P15031 (FECE_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fe(3+) dicitrate transport ATP-binding protein FecE

Alternative name(s):
Iron(III) dicitrate transport ATP-binding protein FecE

Gene names

Name:	fecE
Ordered Locus Names:	b4287, JW4247

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the binding-protein-dependent transport system for citrate-dependent Fe3+. Probably responsible for energy coupling to the transport system.
Subcellular location	Cell inner membrane; Peripheral membrane protein.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Ion transport Iron transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Iron Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ion transport Inferred from electronic annotation. Source: UniProtKB-KW iron ion homeostasis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Fe(3+) dicitrate transport ATP-binding protein FecE		PRO_0000092324
Regions
	Domain	3 – 238	236	ABC transporter
	Nucleotide binding	35 – 42	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P15031 [UniParc]. Last modified April 1, 1990. Version 1. Checksum: 89785C2A91D51FF3	FASTA	255	28,191
	10 20 30 40 50 60 MTLRTENLTV SYGTDKVLND VSLSLPTGKI TALIGPNGCG KSTLLNCFSR LLMPQSGTVF 70 80 90 100 110 120 LGDNPINMLS SRQLARRLSL LPQHHLTPEG ITVQELVSYG RNPWLSLWGR LSAEDNARVN 130 140 150 160 170 180 VAMNQTRINH LAVRRLTELS GGQRQRAFLA MVLAQNTPVV LLDEPTTYLD INHQVDLMRL 190 200 210 220 230 240 MGELRTQGKT VVAVLHDLNQ ASRYCDQLVV MANGHVMAQG TPEEVMTPGL LRTVFSVEAE 250 IHPEPVSGRP MCLMR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli." Staudenmaier H., van Hove B., Yaraghi Z., Braun V. J. Bacteriol. 171:2626-2633(1989) [PubMed: 2651410] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes." Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R. Nucleic Acids Res. 23:2105-2119(1995) [PubMed: 7610040] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M26397 Genomic DNA. Translation: AAA23765.1. U14003 Genomic DNA. Translation: AAA97183.1. U00096 Genomic DNA. Translation: AAC77243.1. AP009048 Genomic DNA. Translation: BAE78278.1.
PIR	QRECM3. JS0115.
RefSeq	NP_418707.1. NC_000913.2.
3D structure databases
ProteinModelPortal	P15031.
SMR	P15031. Positions 1-253.
ModBase	Search...
Protein-protein interaction databases
IntAct	P15031. 2 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000004485; EBESCP00000004485; EBESCG00000003661. EBESCT00000016916; EBESCP00000016207; EBESCG00000015975.
GeneID	948819.
GenomeReviews	Gene locus JW4247 in contig AP009048_GR. Gene locus b4287 in contig U00096_GR.
KEGG	ecj:JW4247. eco:b4287.
PATRIC	32124151. VBIEscCol129921_4419.
Organism-specific databases
EchoBASE	EB0286.
EcoGene	EG10290. fecE.
Phylogenomic databases
eggNOG	COG1120.
GeneTree	EBGT00050000008237.
HOGENOM	HBG758042.
OMA	VELMALM.
PhylomeDB	P15031.
ProtClustDB	PRK11231.
Enzyme and pathway databases
BioCyc	EcoCyc:FECE-MONOMER.
Gene expression databases
Genevestigator	P15031.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K02013.
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FECE_ECOLI

Accession

Primary (citable) accession number: P15031
Secondary accession number(s): Q2M628

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	January 25, 2012
This is version 99 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program