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P15546

- COX3_STRPU

UniProt

P15546 - COX3_STRPU

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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Strongylocentrotus purpuratus (Purple sea urchin)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiStrongylocentrotus purpuratus (Purple sea urchin)
Taxonomic identifieri7668 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus
ProteomesiUP000007110: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 260260Cytochrome c oxidase subunit 3PRO_0000183858Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7668.P15546.

Structurei

3D structure databases

ProteinModelPortaliP15546.
SMRiP15546. Positions 5-260.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei41 – 6121HelicalSequence AnalysisAdd
BLAST
Transmembranei81 – 10121HelicalSequence AnalysisAdd
BLAST
Transmembranei133 – 15321HelicalSequence AnalysisAdd
BLAST
Transmembranei161 – 18121HelicalSequence AnalysisAdd
BLAST
Transmembranei196 – 21621HelicalSequence AnalysisAdd
BLAST
Transmembranei238 – 25821HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
InParanoidiP15546.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15546-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAIQHPYHLV DQSPWPLDGA FSGLMMTSGN VLWFHTQKTN LTLVGFLLLI
60 70 80 90 100
TNMVNWWRDI IRKANFQGSH TAIVNKGMRY GMILFITSEV CFFFAFFWAF
110 120 130 140 150
FHSSLAPSVE IGVAWPPSGI TPLNPFLVPL LNTGVLLSSG VTLSWSHHSI
160 170 180 190 200
LAGNRTESIQ ALFLTVALGS YFTALQAWEY IDAPFTIADS VYGSTFFVAT
210 220 230 240 250
GFHGLQVIIG TTFLMVCLFR TAGRHFSTHH HFGFEAAAWY WHFVDVVWFV
260
LYWLIYWWGA
Length:260
Mass (Da):29,489
Last modified:April 1, 1990 - v1
Checksum:i7416670412F81A00
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X12631 Genomic DNA. No translation available.
PIRiS01506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X12631 Genomic DNA. No translation available.
PIRi S01506.

3D structure databases

ProteinModelPortali P15546.
SMRi P15546. Positions 5-260.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7668.P15546.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG1845.
InParanoidi P15546.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence and gene organization of sea urchin mitochondrial DNA."
    Jacobs H.T., Elliott D.J., Math V.B., Farquharson A.
    J. Mol. Biol. 202:185-217(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiCOX3_STRPU
AccessioniPrimary (citable) accession number: P15546
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: October 29, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3