA
60 70 80 90
SALGVSVDWL LNGTSDSNVR FVGHVEPKGK YPLISMVRAG SWCEA
Length:95
Mass (Da):10,426
Last modified:January 23, 2007 - v3
Checksum:i6229D2DD66EA7EFC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei95 – 951

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y00118 Genomic DNA. Translation: CAA68301.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y00118 Genomic DNA. Translation: CAA68301.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PERX-ray2.50L/R2-70[»]
1PRANMR-A2-70[»]
1R63NMR-A2-64[»]
1R69X-ray2.00A2-70[»]
1RPDmodel-C/D/E/F1-95[»]
1RPEX-ray2.50L/R2-70[»]
1SQ8NMR-A11-63[»]
2OR1X-ray2.50L/R2-70[»]
2R63NMR-A2-64[»]
ProteinModelPortaliP16117.
SMRiP16117. Positions 2-70.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP16117.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
InterProiIPR001387. Cro/C1-type_HTH.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF01381. HTH_3. 1 hit.
[Graphical view]
SMARTiSM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
PROSITEiPS50943. HTH_CROC1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPC1_BP434
AccessioniPrimary (citable) accession number: P16117
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: January 23, 2007
Last modified: May 11, 2016
This is version 101 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.