SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P15962

- RDRP_TBSVC

UniProt

P15962 - RDRP_TBSVC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
RNA-directed RNA polymerase
Gene
ORF1
Organism
Tomato bushy stunt virus (strain Cherry) (TBSV)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNA-dependent RNA polymerase that plays an essential role in the virus replication Inferred.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. RNA-directed RNA polymerase activity Source: UniProtKB-KW
  3. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. viral RNA genome replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

Keywords - Biological processi

Viral RNA replication

Keywords - Ligandi

Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-directed RNA polymerase (EC:2.7.7.48)
Alternative name(s):
Protein p92
Cleaved into the following chain:
Gene namesi
ORF Names:ORF1
OrganismiTomato bushy stunt virus (strain Cherry) (TBSV)
Taxonomic identifieri12147 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCapsicum annuum (Bell pepper) [TaxID: 4072]
Malus [TaxID: 3749]
Pyrus (pears) [TaxID: 3766]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
Tolmiea menziesii [TaxID: 29777]
Tulipa [TaxID: 13305]
ProteomesiUP000001666: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 818818RNA-directed RNA polymerase
PRO_0000041336Add
BLAST
Chaini1 – 296296Protein p33
PRO_0000041337Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP15962.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini524 – 641118RdRp catalytic
Add
BLAST

Sequence similaritiesi

Family and domain databases

InterProiIPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
IPR013707. Tombusvirus_p33.
[Graphical view]
PfamiPF00998. RdRP_3. 1 hit.
PF08500. Tombus_P33. 1 hit.
[Graphical view]
PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P15962-1 [UniParc]FASTAAdd to Basket

« Hide

METIKRMIWP KKEIFVGDFA TGVNRTVPVN IFQLVCRVVL RYMRTGKIEC    50
DSDSMTKFIV ELLKTDCAAK WEWFMKRRQR GDYIVPLSIA SIPIIPLLSY 100
ATRVRAVSVK AFGNELSFNV RVPRPSVPKK GLLLRLAAGL ALAPICALAV 150
YATLPREKLS VFKLRTEARA HMEDEREATD CLVVEPAREL KGKDGEDLLT 200
GSRLTKVIAS TGRPRRRPYA AKIAQVARAK VGYLKNSPEN RLIYQRVMIE 250
IMDKDCVRYV DRDVILPLAI GCCFVYPDGV EESAALWGSQ ESLGVKXGGL 300
VRLPGVVTQI NRDIPSDVLL PQEVLEVRTG PPNAKDRNIF MVAGCPSQAR 350
FLVHNHCLKN LKRGLVERVF CVERNGKLAR TPQPTKGAFG RLSPFRKAVC 400
EKVGVAHRLG YDGFLSYYSG AKLRTYTRAV ESLHITPVSE RDSHLTTFVK 450
AEKISTSKGD PAPRVIQPRN PRYNVELGRY LRHMESKLMK AVDGVFGETT 500
CIKGYTADEV GAIFRAKWDR FDKPVAIGLD ASRFDQHCSV EALQYEHSFY 550
RAMYPGNKLL GKLLEWQLHN KGKGYVPDGT ITYRKEGCRM SGDINTSLGN 600
YLLMCAMVHG YMRHLGINEF SLANCGDDCV LIVERRNLKQ IQRTLPEYFL 650
NLGYTMKVEQ PVFQLEEVEF CQAHPVQFQG GWKMVRNVRT AMSKDVHCVN 700
NIRDLATRRA WSNAQHHGGL ALSAGIPVVE TFYSRFKLYD VPRKHQRIDT 750
VTNVHKWRGS GGSYVVTPES RASFWAAFGL TGDEQLALED RLERWEMDLF 800
GEEGVDAHEP SILDSAVA 818
Length:818
Mass (Da):92,253
Last modified:October 5, 2010 - v2
Checksum:iD61AD04D5F94BC42
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M21958 Genomic RNA. Translation: AAB02534.1.
M21958 Genomic RNA. Translation: AAB02535.1.
PIRiA35315. RRVGCT.
RefSeqiNP_062897.1. NC_001554.1.
NP_062898.1. NC_001554.1.

Genome annotation databases

GeneIDi1493955.
1493956.

Keywords - Coding sequence diversityi

RNA suppression of termination

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M21958 Genomic RNA. Translation: AAB02534.1 .
M21958 Genomic RNA. Translation: AAB02535.1 .
PIRi A35315. RRVGCT.
RefSeqi NP_062897.1. NC_001554.1.
NP_062898.1. NC_001554.1.

3D structure databases

ProteinModelPortali P15962.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1493955.
1493956.

Family and domain databases

InterProi IPR007094. RNA-dir_pol_PSvirus.
IPR002166. RNA_pol_HCV.
IPR013707. Tombusvirus_p33.
[Graphical view ]
Pfami PF00998. RdRP_3. 1 hit.
PF08500. Tombus_P33. 1 hit.
[Graphical view ]
PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome structure and synthesis of infectious RNA from clones of tomato bushy stunt virus."
    Hearne P.Q., Knorr D.A., Hillman B.I., Morris T.J.
    Virology 177:141-151(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiRDRP_TBSVC
AccessioniPrimary (citable) accession number: P15962
Secondary accession number(s): Q88485
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: October 5, 2010
Last modified: April 16, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Readthrough of the terminator UAG occurs at position 297.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi