P14924 (PPA_ZYMMO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acid phosphatase
EC=3.1.3.2

Gene names

Name:	phoC
Ordered Locus Names:	ZMO0130

Organism

Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) [Complete proteome] [HAMAP]

Taxonomic identifier

264203 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas › Zymomonas mobilis › Zymomonas mobilis subsp. mobilis

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	A phosphate monoester + H2O = an alcohol + phosphate.
Cofactor	Magnesium or zinc. Most active with magnesium.
Subcellular location	Periplasm.
Sequence similarities	Belongs to the class A bacterial acid phosphatase family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	metabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular_function	acid phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 264	236	Acid phosphatase		PRO_0000024003
Experimental info
	Sequence conflict	17	1	I → V in AAA27700. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P14924 [UniParc]. Last modified February 15, 2005. Version 2. Checksum: CAA302345B31A2BD	FASTA	264	29,004
	10 20 30 40 50 60 MIKVPRFICM IALTSGILAS GLSQSVSAHT EKSEPSSTYH FHSDPLLYLA PPPTSGSPLQ 70 80 90 100 110 120 AHDDQTFNST RQLKGSTRWA LATQDADLHL ASVLKDYACA AGMNLDIAQL PHLANLIKRA 130 140 150 160 170 180 LRTEYDDIGR AKNNWNRKRP FVDTDQPICT EKDREGLGKQ GSYPSGHTTI GWSVALILAE 190 200 210 220 230 240 LIPDHAANIL QRGQIFGTSR IVCGAHWFSD VQAGYIMASG EIAALHGDAD FRRDMELARK 250 260 ELEKARTSAH TPDDLLCKIE QSAR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, sequencing, and characterization of the principal acid phosphatase, the phoC+ product, from Zymomonas mobilis." Pond J.L., Eddy C.K., MacKenzie K.F., Conway T., Borecky D.J., Ingram L.O. J. Bacteriol. 171:767-774(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 31821 / ZM4 / CP4.
[2]	"The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4." Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y. , Kang H.L., Lee S.Y., Lee K.J., Kang H.S. Nat. Biotechnol. 23:63-68(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 31821 / ZM4 / CP4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M24141 Genomic DNA. Translation: AAA27700.1. AE008692 Genomic DNA. Translation: AAV88754.1.
PIR	A32044.
RefSeq	YP_161865.1. NC_006526.2.
3D structure databases
ProteinModelPortal	P14924.
ModBase	Search...
Protein-protein interaction databases
STRING	264203.ZMO0130.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAV88754; AAV88754; ZMO0130.
GeneID	3189093.
KEGG	zmo:ZMO0130.
PATRIC	32565612. VBIZymMob102260_0123.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0671.
HOGENOM	HOG000233901.
KO	K09474.
OMA	TPRWELA.
ProtClustDB	CLSK740280.
Family and domain databases
Gene3D	1.20.144.10. 1 hit.
InterPro	IPR011158. Acid_Pase_ClassA. IPR001011. Acid_Pase_classA_bac. IPR018296. Acid_Pase_classA_bac_CS. IPR016118. P_Acid_Pase/Cl_peroxidase_N. IPR000326. P_Acid_Pase_2/haloperoxidase. [Graphical view]
Pfam	PF01569. PAP2. 1 hit. [Graphical view]
PIRSF	PIRSF000897. Acid_Ptase_ClsA. 1 hit.
PRINTS	PR00483. BACPHPHTASE.
SMART	SM00014. acidPPc. 1 hit. [Graphical view]
SUPFAM	SSF48317. AcPase_VanPerase. 1 hit.
PROSITE	PS01157. ACID_PHOSPH_CL_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPA_ZYMMO

Accession

Primary (citable) accession number: P14924
Secondary accession number(s): Q5NRA0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 89 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program