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Protein

Capsid protein

Gene

ORF2

Organism
Cucumber necrosis virus (CNV)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
p41
Gene namesi
ORF Names:ORF2
OrganismiCucumber necrosis virus (CNV)
Taxonomic identifieri12143 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCucumis sativus (Cucumber) [TaxID: 3659]
Proteomesi
  • UP000008565 Componenti: Genome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002228611 – 380Capsid proteinAdd BLAST380

Interactioni

Subunit structurei

Homomultimer.Curated

Structurei

Secondary structure

1380
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi86 – 89Combined sources4
Beta strandi94 – 107Combined sources14
Helixi115 – 117Combined sources3
Turni131 – 133Combined sources3
Turni135 – 137Combined sources3
Helixi138 – 141Combined sources4
Beta strandi144 – 158Combined sources15
Beta strandi167 – 175Combined sources9
Turni184 – 186Combined sources3
Helixi187 – 189Combined sources3
Beta strandi191 – 196Combined sources6
Beta strandi202 – 205Combined sources4
Turni218 – 220Combined sources3
Helixi223 – 226Combined sources4
Beta strandi230 – 237Combined sources8
Beta strandi241 – 257Combined sources17
Beta strandi264 – 269Combined sources6
Beta strandi271 – 274Combined sources4
Beta strandi276 – 280Combined sources5
Beta strandi284 – 289Combined sources6
Beta strandi294 – 298Combined sources5
Beta strandi302 – 310Combined sources9
Beta strandi319 – 324Combined sources6
Beta strandi327 – 334Combined sources8
Beta strandi339 – 347Combined sources9
Beta strandi352 – 355Combined sources4
Beta strandi364 – 370Combined sources7

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
ProteinModelPortaliP15183.
SMRiP15183.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 92R domain, interaction with RNAAdd BLAST92
Regioni48 – 53Involved in encapsidationCurated6
Regioni93 – 254S domain, virion shellAdd BLAST162
Regioni255 – 380P domain, projectingAdd BLAST126

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15183-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK
60 70 80 90 100
KGKNGNGALI AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE
110 120 130 140 150
YVSVLSGTNG EFLRNNGTGP NNDFSINPLN PFLFPWLVNI AANFDQYKFN
160 170 180 190 200
SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG PDDRAALANY AHLSEISPWA
210 220 230 240 250
ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT AELGDIFVEY
260 270 280 290 300
TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV
310 320 330 340 350
PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN
360 370 380
ANLSLSGLTG ATNAQLFAVR AITENAVQVV
Length:380
Mass (Da):40,878
Last modified:April 1, 1990 - v1
Checksum:i793CB6B05CEC6669
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1.
PIRiJA0131. VCVGCN.
RefSeqiNP_040955.1. NC_001469.1.

Genome annotation databases

GeneIDi1493950.
KEGGivg:1493950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M25270 Genomic RNA. Translation: AAA42904.1.
PIRiJA0131. VCVGCN.
RefSeqiNP_040955.1. NC_001469.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
ProteinModelPortaliP15183.
SMRiP15183.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1493950.
KEGGivg:1493950.

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCAPSD_CNV
AccessioniPrimary (citable) accession number: P15183
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.