##gff-version 3
P15313	UniProtKB	Chain	1	513	.	.	.	ID=PRO_0000144624;Note=V-type proton ATPase subunit B%2C kidney isoform	
P15313	UniProtKB	Motif	510	513	.	.	.	Note=PDZ-binding;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12444018;Dbxref=PMID:12444018	
P15313	UniProtKB	Binding site	394	394	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P21281	
P15313	UniProtKB	Natural variant	30	30	.	.	.	ID=VAR_021011;Note=T->I;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12414817,ECO:0000269|Ref.3;Dbxref=dbSNP:rs17720303,PMID:12414817	
P15313	UniProtKB	Natural variant	31	513	.	.	.	ID=VAR_085740;Note=In DRTA2. Missing;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:19478356;Dbxref=dbSNP:rs121964879,PMID:19478356	
P15313	UniProtKB	Natural variant	81	81	.	.	.	ID=VAR_007866;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. L->P;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12414817,ECO:0000269|PubMed:12579397,ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=dbSNP:rs121964880,PMID:12414817,PMID:12579397,PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	123	123	.	.	.	ID=VAR_021012;Note=In DRTA2. G->V;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12414817;Dbxref=dbSNP:rs1343871627,PMID:12414817	
P15313	UniProtKB	Natural variant	124	124	.	.	.	ID=VAR_007867;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. R->W;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=dbSNP:rs727505222,PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	157	157	.	.	.	ID=VAR_021013;Note=In DRTA2. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12414817;Dbxref=dbSNP:rs782500780,PMID:12414817	
P15313	UniProtKB	Natural variant	161	161	.	.	.	ID=VAR_021014;Note=E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12414817;Dbxref=dbSNP:rs114234874,PMID:12414817	
P15313	UniProtKB	Natural variant	174	174	.	.	.	ID=VAR_007868;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. M->R;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	275	275	.	.	.	ID=VAR_007869;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. T->P;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12414817,ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=dbSNP:rs1161604514,PMID:12414817,PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	316	316	.	.	.	ID=VAR_007870;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. G->E;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=dbSNP:rs1553420413,PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	346	346	.	.	.	ID=VAR_007871;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. P->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12414817,ECO:0000269|PubMed:12579397,ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=dbSNP:rs781838938,PMID:12414817,PMID:12579397,PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	364	364	.	.	.	ID=VAR_007872;Note=In DRTA2%3B disruption of V-ATPase assembly resulting in loss of enzyme activity%3B impaired trafficking of V-ATPase to apical cell membrane%3B impaired renal proton secretion. G->S;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16769747,ECO:0000269|PubMed:9916796;Dbxref=PMID:16769747,PMID:9916796	
P15313	UniProtKB	Natural variant	465	465	.	.	.	ID=VAR_021015;Note=R->H;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:12579397,ECO:0000269|PubMed:27535533;Dbxref=dbSNP:rs142905621,PMID:12579397,PMID:27535533	
P15313	UniProtKB	Mutagenesis	513	513	.	.	.	Note=Loss of interactions with NHERF1 and SCL4A7. L->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12444018;Dbxref=PMID:12444018	
P15313	UniProtKB	Sequence conflict	467	467	.	.	.	Note=V->M;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P15313	UniProtKB	Sequence conflict	474	474	.	.	.	Note=G->S;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P15313	UniProtKB	Sequence conflict	503	503	.	.	.	Note=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305