Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P15960 (P19_AMCV) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene names
ORF Names:ORF4
OrganismArtichoke mottled crinkle virus (AMCV)
Taxonomic identifier12142 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostCynara cardunculus var. scolymus (Artichoke) (Cynara scolymus) [TaxID: 59895]

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the tombusvirus protein p19 family.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionSuppressor of RNA silencing
Gene Ontology (GO)
   Cellular_componentvirion

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 172172RNA silencing suppressor p19
PRO_0000222871

Sequences

Sequence LengthMass (Da)Tools
P15960 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 5EE2911E6DA96901

FASTA17219,280
        10         20         30         40         50         60 
MERVIQGNDA REQANGERWD GGSGGTTSGF KLPDESPSWT EWRIHNDETD SNKDNPLGFK 

        70         80         90        100        110        120 
ESWGFGKVVF KRYLRYDRTE TSLHRVLGSW TGDSVNYAAS RFLGVNQIGC TYSIRFRGVS 

       130        140        150        160        170 
VTISGGSRTL QHICEMAIRS KQELLQLAPV EVESNVSRGR PEGAEAFKEE SE 

« Hide

References

[1]"Nucleotide sequence of the 3'-terminal region of artichoke mottled crinkle tombusvirus RNA."
Grieco F., Gallitelli D.
Nucleic Acids Res. 18:1300-1300(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
Strain: Bari-Dr. Gallitelli isolate.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X51456 Genomic RNA. Translation: CAA35823.1.
PIRNKVGBC. S08430.

3D structure databases

ProteinModelPortalP15960.
SMRP15960. Positions 9-152.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004905. Tombusvirus_p19.
[Graphical view]
PfamPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF103145. SSF103145. 1 hit.
ProtoNetSearch...

Entry information

Entry nameP19_AMCV
AccessionPrimary (citable) accession number: P15960
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 16, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families