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P15885 (BGLS_RUMAL) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
OrganismRuminococcus albus
Taxonomic identifier1264 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

Protein attributes

Sequence length947 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 947947Beta-glucosidase
PRO_0000210779

Sites

Active site6961 By similarity

Sequences

Sequence LengthMass (Da)Tools
P15885 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: C43B8CDD9D60A115

FASTA947104,278
        10         20         30         40         50         60 
MIKLDWNEYL EKAAEVNAEG AVLLVNNGVL PLDKNAVTQV FGRIQLDYYK SGTGSGGMVN 

        70         80         90        100        110        120 
VAKVTGITDG LIEAGAKLNE DVLKAYKDYV AEHPYDYGEG WGGEPWCQEE MPLDDSLVKR 

       130        140        150        160        170        180 
AAESSDTAIC IIGRTAGEEQ DNSCKAGSYL LTDGEKAILR KVRDNFSKMV ILLNVGNIID 

       190        200        210        220        230        240 
MGFIDEFSPD AVMYVWQGGM TGGTGTARVL LGEVSPCGKL PDTIAYDITD YPSDKNFHNR 

       250        260        270        280        290        300 
DVDIYAEDIF VGYRYFDTFA KDRVRFPFGY GLSYTQFEIS AEGRKTDDGV VITAKVKNIG 

       310        320        330        340        350        360 
SAAGKEVVQV YLEAPNCKLG KAARVLCGFE KTKVLAPNEE QTLTIEVTER DIASYDDSGI 

       370        380        390        400        410        420 
TGNAFAWVEE AGEYTFYAGS DVRSAKECFA FTLDSTKVIE QLEQALAPVT PFKRMVRTAE 

       430        440        450        460        470        480 
GLSYEDTPLS KVDEAARRLG YLPAETAYTG DKGIALSDVA HGKNTLDEFI AQLDDNDLNC 

       490        500        510        520        530        540 
LVRGEGMCSP KVTPGTAAAF GGVAKHLEEL GIPAGCCSDG PSGMRLDVGT KAFSLPNGTL 

       550        560        570        580        590        600 
IAATFNKSLI TELFTYLGLE MRANKVDCLL GPGMNIHRHP LNGRNFEYFS EDPFLTGTMA 

       610        620        630        640        650        660 
AAELEGLHSV GVEGTIKHFC ANNQETNRHF IDSVASERAL REIYLKGFEI AVRKSKARSV 

       670        680        690        700        710        720 
MTTYGKVNGL WTAGSFDLNT MILRKQWGFD GFTMTDWWAN INDRGCAPDK NNFAAMVRAQ 

       730        740        750        760        770        780 
NDVYMVCADG ESGSDNVIAA LADGRLTRAE LQRSARNILS FMMSTHAMAR KLGEDEAVEV 

       790        800        810        820        830        840 
INKPAETVDD GEGDRVFLLD GDLTIDMSGV KTERNLDYSF TVDVAQFGQY RMEMTASSTQ 

       850        860        870        880        890        900 
SELAQMPVTV FSMGTAWGTF TWNGTGGKPV TFAVEEMPMF SRYTIFRLHF GLGGLDMDKI 

       910        920        930        940 
VFKKIRPAEA QVCRLRISER WLQTQTYFWL KANFQSKKLL RGRRAYR 

« Hide

References

[1]"DNA sequence of a beta-glucosidase from Ruminococcus albus."
Ohmiya K., Takano M., Shimizu S.
Nucleic Acids Res. 18:671-671(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: F-40.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X15415 Genomic DNA. Translation: CAA33461.1.
PIRS08243.

3D structure databases

ProteinModelPortalP15885.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 2 hits.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLS_RUMAL
AccessionPrimary (citable) accession number: P15885
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 16, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries