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Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

NAD9

Organism
Paramecium tetraurelia
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Respiratory chain, Transport
LigandNAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
Protein P1
Gene namesi
Name:NAD9
Encoded oniMitochondrion
OrganismiParamecium tetraurelia
Taxonomic identifieri5888 [NCBI]
Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001186471 – 209NADH-ubiquinone oxidoreductase subunit 9Add BLAST209

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits.

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
PfamiView protein in Pfam
PF00329. Complex1_30kDa. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
PROSITEiView protein in PROSITE
PS00542. COMPLEX1_30K. 1 hit.

Sequencei

Sequence statusi: Complete.

P15600-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLNQIQRAC FCSGGVKKKK KPKYRFGFPM ALYFFFEKLN FSYWTSTTVN
60 70 80 90 100
PNHYVCVLPS EAGQALASVL GGELFLAKSQ LVEATAFDLT GQGAEAGDLL
110 120 130 140 150
VFLRNNGVVL SYSFYFFLLK KRITFFLHGG DKVSSLESFY SNANWLEREI
160 170 180 190 200
SEMFRGSNLL KKESRNLLLD YGSSFNPFLK KFPSTGHAEV VFNSFLKTTA

YVQTAGVEL
Length:209
Mass (Da):23,529
Last modified:April 1, 1990 - v1
Checksum:iD3D4477FDC0BFB43
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15917 Genomic DNA. Translation: CAA34058.1.
M15275 Genomic DNA. Translation: AAA79259.1.
PIRiS07725.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15917 Genomic DNA. Translation: CAA34058.1.
M15275 Genomic DNA. Translation: AAA79259.1.
PIRiS07725.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
PfamiView protein in Pfam
PF00329. Complex1_30kDa. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
PROSITEiView protein in PROSITE
PS00542. COMPLEX1_30K. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNDUS3_PARTE
AccessioniPrimary (citable) accession number: P15600
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: January 7, 2015
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.