P16084 (BGLS_BUTFI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Beta-glucosidase A
EC=3.2.1.21

Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase

Gene names

Name:

bglA

Organism

Butyrivibrio fibrisolvens

Taxonomic identifier

831 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Lachnospiraceae › Butyrivibrio

Protein attributes

Sequence length	830 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	B.fibrisolvens beta-glucosidase hydrolyzes cellobiose to a limited extent, cellotriose to cellobiose and glucose, and cellotetraose and cellopentaose to predominantly glucose.
Catalytic activity	Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Cellulose degradation Polysaccharide degradation
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	cellulose catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	beta-glucosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 830	830	Beta-glucosidase A		PRO_0000210777
Sites
	Active site	769	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P16084 [UniParc]. Last modified April 1, 1990. Version 1. Checksum: 1DBF578DCA18B6F3	FASTA	830	91,852
	10 20 30 40 50 60 MEKWARIKYT PNLPLGENGE RVTASQKHIE LSCEAACEGM VLLKNDRNVL PIRKGTRVAL 70 80 90 100 110 120 FGKGVFDYVK GGGGSGDVTV PYIRNLYEGL SQYTSDISIY DKSVRFYQEY VADQYRLGIA 130 140 150 160 170 180 PGMIKEPALP EDILADAAAY ADTAIIAISR FSGEGWDRKV AGVDREIKCE AKDLVEQGNK 190 200 210 220 230 240 IFDHGDFYLT NAEKKMVKMV KENFSSVIVV MNVGGVVDTT WFKKDDQISS VLMAWQGGIE 250 260 270 280 290 300 GGLAAARILL GKVNPSGKLS DTFAARLEDY PSTEGFHEDD DYVDYTEDIY VGYRYFETIP 310 320 330 340 350 360 GAKEKVNYPF GYGLSYTTFL LEDYKAEPFV ASAADEVGKS DSDLADAIVA SVTVTNIGKI 370 380 390 400 410 420 PGKEVVQLYY SAPQGKLGKP AKVLGGYAKT RLLQPGESQR VTIALYMEDM ASYDDLGKVK 430 440 450 460 470 480 KAAWLLEKGE YHFFLGTSVR DTRLLDYTYE LSKNIIVEQV SNKLVPTSLP KRMLADGTYE 490 500 510 520 530 540 ELPQTEPVDT YATIFPRPKN WKETIEHDVL KTPVVRPQDR FQLFLPPKEG DPKKFIEVAE 550 560 570 580 590 600 CKVTLEDFIA QLSNEQLASL LGGQPNVGMA NTFGYGNLPE VGVPNAQTCD GPAGVRIAPE 610 620 630 640 650 660 VGVVTTAFPC STLLACTWNE DICYEVGVAG GEEAKECNFG AWLTPAVNIH RSPLCGRNFE 670 680 690 700 710 720 YYSEDPFLAG KQAAAMVRGI QSNNIIATPK HFALNNKESN RKGSDSRASE RAIREIYLKA 730 740 750 760 770 780 FEIIVKEQSP GASCLQYNIV NGQRSSESHD LLTGILRDEW GFEGVVVSDW WGFGEHYKEV 790 800 810 820 830 LAGNDIKMGC GYTEQLLEAI DKKALKRKDL EKRQSESSRC FSNSTKLKAA

References

[1]	"Cloning, sequencing and analysis of expression of a Butyrivibrio fibrisolvens gene encoding a beta-glucosidase." Lin L.L., Rumbak E., Zappe H., Thompson J.A., Woods D.R. J. Gen. Microbiol. 136:1567-1576(1990) [PubMed: 2262790] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: H17C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M31120 Genomic DNA. Translation: AAA23008.1.
PIR	A44768.
3D structure databases
ProteinModelPortal	P16084.
ModBase	Search...
Protein family/group databases
CAZy	GH3. Glycoside Hydrolase Family 3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR019800. Glyco_hydro_3_AS. IPR002772. Glyco_hydro_3_C. IPR001764. Glyco_hydro_3_N. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:3.40.50.1700. G3DSA:3.40.50.1700. 1 hit. G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
Pfam	PF00933. Glyco_hydro_3. 1 hit. PF01915. Glyco_hydro_3_C. 1 hit. [Graphical view]
PRINTS	PR00133. GLHYDRLASE3.
SUPFAM	SSF52279. Glyco_hydro_3_C. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BGLS_BUTFI

Accession

Primary (citable) accession number: P16084

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	May 31, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program