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Protein

Cytochrome c-552

Gene

HTH_0988

Organism
Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Reacts with hydrogenase.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei28Heme (covalent)1
Binding sitei31Heme (covalent)1
Metal bindingi32Iron (heme axial ligand)1
Metal bindingi77Iron (heme axial ligand)1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c-552
Alternative name(s):
Cytochrome c552
Gene namesi
Ordered Locus Names:HTH_0988, Hydth_0984
OrganismiHydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6)
Taxonomic identifieri608538 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeHydrogenobacter
Proteomesi
  • UP000002574 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 181 PublicationAdd BLAST18
ChainiPRO_000000653119 – 98Cytochrome c-5521 PublicationAdd BLAST80

Post-translational modificationi

Binds 1 heme group per subunit.

Interactioni

Protein-protein interaction databases

STRINGi608538.HTH_0988.

Structurei

Secondary structure

198
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi20 – 25Combined sources6
Helixi28 – 30Combined sources3
Beta strandi34 – 36Combined sources3
Beta strandi38 – 40Combined sources3
Helixi43 – 50Combined sources8
Helixi56 – 66Combined sources11
Beta strandi70 – 75Combined sources6
Helixi84 – 95Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AYGNMR-A19-98[»]
1YNRX-ray2.00A/B/C/D19-98[»]
2AI5NMR-A19-98[»]
3VYMX-ray2.00A19-98[»]
4ZIDX-ray1.80A19-98[»]
5AURX-ray1.26A/C/E/G19-98[»]
5AUSX-ray1.30A/C19-98[»]
ProteinModelPortaliP15452.
SMRiP15452.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP15452.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105W2Z. Bacteria.
COG4654. LUCA.
HOGENOMiHOG000254790.
KOiK08738.
OMAiATAKNCM.
OrthoDBiPOG091H0M5J.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002324. Cyt_c_ID.
[Graphical view]
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00606. CYTCHROMECID.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P15452-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKFLLVAVV GLAGITFANE QLAKQKGCMA CHDLKAKKVG PAYADVAKKY
60 70 80 90
AGRKDAVDYL AGKIKKGGSG VWGSVPMPPQ NVTDAEAKQL AQWILSIK
Length:98
Mass (Da):10,431
Last modified:August 1, 1992 - v2
Checksum:iF49713D829DDE927
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57735 Genomic DNA. Translation: CAA40902.1.
AP011112 Genomic DNA. Translation: BAI69446.1.
CP002221 Genomic DNA. Translation: ADO45379.1.
PIRiS32485.
RefSeqiWP_012963626.1. NC_017161.1.

Genome annotation databases

EnsemblBacteriaiADO45379; ADO45379; Hydth_0984.
BAI69446; BAI69446; HTH_0988.
KEGGihte:Hydth_0984.
hth:HTH_0988.
PATRICi32210897. VBIHydThe36152_0997.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57735 Genomic DNA. Translation: CAA40902.1.
AP011112 Genomic DNA. Translation: BAI69446.1.
CP002221 Genomic DNA. Translation: ADO45379.1.
PIRiS32485.
RefSeqiWP_012963626.1. NC_017161.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AYGNMR-A19-98[»]
1YNRX-ray2.00A/B/C/D19-98[»]
2AI5NMR-A19-98[»]
3VYMX-ray2.00A19-98[»]
4ZIDX-ray1.80A19-98[»]
5AURX-ray1.26A/C/E/G19-98[»]
5AUSX-ray1.30A/C19-98[»]
ProteinModelPortaliP15452.
SMRiP15452.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi608538.HTH_0988.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADO45379; ADO45379; Hydth_0984.
BAI69446; BAI69446; HTH_0988.
KEGGihte:Hydth_0984.
hth:HTH_0988.
PATRICi32210897. VBIHydThe36152_0997.

Phylogenomic databases

eggNOGiENOG4105W2Z. Bacteria.
COG4654. LUCA.
HOGENOMiHOG000254790.
KOiK08738.
OMAiATAKNCM.
OrthoDBiPOG091H0M5J.

Miscellaneous databases

EvolutionaryTraceiP15452.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002324. Cyt_c_ID.
[Graphical view]
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00606. CYTCHROMECID.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCY552_HYDTT
AccessioniPrimary (citable) accession number: P15452
Secondary accession number(s): D3DHZ4, E3EUH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: August 1, 1992
Last modified: November 2, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.