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P15712 (PSTS1_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 102. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate-binding protein pstS 1
Short name=PBP 1
Short name=PstS-1
Alternative name(s):
Antigen Ag78
Protein antigen B
Short name=PAB
Gene names
Name:pstS1
Synonyms:phoS1
Ordered Locus Names:Rv0934, MT0961
ORF Names:MTCY08D9.05c
OrganismMycobacterium tuberculosis
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Part of the ABC transporter complex pstSACB involved in phosphate import By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (pstB), two transmembrane proteins (pstC and pstA) and a solute-binding protein (pstS) Probable.

Subcellular location

Cell membrane; Lipid-anchor Probable.

Sequence similarities

Belongs to the pstS family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 374351Phosphate-binding protein pstS 1
PRO_0000031854

Amino acid modifications

Lipidation241N-palmitoyl cysteine Potential
Lipidation241S-diacylglycerol cysteine Potential

Secondary structure

1 .................................................. 374
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P15712 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 6334968191FF38AA

FASTA37438,243
        10         20         30         40         50         60 
MKIRLHTLLA VLTAAPLLLA AAGCGSKPPS GSPETGAGAG TVATTPASSP VTLAETGSTL 

        70         80         90        100        110        120 
LYPLFNLWGP AFHERYPNVT ITAQGTGSGA GIAQAAAGTV NIGASDAYLS EGDMAAHKGL 

       130        140        150        160        170        180 
MNIALAISAQ QVNYNLPGVS EHLKLNGKVL AAMYQGTIKT WDDPQIAALN PGVNLPGTAV 

       190        200        210        220        230        240 
VPLHRSDGSG DTFLFTQYLS KQDPEGWGKS PGFGTTVDFP AVPGALGENG NGGMVTGCAE 

       250        260        270        280        290        300 
TPGCVAYIGI SFLDQASQRG LGEAQLGNSS GNFLLPDAQS IQAAAAGFAS KTPANQAISM 

       310        320        330        340        350        360 
IDGPAPDGYP IINYEYAIVN NRQKDAATAQ TLQAFLHWAI TDGNKASFLD QVHFQPLPPA 

       370 
VVKLSDALIA TISS

« Hide

References

« Hide 'large scale' references
[1]"Structure and mapping of antigenic domains of protein antigen b, a 38,000-molecular-weight protein of Mycobacterium tuberculosis."
Andersen A.B., Hansen E.B.
Infect. Immun. 57:2481-2488(1989) [PubMed: 2545626] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence."
Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. expand/collapse author list , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G.
Nature 393:537-544(1998) [PubMed: 9634230] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 25618 / H37Rv.
[3]"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains."
Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. expand/collapse author list , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.
J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CDC 1551 / Oshkosh.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M30046 Genomic DNA. Translation: AAA25374.1.
BX842575 Genomic DNA. Translation: CAE55339.1.
AE000516 Genomic DNA. Translation: AAK45208.1.
PIRF70584.
RefSeqNP_335394.1. NC_002755.2.
YP_177770.1. NC_000962.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1PC3X-ray2.16A/B25-374[»]
ProteinModelPortalP15712.
SMRP15712. Positions 42-374.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000000292; EBMYCP00000000292; EBMYCG00000000292.
EBMYCT00000070984; EBMYCP00000069043; EBMYCG00000070979.
GeneID885724.
926279.
GenomeReviewsGene locus MT0961 in contig AE000516_GR.
Gene locus Rv0934 in contig AL123456_GR.
KEGGmtc:MT0961.
mtu:Rv0934.
PATRIC18123856. VBIMycTub22151_1051.
TIGRMT0961.

Organism-specific databases

TubercuListRv0934.

Phylogenomic databases

GeneTreeEBGT00050000017160.
HOGENOMHBG428828.
OMATDPPVKE.
PhylomeDBP15712.
ProtClustDBCLSK799758.

Family and domain databases

InterProIPR005673. Peripla_phos-bd.
IPR006059. Solute-bd_1_bac.
[Graphical view]
KOK02040.
PfamPF01547. SBP_bac_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00975. 3a0107s03. 1 hit.
PROSITEPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSTS1_MYCTU
AccessionPrimary (citable) accession number: P15712
Secondary accession number(s): O05868
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: January 25, 2012
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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