Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P15183

- CAPSD_CNV

UniProt

P15183 - CAPSD_CNV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Capsid protein

Gene

ORF2

Organism
Cucumber necrosis virus (CNV)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.1 Publication

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. structural molecule activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
p41
Gene namesi
ORF Names:ORF2
OrganismiCucumber necrosis virus (CNV)
Taxonomic identifieri12143 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCucumis sativus (Cucumber) [TaxID: 3659]
ProteomesiUP000008565: Genome

Subcellular locationi

Virion Curated

GO - Cellular componenti

  1. T=3 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Capsid proteinPRO_0000222861Add
BLAST

Interactioni

Subunit structurei

Homomultimer.Curated

Structurei

Secondary structure

1
380
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi94 – 10714Combined sources
Helixi115 – 1173Combined sources
Turni131 – 1333Combined sources
Turni135 – 1373Combined sources
Helixi138 – 1414Combined sources
Beta strandi144 – 15815Combined sources
Beta strandi167 – 1759Combined sources
Turni184 – 1863Combined sources
Helixi187 – 1893Combined sources
Beta strandi191 – 1966Combined sources
Beta strandi202 – 2054Combined sources
Turni218 – 2203Combined sources
Helixi223 – 2264Combined sources
Beta strandi230 – 2378Combined sources
Beta strandi241 – 25717Combined sources
Beta strandi264 – 2696Combined sources
Beta strandi271 – 2744Combined sources
Beta strandi276 – 2805Combined sources
Beta strandi284 – 2896Combined sources
Beta strandi294 – 2985Combined sources
Beta strandi302 – 3109Combined sources
Beta strandi319 – 3246Combined sources
Beta strandi327 – 3348Combined sources
Beta strandi339 – 3479Combined sources
Beta strandi352 – 3554Combined sources
Beta strandi364 – 3707Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
ProteinModelPortaliP15183.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 9292R domain, interaction with RNAAdd
BLAST
Regioni48 – 536Involved in encapsidationCurated
Regioni93 – 254162S domain, virion shellAdd
BLAST
Regioni255 – 380126P domain, projectingAdd
BLAST

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15183-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK
60 70 80 90 100
KGKNGNGALI AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE
110 120 130 140 150
YVSVLSGTNG EFLRNNGTGP NNDFSINPLN PFLFPWLVNI AANFDQYKFN
160 170 180 190 200
SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG PDDRAALANY AHLSEISPWA
210 220 230 240 250
ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT AELGDIFVEY
260 270 280 290 300
TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV
310 320 330 340 350
PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN
360 370 380
ANLSLSGLTG ATNAQLFAVR AITENAVQVV
Length:380
Mass (Da):40,878
Last modified:April 1, 1990 - v1
Checksum:i793CB6B05CEC6669
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1.
PIRiJA0131. VCVGCN.
RefSeqiNP_040955.1. NC_001469.1.

Genome annotation databases

GeneIDi1493950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1 .
PIRi JA0131. VCVGCN.
RefSeqi NP_040955.1. NC_001469.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4LLF X-ray 2.89 A/B/D/E/F/G/H/I/J/K/L/M/N/O/P 1-380 [» ]
ProteinModelPortali P15183.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1493950.

Family and domain databases

Gene3Di 2.60.120.20. 1 hit.
InterProi IPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view ]
Pfami PF00729. Viral_coat. 1 hit.
[Graphical view ]
PRINTSi PR00233. ICOSAHEDRAL.
PROSITEi PS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete nucleotide sequence of the cucumber necrosis virus genome."
    Rochon D.M., Tremaine J.H.
    Virology 169:251-259(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
  2. "A highly basic KGKKGK sequence in the RNA-binding domain of the Cucumber necrosis virus coat protein is associated with encapsidation of full-length CNV RNA during infection."
    Reade R., Kakani K., Rochon D.
    Virology 403:181-188(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: RNA-BINDING, FUNCTION.

Entry informationi

Entry nameiCAPSD_CNV
AccessioniPrimary (citable) accession number: P15183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: November 26, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3