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P14853 (COX3_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Synonyms:COXIII
Encoded onMitochondrion
OrganismGlycine max (Soybean) (Glycine hispida)
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

RNA editing

Edited at positions 102, 130 and 252. Ref.2

Ontologies

Keywords
   Cellular componentMembrane
Mitochondrion
Mitochondrion inner membrane
   Coding sequence diversityRNA editing
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

mitochondrial inner membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Cytochrome c oxidase subunit 3
PRO_0000183854

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane41 – 6121Helical; Potential
Transmembrane84 – 10421Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane162 – 18221Helical; Potential
Transmembrane200 – 22021Helical; Potential
Transmembrane245 – 26521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P14853 [UniParc].

Last modified April 1, 1990. Version 1.
Checksum: 066311899192AB0F

FASTA26529,690
        10         20         30         40         50         60 
MIESQRHSYH LVDPSPWPIS GSLGALATTV GGVMYMHSFQ GGATLLSLGL IFILYTMFVW 

        70         80         90        100        110        120 
WRDVLRESTL EGHHTKVVQL GPRYGSIPFI VSEVMFLFAF FWASSHSSLA PTVEIGGIWP 

       130        140        150        160        170        180 
PLGIWVLDPW EIPFLNTPIL LSSGAAVTWA HHAILAGKEK RAVYALVATV SLALVFTGFQ 

       190        200        210        220        230        240 
GMEYYQAPFT ISDSIYGSTF FLATGFHGFH VIIGTLFLII CGIRQYLGHL TKEHHVGFEA 

       250        260 
AAWYWHFVDV VWLFLFVSIY WWGGI 

« Hide

References

[1]"Cytochrome oxidase subunit III gene from soybean mitochondria."
Grabau E.A., Gengenbach B.G.
Plant Mol. Biol. 13:595-597(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Williams 82.
[2]"Genetic code and phylogenetic origin of oomycetous mitochondria."
Karlovsky P., Fartmann B.
J. Mol. Evol. 34:254-258(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: RNA EDITING.
Strain: cv. Williams 82.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X15131 Genomic DNA. Translation: CAA33227.1. Sequence problems.
PIROTSY3M. S07468.
RefSeqXP_006592610.1. XM_006592547.1.
YP_007516854.1. NC_020455.1.

3D structure databases

ProteinModelPortalP14853.
SMRP14853. Positions 5-263.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100780641.
15308561.
KEGGgmx:100780641.
gmx:100786891.
gmx:15308561.

Phylogenomic databases

KOK02262.

Gene expression databases

GenevestigatorP14853.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_SOYBN
AccessionPrimary (citable) accession number: P14853
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1990
Last sequence update: April 1, 1990
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families