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Protein

Fe(3+) dicitrate transport ATP-binding protein FecE

Gene

fecE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the binding-protein-dependent transport system for citrate-dependent Fe3+. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 42ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity Source: InterPro
  • ATP binding Source: EcoCyc

GO - Biological processi

Keywordsi

Biological processIon transport, Iron transport, Transport
LigandATP-binding, Iron, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:FECE-MONOMER
MetaCyc:FECE-MONOMER

Protein family/group databases

TCDBi3.A.1.14.1 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Fe(3+) dicitrate transport ATP-binding protein FecE
Alternative name(s):
Iron(III) dicitrate transport ATP-binding protein FecE
Gene namesi
Name:fecE
Ordered Locus Names:b4287, JW4247
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10290 fecE

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000923241 – 255Fe(3+) dicitrate transport ATP-binding protein FecEAdd BLAST255

Proteomic databases

PaxDbiP15031
PRIDEiP15031

Expressioni

Inductioni

Induced 1.6-fold by hydroxyurea.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262739, 249 interactors
IntActiP15031, 2 interactors
STRINGi316385.ECDH10B_4485

Structurei

3D structure databases

ProteinModelPortaliP15031
SMRiP15031
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 238ABC transporterPROSITE-ProRule annotationAdd BLAST236

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Phylogenomic databases

eggNOGiENOG4105E0A Bacteria
COG1120 LUCA
InParanoidiP15031
KOiK02013
OMAiCRYAHHL
PhylomeDBiP15031

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P15031-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRTENLTV SYGTDKVLND VSLSLPTGKI TALIGPNGCG KSTLLNCFSR
60 70 80 90 100
LLMPQSGTVF LGDNPINMLS SRQLARRLSL LPQHHLTPEG ITVQELVSYG
110 120 130 140 150
RNPWLSLWGR LSAEDNARVN VAMNQTRINH LAVRRLTELS GGQRQRAFLA
160 170 180 190 200
MVLAQNTPVV LLDEPTTYLD INHQVDLMRL MGELRTQGKT VVAVLHDLNQ
210 220 230 240 250
ASRYCDQLVV MANGHVMAQG TPEEVMTPGL LRTVFSVEAE IHPEPVSGRP

MCLMR
Length:255
Mass (Da):28,191
Last modified:April 1, 1990 - v1
Checksum:i89785C2A91D51FF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26397 Genomic DNA Translation: AAA23765.1
U14003 Genomic DNA Translation: AAA97183.1
U00096 Genomic DNA Translation: AAC77243.1
AP009048 Genomic DNA Translation: BAE78278.1
PIRiJS0115 QRECM3
RefSeqiNP_418707.1, NC_000913.3
WP_000175457.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77243; AAC77243; b4287
BAE78278; BAE78278; BAE78278
GeneIDi948819
KEGGiecj:JW4247
eco:b4287
PATRICifig|1411691.4.peg.2413

Similar proteinsi

Entry informationi

Entry nameiFECE_ECOLI
AccessioniPrimary (citable) accession number: P15031
Secondary accession number(s): Q2M628
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: March 28, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health