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P15447

- GLB4_GLYDI

UniProt

P15447 - GLB4_GLYDI

Protein

Globin, monomeric component M-IV

Gene
N/A
Organism
Glycera dibranchiata (Bloodworm)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi91 – 911Iron (heme axial ligand)

    GO - Molecular functioni

    1. heme binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. oxygen binding Source: InterPro
    4. oxygen transporter activity Source: UniProtKB-KW

    Keywords - Biological processi

    Oxygen transport, Transport

    Keywords - Ligandi

    Heme, Iron, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Globin, monomeric component M-IV
    Alternative name(s):
    GMH4
    OrganismiGlycera dibranchiata (Bloodworm)
    Taxonomic identifieri6350 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaGlyceridaeGlycera

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed2 Publications
    Chaini2 – 148147Globin, monomeric component M-IVPRO_0000052502Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.1 Publication

    Structurei

    Secondary structure

    1
    148
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi5 – 1915
    Turni20 – 245
    Helixi25 – 3814
    Helixi40 – 423
    Helixi43 – 464
    Beta strandi49 – 524
    Helixi55 – 7218
    Turni73 – 753
    Helixi77 – 9014
    Helixi91 – 933
    Beta strandi94 – 974
    Helixi101 – 1033
    Helixi104 – 11916
    Helixi120 – 1223
    Helixi125 – 14622

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1JF4X-ray1.40A2-148[»]
    1JL6X-ray1.40A2-148[»]
    1VRENMR-A2-148[»]
    1VRFNMR-A2-148[»]
    ProteinModelPortaliP15447.
    SMRiP15447. Positions 2-148.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP15447.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the globin family.PROSITE-ProRule annotation

    Family and domain databases

    Gene3Di1.10.490.10. 1 hit.
    InterProiIPR000971. Globin.
    IPR009050. Globin-like.
    IPR013316. Globin_annelid-type.
    IPR012292. Globin_dom.
    [Graphical view]
    PfamiPF00042. Globin. 1 hit.
    [Graphical view]
    PRINTSiPR01907. WORMGLOBIN.
    SUPFAMiSSF46458. SSF46458. 1 hit.
    PROSITEiPS01033. GLOBIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P15447-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGLSAAQRQV VASTWKDIAG SDNGAGVGKE CFTKFLSAHH DIAAVFGFSG    50
    ASDPGVADLG AKVLAQIGVA VSHLGDEGKM VAEMKAVGVR HKGYGYKHIK 100
    AEYFEPLGAS LLSAMEHRIG GKMTAAAKDA WAAAYADISG ALISGLQS 148
    Length:148
    Mass (Da):15,178
    Last modified:January 23, 2007 - v2
    Checksum:i9206F7FBE1CAB7F1
    GO

    Mass spectrometryi

    Molecular mass is 15031.6±3.8 Da from positions 2 - 148. Determined by ESI. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J02873 mRNA. Translation: AAA29162.1.
    PIRiA33420.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    J02873 mRNA. Translation: AAA29162.1 .
    PIRi A33420.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1JF4 X-ray 1.40 A 2-148 [» ]
    1JL6 X-ray 1.40 A 2-148 [» ]
    1VRE NMR - A 2-148 [» ]
    1VRF NMR - A 2-148 [» ]
    ProteinModelPortali P15447.
    SMRi P15447. Positions 2-148.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P15447.

    Family and domain databases

    Gene3Di 1.10.490.10. 1 hit.
    InterProi IPR000971. Globin.
    IPR009050. Globin-like.
    IPR013316. Globin_annelid-type.
    IPR012292. Globin_dom.
    [Graphical view ]
    Pfami PF00042. Globin. 1 hit.
    [Graphical view ]
    PRINTSi PR01907. WORMGLOBIN.
    SUPFAMi SSF46458. SSF46458. 1 hit.
    PROSITEi PS01033. GLOBIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "cDNA cloning and predicted amino acid sequence of Glycera dibranchiata monomer hemoglobin IV."
      Simons P.C., Satterlee J.D.
      Biochemistry 28:8525-8530(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-25.
    2. "Complete amino acid sequence of the Glycera dibranchiata monomer hemoglobin component IV: structural implications."
      Alam S.L., Satterlee J.D., Edmonds C.G.
      J. Protein Chem. 13:151-164(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 2-148, MASS SPECTROMETRY, 3D-STRUCTURE MODELING.
      Tissue: Erythrocyte.
    3. "Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO."
      Volkman B.F., Alam S.L., Satterlee J.D., Markley J.L.
      Biochemistry 37:10906-10919(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR.
    4. "Crystal structures of unligated and CN-ligated Glycera dibranchiata monomer ferric hemoglobin components III and IV."
      Park H.J., Yang C., Treff N., Satterlee J.D., Kang C.
      Proteins 49:49-60(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS)IN COMPLEX WITH HEME, SUBUNIT.

    Entry informationi

    Entry nameiGLB4_GLYDI
    AccessioniPrimary (citable) accession number: P15447
    Secondary accession number(s): P81779
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1990
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 86 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3