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P15183

- CAPSD_CNV

UniProt

P15183 - CAPSD_CNV

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Protein

Capsid protein

Gene
ORF2
Organism
Cucumber necrosis virus (CNV)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.1 Publication

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. structural molecule activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
p41
Gene namesi
ORF Names:ORF2
OrganismiCucumber necrosis virus (CNV)
Taxonomic identifieri12143 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCucumis sativus (Cucumber) [TaxID: 3659]
ProteomesiUP000008565: Genome

Subcellular locationi

Virion Reviewed prediction

GO - Cellular componenti

  1. T=3 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Capsid proteinPRO_0000222861Add
BLAST

Interactioni

Subunit structurei

Homomultimer Reviewed prediction.

Structurei

Secondary structure

1
380
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi94 – 10714
Helixi115 – 1173
Turni131 – 1333
Turni135 – 1373
Helixi138 – 1414
Beta strandi144 – 15815
Beta strandi167 – 1759
Turni184 – 1863
Helixi187 – 1893
Beta strandi191 – 1966
Beta strandi202 – 2054
Turni218 – 2203
Helixi223 – 2264
Beta strandi230 – 2378
Beta strandi241 – 25717
Beta strandi264 – 2696
Beta strandi271 – 2744
Beta strandi276 – 2805
Beta strandi284 – 2896
Beta strandi294 – 2985
Beta strandi302 – 3109
Beta strandi319 – 3246
Beta strandi327 – 3348
Beta strandi339 – 3479
Beta strandi352 – 3554
Beta strandi364 – 3707

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
ProteinModelPortaliP15183.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 9292R domain, interaction with RNAAdd
BLAST
Regioni48 – 536Involved in encapsidation Inferred
Regioni93 – 254162S domain, virion shellAdd
BLAST
Regioni255 – 380126P domain, projectingAdd
BLAST

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15183-1 [UniParc]FASTAAdd to Basket

« Hide

MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK    50
KGKNGNGALI AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE 100
YVSVLSGTNG EFLRNNGTGP NNDFSINPLN PFLFPWLVNI AANFDQYKFN 150
SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG PDDRAALANY AHLSEISPWA 200
ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT AELGDIFVEY 250
TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV 300
PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN 350
ANLSLSGLTG ATNAQLFAVR AITENAVQVV 380
Length:380
Mass (Da):40,878
Last modified:April 1, 1990 - v1
Checksum:i793CB6B05CEC6669
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1.
PIRiJA0131. VCVGCN.
RefSeqiNP_040955.1. NC_001469.1.

Genome annotation databases

GeneIDi1493950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1 .
PIRi JA0131. VCVGCN.
RefSeqi NP_040955.1. NC_001469.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4LLF X-ray 2.89 A/B/D/E/F/G/H/I/J/K/L/M/N/O/P 1-380 [» ]
ProteinModelPortali P15183.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1493950.

Family and domain databases

Gene3Di 2.60.120.20. 1 hit.
InterProi IPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view ]
Pfami PF00729. Viral_coat. 1 hit.
[Graphical view ]
PRINTSi PR00233. ICOSAHEDRAL.
PROSITEi PS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete nucleotide sequence of the cucumber necrosis virus genome."
    Rochon D.M., Tremaine J.H.
    Virology 169:251-259(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "A highly basic KGKKGK sequence in the RNA-binding domain of the Cucumber necrosis virus coat protein is associated with encapsidation of full-length CNV RNA during infection."
    Reade R., Kakani K., Rochon D.
    Virology 403:181-188(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: RNA-BINDING, FUNCTION.

Entry informationi

Entry nameiCAPSD_CNV
AccessioniPrimary (citable) accession number: P15183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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