Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fe(3+) dicitrate transport ATP-binding protein FecE

Gene

fecE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Part of the binding-protein-dependent transport system for citrate-dependent Fe3+. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 42ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Iron transport, Transport

Keywords - Ligandi

ATP-binding, Iron, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:FECE-MONOMER.
ECOL316407:JW4247-MONOMER.
MetaCyc:FECE-MONOMER.

Protein family/group databases

TCDBi3.A.1.14.1. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Fe(3+) dicitrate transport ATP-binding protein FecE
Alternative name(s):
Iron(III) dicitrate transport ATP-binding protein FecE
Gene namesi
Name:fecE
Ordered Locus Names:b4287, JW4247
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10290. fecE.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000923241 – 255Fe(3+) dicitrate transport ATP-binding protein FecEAdd BLAST255

Proteomic databases

PaxDbiP15031.
PRIDEiP15031.

Expressioni

Inductioni

Induced 1.6-fold by hydroxyurea.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262739. 249 interactors.
IntActiP15031. 2 interactors.
STRINGi511145.b4287.

Structurei

3D structure databases

ProteinModelPortaliP15031.
SMRiP15031.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 238ABC transporterPROSITE-ProRule annotationAdd BLAST236

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105E0A. Bacteria.
COG1120. LUCA.
InParanoidiP15031.
KOiK02013.
OMAiAYSSREL.
PhylomeDBiP15031.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P15031-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRTENLTV SYGTDKVLND VSLSLPTGKI TALIGPNGCG KSTLLNCFSR
60 70 80 90 100
LLMPQSGTVF LGDNPINMLS SRQLARRLSL LPQHHLTPEG ITVQELVSYG
110 120 130 140 150
RNPWLSLWGR LSAEDNARVN VAMNQTRINH LAVRRLTELS GGQRQRAFLA
160 170 180 190 200
MVLAQNTPVV LLDEPTTYLD INHQVDLMRL MGELRTQGKT VVAVLHDLNQ
210 220 230 240 250
ASRYCDQLVV MANGHVMAQG TPEEVMTPGL LRTVFSVEAE IHPEPVSGRP

MCLMR
Length:255
Mass (Da):28,191
Last modified:April 1, 1990 - v1
Checksum:i89785C2A91D51FF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26397 Genomic DNA. Translation: AAA23765.1.
U14003 Genomic DNA. Translation: AAA97183.1.
U00096 Genomic DNA. Translation: AAC77243.1.
AP009048 Genomic DNA. Translation: BAE78278.1.
PIRiJS0115. QRECM3.
RefSeqiNP_418707.1. NC_000913.3.
WP_000175457.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC77243; AAC77243; b4287.
BAE78278; BAE78278; BAE78278.
GeneIDi948819.
KEGGiecj:JW4247.
eco:b4287.
PATRICi32124151. VBIEscCol129921_4419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26397 Genomic DNA. Translation: AAA23765.1.
U14003 Genomic DNA. Translation: AAA97183.1.
U00096 Genomic DNA. Translation: AAC77243.1.
AP009048 Genomic DNA. Translation: BAE78278.1.
PIRiJS0115. QRECM3.
RefSeqiNP_418707.1. NC_000913.3.
WP_000175457.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP15031.
SMRiP15031.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262739. 249 interactors.
IntActiP15031. 2 interactors.
STRINGi511145.b4287.

Protein family/group databases

TCDBi3.A.1.14.1. the atp-binding cassette (abc) superfamily.

Proteomic databases

PaxDbiP15031.
PRIDEiP15031.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77243; AAC77243; b4287.
BAE78278; BAE78278; BAE78278.
GeneIDi948819.
KEGGiecj:JW4247.
eco:b4287.
PATRICi32124151. VBIEscCol129921_4419.

Organism-specific databases

EchoBASEiEB0286.
EcoGeneiEG10290. fecE.

Phylogenomic databases

eggNOGiENOG4105E0A. Bacteria.
COG1120. LUCA.
InParanoidiP15031.
KOiK02013.
OMAiAYSSREL.
PhylomeDBiP15031.

Enzyme and pathway databases

BioCyciEcoCyc:FECE-MONOMER.
ECOL316407:JW4247-MONOMER.
MetaCyc:FECE-MONOMER.

Miscellaneous databases

PROiP15031.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFECE_ECOLI
AccessioniPrimary (citable) accession number: P15031
Secondary accession number(s): Q2M628
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: November 2, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.