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P15546 (COX3_STRPU) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismStrongylocentrotus purpuratus (Purple sea urchin) [Reference proteome]
Taxonomic identifier7668 [NCBI]
Taxonomic lineageEukaryotaMetazoaEchinodermataEleutherozoaEchinozoaEchinoideaEuechinoideaEchinaceaEchinoidaStrongylocentrotidaeStrongylocentrotus

Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 260260Cytochrome c oxidase subunit 3
PRO_0000183858

Regions

Transmembrane41 – 6121Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane161 – 18121Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane238 – 25821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P15546 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 7416670412F81A00

FASTA26029,489
        10         20         30         40         50         60 
MAIQHPYHLV DQSPWPLDGA FSGLMMTSGN VLWFHTQKTN LTLVGFLLLI TNMVNWWRDI 

        70         80         90        100        110        120 
IRKANFQGSH TAIVNKGMRY GMILFITSEV CFFFAFFWAF FHSSLAPSVE IGVAWPPSGI 

       130        140        150        160        170        180 
TPLNPFLVPL LNTGVLLSSG VTLSWSHHSI LAGNRTESIQ ALFLTVALGS YFTALQAWEY 

       190        200        210        220        230        240 
IDAPFTIADS VYGSTFFVAT GFHGLQVIIG TTFLMVCLFR TAGRHFSTHH HFGFEAAAWY 

       250        260 
WHFVDVVWFV LYWLIYWWGA 

« Hide

References

[1]"Nucleotide sequence and gene organization of sea urchin mitochondrial DNA."
Jacobs H.T., Elliott D.J., Math V.B., Farquharson A.
J. Mol. Biol. 202:185-217(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X12631 Genomic DNA. No translation available.
PIRS01506.

3D structure databases

ProteinModelPortalP15546.
SMRP15546. Positions 5-260.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7668.P15546.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG1845.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_STRPU
AccessionPrimary (citable) accession number: P15546
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: April 16, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families