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Protein

Glucitol operon activator protein

Gene

gutM

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Positive regulator for glucitol operon expression.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi23 – 297H-T-H motifSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Phosphotransferase system, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:PD00345.
ECOL316407:JW2675-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucitol operon activator protein
Gene namesi
Name:gutM
Synonyms:srlM
Ordered Locus Names:b2706, JW2675
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10972. gutM.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 119119Glucitol operon activator proteinPRO_0000083878Add
BLAST

Proteomic databases

PaxDbiP15081.

Interactioni

Protein-protein interaction databases

BioGridi4262002. 20 interactions.
STRINGi511145.b2706.

Structurei

3D structure databases

ProteinModelPortaliP15081.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105J92. Bacteria.
COG4578. LUCA.
HOGENOMiHOG000124047.
KOiK02466.
OMAiQIALGWW.
OrthoDBiEOG61KBKR.

Family and domain databases

InterProiIPR009693. Glucitol_operon_activator.
[Graphical view]
PfamiPF06923. GutM. 1 hit.
[Graphical view]
PIRSFiPIRSF011474. Glucitol_operon_activator. 1 hit.

Sequencei

Sequence statusi: Complete.

P15081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSALITVAV IAWCAQLALG GWQISRFNRA FDTLCQQGRV GVGRSSGRFK
60 70 80 90 100
PRVVVAIALD DQQRIVDTLF MKGLTVFARP QKIPAITGMH AGDLQPDVIF
110
PHDPLSQNAL SLALKLKRG
Length:119
Mass (Da):12,953
Last modified:April 1, 1990 - v1
Checksum:i6AE795316A5A221C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02708 Genomic DNA. Translation: AAC13414.1.
X13463 Genomic DNA. Translation: CAA31819.1.
U29579 Genomic DNA. Translation: AAA69215.1.
U00096 Genomic DNA. Translation: AAC75748.1.
AP009048 Genomic DNA. Translation: BAA16567.1.
PIRiS01831.
RefSeqiNP_417186.1. NC_000913.3.
WP_000252908.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75748; AAC75748; b2706.
BAA16567; BAA16567; BAA16567.
GeneIDi948938.
KEGGiecj:JW2675.
eco:b2706.
PATRICi32120810. VBIEscCol129921_2797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J02708 Genomic DNA. Translation: AAC13414.1.
X13463 Genomic DNA. Translation: CAA31819.1.
U29579 Genomic DNA. Translation: AAA69215.1.
U00096 Genomic DNA. Translation: AAC75748.1.
AP009048 Genomic DNA. Translation: BAA16567.1.
PIRiS01831.
RefSeqiNP_417186.1. NC_000913.3.
WP_000252908.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP15081.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262002. 20 interactions.
STRINGi511145.b2706.

Proteomic databases

PaxDbiP15081.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75748; AAC75748; b2706.
BAA16567; BAA16567; BAA16567.
GeneIDi948938.
KEGGiecj:JW2675.
eco:b2706.
PATRICi32120810. VBIEscCol129921_2797.

Organism-specific databases

EchoBASEiEB0965.
EcoGeneiEG10972. gutM.

Phylogenomic databases

eggNOGiENOG4105J92. Bacteria.
COG4578. LUCA.
HOGENOMiHOG000124047.
KOiK02466.
OMAiQIALGWW.
OrthoDBiEOG61KBKR.

Enzyme and pathway databases

BioCyciEcoCyc:PD00345.
ECOL316407:JW2675-MONOMER.

Miscellaneous databases

PROiP15081.

Family and domain databases

InterProiIPR009693. Glucitol_operon_activator.
[Graphical view]
PfamiPF06923. GutM. 1 hit.
[Graphical view]
PIRSFiPIRSF011474. Glucitol_operon_activator. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Positive and negative regulators for glucitol (gut) operon expression in Escherichia coli."
    Yamada M., Saier M.H. Jr.
    J. Mol. Biol. 203:569-583(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features."
    Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T.
    , Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.
    DNA Res. 4:91-113(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiGUTM_ECOLI
AccessioniPrimary (citable) accession number: P15081
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: January 20, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.