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P15960

- P19_AMCV

UniProt

P15960 - P19_AMCV

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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Artichoke mottled crinkle virus (AMCV)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiArtichoke mottled crinkle virus (AMCV)
Taxonomic identifieri12142 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCynara cardunculus var. scolymus (Artichoke) (Cynara scolymus) [TaxID: 59895]

Subcellular locationi

GO - Cellular componenti

  1. virion Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172RNA silencing suppressor p19PRO_0000222871Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP15960.
SMRiP15960. Positions 9-152.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Family and domain databases

InterProiIPR004905. Tombusvirus_p19.
[Graphical view]
PfamiPF03220. Tombus_P19. 1 hit.
[Graphical view]
ProDomiPD005743. Tombus_P19. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF103145. SSF103145. 1 hit.

Sequencei

Sequence statusi: Complete.

P15960-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MERVIQGNDA REQANGERWD GGSGGTTSGF KLPDESPSWT EWRIHNDETD
60 70 80 90 100
SNKDNPLGFK ESWGFGKVVF KRYLRYDRTE TSLHRVLGSW TGDSVNYAAS
110 120 130 140 150
RFLGVNQIGC TYSIRFRGVS VTISGGSRTL QHICEMAIRS KQELLQLAPV
160 170
EVESNVSRGR PEGAEAFKEE SE
Length:172
Mass (Da):19,280
Last modified:April 1, 1990 - v1
Checksum:i5EE2911E6DA96901
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X51456 Genomic RNA. Translation: CAA35823.1.
PIRiS08430. NKVGBC.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X51456 Genomic RNA. Translation: CAA35823.1 .
PIRi S08430. NKVGBC.

3D structure databases

ProteinModelPortali P15960.
SMRi P15960. Positions 9-152.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004905. Tombusvirus_p19.
[Graphical view ]
Pfami PF03220. Tombus_P19. 1 hit.
[Graphical view ]
ProDomi PD005743. Tombus_P19. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF103145. SSF103145. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of the 3'-terminal region of artichoke mottled crinkle tombusvirus RNA."
    Grieco F., Gallitelli D.
    Nucleic Acids Res. 18:1300-1300(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    Strain: Bari-Dr. Gallitelli isolate.

Entry informationi

Entry nameiP19_AMCV
AccessioniPrimary (citable) accession number: P15960
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 1, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3