P15183 (CAPSD_CNV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid protein

Alternative name(s):
Coat protein
p41

Gene names

ORF Names:

ORF2

Organism

Cucumber necrosis virus (CNV) [Complete proteome]

Taxonomic identifier

12143 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Tombusviridae › Tombusvirus

Virus host

Cucumis sativus (Cucumber) [TaxID: 3659]

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Ref.2
Subunit structure	Homomultimer Potential.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the icosahedral plant coat protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding
Molecular function	Capsid protein T=3 icosahedral capsid protein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	T=3 icosahedral viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 380	380	Capsid protein		PRO_0000222861
Regions
	Region	1 – 92	92	R domain, interaction with RNA
	Region	48 – 53	6	Involved in encapsidation Probable
	Region	93 – 254	162	S domain, virion shell
	Region	255 – 380	126	P domain, projecting

Sequences

	Sequence		Length	Mass (Da)
	P15183 [UniParc]. Last modified April 1, 1990. Version 1. Checksum: 793CB6B05CEC6669	FASTA	380	40,878
	10 20 30 40 50 60 MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK KGKNGNGALI 70 80 90 100 110 120 AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE YVSVLSGTNG EFLRNNGTGP 130 140 150 160 170 180 NNDFSINPLN PFLFPWLVNI AANFDQYKFN SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG 190 200 210 220 230 240 PDDRAALANY AHLSEISPWA ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT 250 260 270 280 290 300 AELGDIFVEY TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV 310 320 330 340 350 360 PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN ANLSLSGLTG 370 380 ATNAQLFAVR AITENAVQVV

References

[1]	"Complete nucleotide sequence of the cucumber necrosis virus genome." Rochon D.M., Tremaine J.H. Virology 169:251-259(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"A highly basic KGKKGK sequence in the RNA-binding domain of the Cucumber necrosis virus coat protein is associated with encapsidation of full-length CNV RNA during infection." Reade R., Kakani K., Rochon D. Virology 403:181-188(2010) [PubMed] [Europe PMC] [Abstract] Cited for: RNA-BINDING, FUNCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M25270 Genomic RNA. Translation: AAA42904.1.
PIR	VCVGCN. JA0131.
RefSeq	NP_040955.1. NC_001469.1.
3D structure databases
ProteinModelPortal	P15183.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1493950.
Family and domain databases
InterPro	IPR000937. Capsid_prot_S-dom_vir. [Graphical view]
Pfam	PF00729. Viral_coat. 1 hit. [Graphical view]
PRINTS	PR00233. ICOSAHEDRAL.
PROSITE	PS00555. ICOSAH_VIR_COAT_S. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPSD_CNV

Accession

Primary (citable) accession number: P15183

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program