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P15447

- GLB4_GLYDI

UniProt

P15447 - GLB4_GLYDI

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Protein

Globin, monomeric component M-IV

Gene
N/A
Organism
Glycera dibranchiata (Bloodworm)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi91 – 911Iron (heme axial ligand)

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxygen binding Source: InterPro
  4. oxygen transporter activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Globin, monomeric component M-IV
Alternative name(s):
GMH4
OrganismiGlycera dibranchiata (Bloodworm)
Taxonomic identifieri6350 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataAciculataPhyllodocidaGlyceridaeGlycera

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed2 Publications
Chaini2 – 148147Globin, monomeric component M-IVPRO_0000052502Add
BLAST

Interactioni

Subunit structurei

Monomer.1 Publication

Structurei

Secondary structure

1
148
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi5 – 1915
Turni20 – 245
Helixi25 – 3814
Helixi40 – 423
Helixi43 – 464
Beta strandi49 – 524
Helixi55 – 7218
Turni73 – 753
Helixi77 – 9014
Helixi91 – 933
Beta strandi94 – 974
Helixi101 – 1033
Helixi104 – 11916
Helixi120 – 1223
Helixi125 – 14622

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1JF4X-ray1.40A2-148[»]
1JL6X-ray1.40A2-148[»]
1VRENMR-A2-148[»]
1VRFNMR-A2-148[»]
ProteinModelPortaliP15447.
SMRiP15447. Positions 2-148.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP15447.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR013316. Globin_annelid-type.
IPR012292. Globin_dom.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR01907. WORMGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P15447 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLSAAQRQV VASTWKDIAG SDNGAGVGKE CFTKFLSAHH DIAAVFGFSG
60 70 80 90 100
ASDPGVADLG AKVLAQIGVA VSHLGDEGKM VAEMKAVGVR HKGYGYKHIK
110 120 130 140
AEYFEPLGAS LLSAMEHRIG GKMTAAAKDA WAAAYADISG ALISGLQS
Length:148
Mass (Da):15,178
Last modified:January 23, 2007 - v2
Checksum:i9206F7FBE1CAB7F1
GO

Mass spectrometryi

Molecular mass is 15031.6±3.8 Da from positions 2 - 148. Determined by ESI. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J02873 mRNA. Translation: AAA29162.1.
PIRiA33420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
J02873 mRNA. Translation: AAA29162.1 .
PIRi A33420.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1JF4 X-ray 1.40 A 2-148 [» ]
1JL6 X-ray 1.40 A 2-148 [» ]
1VRE NMR - A 2-148 [» ]
1VRF NMR - A 2-148 [» ]
ProteinModelPortali P15447.
SMRi P15447. Positions 2-148.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P15447.

Family and domain databases

Gene3Di 1.10.490.10. 1 hit.
InterProi IPR000971. Globin.
IPR009050. Globin-like.
IPR013316. Globin_annelid-type.
IPR012292. Globin_dom.
[Graphical view ]
Pfami PF00042. Globin. 1 hit.
[Graphical view ]
PRINTSi PR01907. WORMGLOBIN.
SUPFAMi SSF46458. SSF46458. 1 hit.
PROSITEi PS01033. GLOBIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "cDNA cloning and predicted amino acid sequence of Glycera dibranchiata monomer hemoglobin IV."
    Simons P.C., Satterlee J.D.
    Biochemistry 28:8525-8530(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-25.
  2. "Complete amino acid sequence of the Glycera dibranchiata monomer hemoglobin component IV: structural implications."
    Alam S.L., Satterlee J.D., Edmonds C.G.
    J. Protein Chem. 13:151-164(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-148, MASS SPECTROMETRY, 3D-STRUCTURE MODELING.
    Tissue: Erythrocyte.
  3. "Solution structure and backbone dynamics of component IV Glycera dibranchiata monomeric hemoglobin-CO."
    Volkman B.F., Alam S.L., Satterlee J.D., Markley J.L.
    Biochemistry 37:10906-10919(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR.
  4. "Crystal structures of unligated and CN-ligated Glycera dibranchiata monomer ferric hemoglobin components III and IV."
    Park H.J., Yang C., Treff N., Satterlee J.D., Kang C.
    Proteins 49:49-60(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS)IN COMPLEX WITH HEME, SUBUNIT.

Entry informationi

Entry nameiGLB4_GLYDI
AccessioniPrimary (citable) accession number: P15447
Secondary accession number(s): P81779
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3