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Protein

RNA silencing suppressor p19

Gene

ORF4

Organism
Cucumber necrosis virus (CNV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).By similarity

GO - Molecular functioni

Keywordsi

Molecular functionRNA-binding, Suppressor of RNA silencing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA silencing suppressor p19
Alternative name(s):
19 kDa symptom severity modulator
Gene namesi
ORF Names:ORF4
OrganismiCucumber necrosis virus (CNV)
Taxonomic identifieri12143 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCucumis sativus (Cucumber) [TaxID: 3659]
Proteomesi
  • UP000008565 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002228731 – 173RNA silencing suppressor p19Add BLAST173

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP15184
SMRiP15184
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tombusvirus protein p19 family.Curated

Phylogenomic databases

OrthoDBiVOG0900014I

Family and domain databases

Gene3Di2.60.40.18101 hit
InterProiView protein in InterPro
IPR004905 Tombusvirus_p19
IPR036131 VP19_sf
PfamiView protein in Pfam
PF03220 Tombus_P19, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005743 Tombus_P19, 1 hit
SUPFAMiSSF103145 SSF103145, 1 hit

Sequencei

Sequence statusi: Complete.

P15184-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAIQRSDA REQANSERWD GRCGGTITPF KLPDESPSLL EWRLHNSEES
60 70 80 90 100
EDKDHPLGFK ESWSFGKVVF KRYLRYDGTE TSLHRTLGSW ERNSVNDAAS
110 120 130 140 150
RFLGVSQIGC TYSIRFRGSC LTLSGGSRTL QRLIEMAIRT KRTMLQLTPC
160 170
EVEGNVSRRR PQGSEAFENK ESE
Length:173
Mass (Da):19,808
Last modified:April 1, 1990 - v1
Checksum:iD05F870D4AA4C80F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25270 Genomic RNA Translation: AAA42906.1
PIRiJA0133 NKVGCU
RefSeqiNP_040957.1, NC_001469.1

Genome annotation databases

GeneIDi1493948
KEGGivg:1493948

Similar proteinsi

Entry informationi

Entry nameiP19_CNV
AccessioniPrimary (citable) accession number: P15184
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome