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P15183 (CAPSD_CNV) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Capsid protein
Alternative name(s):
Coat protein
p41
Gene names
ORF Names:ORF2
OrganismCucumber necrosis virus (CNV) [Complete proteome]
Taxonomic identifier12143 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostCucumis sativus (Cucumber) [TaxID: 3659]

Protein attributes

Sequence length380 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Ref.2

Subunit structure

Homomultimer Potential.

Subcellular location

Virion Potential.

Sequence similarities

Belongs to the icosahedral plant coat protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
T=3 icosahedral capsid protein
Virion
   LigandRNA-binding
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Cellular_componentT=3 icosahedral viral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural molecule activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 380380Capsid protein
PRO_0000222861

Regions

Region1 – 9292R domain, interaction with RNA
Region48 – 536Involved in encapsidation Probable
Region93 – 254162S domain, virion shell
Region255 – 380126P domain, projecting

Secondary structure

................................................... 380
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P15183 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 793CB6B05CEC6669

FASTA38040,878
        10         20         30         40         50         60 
MALVSRNNNM RTLAKLAAPL ATAGTRTIVD NKEAIWNGVK WIWGKLPKGK KGKNGNGALI 

        70         80         90        100        110        120 
AHPQAFPGAI AAPISYAYAV KGRKPRFQTA KGSVRITHRE YVSVLSGTNG EFLRNNGTGP 

       130        140        150        160        170        180 
NNDFSINPLN PFLFPWLVNI AANFDQYKFN SLRFEYVPLV NTTTNGRVAL YFDKDSEDPG 

       190        200        210        220        230        240 
PDDRAALANY AHLSEISPWA ITKLTVPTDN VKRFISDTSS GDPKLINLGQ FGWVAYSGPT 

       250        260        270        280        290        300 
AELGDIFVEY TVDLFEAQPT SPLLESLFRE SASSVQTRMG LPYFSLEVAS ATDLVWQARV 

       310        320        330        340        350        360 
PGTYVVTIIF NSTVGGLTPS ISGGGTINSS FSVSTAGSSA YVANITIRVN ANLSLSGLTG 

       370        380 
ATNAQLFAVR AITENAVQVV 

« Hide

References

[1]"Complete nucleotide sequence of the cucumber necrosis virus genome."
Rochon D.M., Tremaine J.H.
Virology 169:251-259(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"A highly basic KGKKGK sequence in the RNA-binding domain of the Cucumber necrosis virus coat protein is associated with encapsidation of full-length CNV RNA during infection."
Reade R., Kakani K., Rochon D.
Virology 403:181-188(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: RNA-BINDING, FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M25270 Genomic RNA. Translation: AAA42904.1.
PIRVCVGCN. JA0131.
RefSeqNP_040955.1. NC_001469.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4LLFX-ray2.89A/B/D/E/F/G/H/I/J/K/L/M/N/O/P1-380[»]
ProteinModelPortalP15183.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1493950.

Family and domain databases

Gene3D2.60.120.20. 1 hit.
InterProIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSPR00233. ICOSAHEDRAL.
PROSITEPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPSD_CNV
AccessionPrimary (citable) accession number: P15183
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references