##gff-version 3
P16067	UniProtKB	Signal peptide	1	16	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Chain	17	1047	.	.	.	ID=PRO_0000012366;Note=Atrial natriuretic peptide receptor 2	
P16067	UniProtKB	Topological domain	17	458	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Transmembrane	459	478	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Topological domain	479	1047	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Domain	513	786	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P16067	UniProtKB	Domain	861	991	.	.	.	Note=Guanylate cyclase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00099	
P16067	UniProtKB	Modified residue	513	513	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:20977274,ECO:0000269|PubMed:9624142;Dbxref=PMID:20977274,PMID:9624142	
P16067	UniProtKB	Modified residue	516	516	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:20977274,ECO:0000269|PubMed:9624142;Dbxref=PMID:20977274,PMID:9624142	
P16067	UniProtKB	Modified residue	518	518	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:20977274,ECO:0000269|PubMed:9624142;Dbxref=PMID:20977274,PMID:9624142	
P16067	UniProtKB	Modified residue	522	522	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P16066	
P16067	UniProtKB	Modified residue	523	523	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:20977274,ECO:0000269|PubMed:9624142;Dbxref=PMID:20977274,PMID:9624142	
P16067	UniProtKB	Modified residue	526	526	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:20977274,ECO:0000269|PubMed:9624142;Dbxref=PMID:20977274,PMID:9624142	
P16067	UniProtKB	Modified residue	529	529	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:20977274;Dbxref=PMID:20977274	
P16067	UniProtKB	Glycosylation	24	24	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	35	35	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	161	161	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	195	195	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	244	244	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	277	277	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Glycosylation	349	349	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P16067	UniProtKB	Disulfide bond	75	101	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P16067	UniProtKB	Disulfide bond	439	439	.	.	.	Note=Interchain;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P16067	UniProtKB	Disulfide bond	448	448	.	.	.	Note=Interchain;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P16067	UniProtKB	Mutagenesis	513	513	.	.	.	Note=Reduced phosphorylation%2C 30%25 loss of CNP-dependent activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	516	516	.	.	.	Note=Reduced phosphorylation%2C 30%25 loss of CNP-dependent activity. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	518	518	.	.	.	Note=Reduced phosphorylation%2C 30%25 loss of CNP-dependent activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	521	521	.	.	.	Note=Reduced phosphorylation%2C 50%25 loss of CNP-dependent activity. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	522	522	.	.	.	Note=Reduced phosphorylation%2C 30%25 loss of CNP-dependent activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	523	523	.	.	.	Note=Markedly reduced phosphorylation%2C 70%25 loss of CNP-dependent activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	526	526	.	.	.	Note=Markedly reduced phosphorylation%2C 80%25 loss of CNP-dependent activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142	
P16067	UniProtKB	Mutagenesis	529	529	.	.	.	Note=No effect on phosphorylation%2C 30%25 loss of CNP-dependent activity. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9624142;Dbxref=PMID:9624142