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P15183

- CAPSD_CNV

UniProt

P15183 - CAPSD_CNV

Protein

Capsid protein

Gene

ORF2

Organism
Cucumber necrosis virus (CNV)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (01 Apr 1990)
      Previous versions | rss
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    Functioni

    Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.1 Publication

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW
    2. structural molecule activity Source: InterPro

    Keywords - Ligandi

    RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Capsid protein
    Alternative name(s):
    Coat protein
    p41
    Gene namesi
    ORF Names:ORF2
    OrganismiCucumber necrosis virus (CNV)
    Taxonomic identifieri12143 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
    Virus hostiCucumis sativus (Cucumber) [TaxID: 3659]
    ProteomesiUP000008565: Genome

    Subcellular locationi

    Virion Curated

    GO - Cellular componenti

    1. T=3 icosahedral viral capsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, T=3 icosahedral capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 380380Capsid proteinPRO_0000222861Add
    BLAST

    Interactioni

    Subunit structurei

    Homomultimer.Curated

    Structurei

    Secondary structure

    1
    380
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi94 – 10714
    Helixi115 – 1173
    Turni131 – 1333
    Turni135 – 1373
    Helixi138 – 1414
    Beta strandi144 – 15815
    Beta strandi167 – 1759
    Turni184 – 1863
    Helixi187 – 1893
    Beta strandi191 – 1966
    Beta strandi202 – 2054
    Turni218 – 2203
    Helixi223 – 2264
    Beta strandi230 – 2378
    Beta strandi241 – 25717
    Beta strandi264 – 2696
    Beta strandi271 – 2744
    Beta strandi276 – 2805
    Beta strandi284 – 2896
    Beta strandi294 – 2985
    Beta strandi302 – 3109
    Beta strandi319 – 3246
    Beta strandi327 – 3348
    Beta strandi339 – 3479
    Beta strandi352 – 3554
    Beta strandi364 – 3707

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
    ProteinModelPortaliP15183.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni1 – 9292R domain, interaction with RNAAdd
    BLAST
    Regioni48 – 536Involved in encapsidationCurated
    Regioni93 – 254162S domain, virion shellAdd
    BLAST
    Regioni255 – 380126P domain, projectingAdd
    BLAST

    Sequence similaritiesi

    Family and domain databases

    Gene3Di2.60.120.20. 1 hit.
    InterProiIPR000937. Capsid_prot_S-dom_vir.
    IPR029053. Viral_coat.
    [Graphical view]
    PfamiPF00729. Viral_coat. 1 hit.
    [Graphical view]
    PRINTSiPR00233. ICOSAHEDRAL.
    PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P15183-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK    50
    KGKNGNGALI AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE 100
    YVSVLSGTNG EFLRNNGTGP NNDFSINPLN PFLFPWLVNI AANFDQYKFN 150
    SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG PDDRAALANY AHLSEISPWA 200
    ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT AELGDIFVEY 250
    TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV 300
    PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN 350
    ANLSLSGLTG ATNAQLFAVR AITENAVQVV 380
    Length:380
    Mass (Da):40,878
    Last modified:April 1, 1990 - v1
    Checksum:i793CB6B05CEC6669
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25270 Genomic RNA. Translation: AAA42904.1.
    PIRiJA0131. VCVGCN.
    RefSeqiNP_040955.1. NC_001469.1.

    Genome annotation databases

    GeneIDi1493950.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M25270 Genomic RNA. Translation: AAA42904.1 .
    PIRi JA0131. VCVGCN.
    RefSeqi NP_040955.1. NC_001469.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4LLF X-ray 2.89 A/B/D/E/F/G/H/I/J/K/L/M/N/O/P 1-380 [» ]
    ProteinModelPortali P15183.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1493950.

    Family and domain databases

    Gene3Di 2.60.120.20. 1 hit.
    InterProi IPR000937. Capsid_prot_S-dom_vir.
    IPR029053. Viral_coat.
    [Graphical view ]
    Pfami PF00729. Viral_coat. 1 hit.
    [Graphical view ]
    PRINTSi PR00233. ICOSAHEDRAL.
    PROSITEi PS00555. ICOSAH_VIR_COAT_S. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete nucleotide sequence of the cucumber necrosis virus genome."
      Rochon D.M., Tremaine J.H.
      Virology 169:251-259(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
    2. "A highly basic KGKKGK sequence in the RNA-binding domain of the Cucumber necrosis virus coat protein is associated with encapsidation of full-length CNV RNA during infection."
      Reade R., Kakani K., Rochon D.
      Virology 403:181-188(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: RNA-BINDING, FUNCTION.

    Entry informationi

    Entry nameiCAPSD_CNV
    AccessioniPrimary (citable) accession number: P15183
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1990
    Last sequence update: April 1, 1990
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3