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P15953

- COX3_WHEAT

UniProt

P15953 - COX3_WHEAT

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Protein

Cytochrome c oxidase subunit 3

Gene

COX3

Organism
Triticum aestivum (Wheat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COX3
Encoded oniMitochondrion
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum

Organism-specific databases

GrameneiP15953.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Cytochrome c oxidase subunit 3PRO_0000183871Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP15953.
SMRiP15953. Positions 5-263.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei41 – 6121HelicalSequence AnalysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence AnalysisAdd
BLAST
Transmembranei137 – 15721HelicalSequence AnalysisAdd
BLAST
Transmembranei162 – 18221HelicalSequence AnalysisAdd
BLAST
Transmembranei200 – 22021HelicalSequence AnalysisAdd
BLAST
Transmembranei245 – 26521HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15953-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIESQRHSYH LVDPSPWPIS GSLGALATTV GGVMYMHSFQ GGATLLSLGL
60 70 80 90 100
IFILYTMFVW WRDVLRESTL EGHHTKAVQL GLRYGFILFI VSEVMFFFAF
110 120 130 140 150
FWAFFHSSLA PTVEIGGIWP PKGIGVLDPW EIPLLNTLIL LSSGAAVTWA
160 170 180 190 200
HHAILAGKEK RAVYALVATV LLALVFTGFQ GMEYYQAPFT ISDSIYGSTF
210 220 230 240 250
FLATGFHGFH VIIGTLFLIV CGIRQYLGQM TKKHHVGFEA AAWYWHFVDV
260
VWLFLFVSIY WWGGI
Length:265
Mass (Da):29,796
Last modified:August 1, 1992 - v2
Checksum:iA7918C9FBFC22608
GO

RNA editingi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X52539 mRNA. Translation: CAA36775.1.
X15944 Genomic DNA. Translation: CAA34071.1. Sequence problems.
PIRiS10331. OTWT3M.
RefSeqiYP_398397.1. NC_007579.1.

Genome annotation databases

GeneIDi3800086.

Keywords - Coding sequence diversityi

RNA editing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X52539 mRNA. Translation: CAA36775.1 .
X15944 Genomic DNA. Translation: CAA34071.1 . Sequence problems.
PIRi S10331. OTWT3M.
RefSeqi YP_398397.1. NC_007579.1.

3D structure databases

ProteinModelPortali P15953.
SMRi P15953. Positions 5-263.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3800086.

Organism-specific databases

Gramenei P15953.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure and transcription of the gene coding for subunit 3 of cytochrome oxidase in wheat mitochondria."
    Gualberto J.M., Domon C., Weil J.H., Grienenberger J.-M.
    Curr. Genet. 17:41-47(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Capitole.
  2. "Genetic code and phylogenetic origin of oomycetous mitochondria."
    Karlovsky P., Fartmann B.
    J. Mol. Evol. 34:254-258(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: cv. Capitole.
    Tissue: Etiolated plantlet.
  3. "Editing of the wheat coxIII transcript: evidence for twelve C to U and one U to C conversions and for sequence similarities around editing sites."
    Gualberto J.M., Weil J.H., Grienenberger J.M.
    Nucleic Acids Res. 18:3771-3776(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: RNA EDITING.

Entry informationi

Entry nameiCOX3_WHEAT
AccessioniPrimary (citable) accession number: P15953
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: August 1, 1992
Last modified: October 29, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3