P14850 (2B_PEBV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Protein 2b Alternative name(s): 29.6 kDa protein
Organism	Pea early browning virus
Taxonomic identifier	12294 [NCBI]
Taxonomic lineage	Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Virgaviridae › Tobravirus
Virus host	Phaseolus vulgaris (Kidney bean) (French bean) [TaxID: 3885] Pisum sativum (Garden pea) [TaxID: 3888]

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May function by interacting with a small, flexible domain located at the C-terminus of the CP, forming a bridge between the virus particle and the internal surface of the vector nematode feeding apparatus.
Subcellular location	Virion Ref.3.
Sequence similarities	Belongs to the tobravirus protein 2b family.

Ontologies

Keywords
Cellular component	Virion
Gene Ontology (GO)
Biological_process	transmission of virus Inferred from electronic annotation. Source: InterPro
Cellular_component	virion Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 255	255	Protein 2b		PRO_0000222514

Sequences

	Sequence		Length	Mass (Da)
	P14850 [UniParc]. Last modified April 1, 1990. Version 1. Checksum: 2655D9EC58A87542	FASTA	255	29,559
	10 20 30 40 50 60 MTNWATLWPN DRLFLSDTYQ LIWFDIEADR IEHKHFKAQN SEDISMIPKG FVSFVDNRLP 70 80 90 100 110 120 MCINHKGEVY IRVGSFDTAY YQKFGDLDVS DFDDQVLPPD RDFTFNKVVF GDVPQEQLDN 130 140 150 160 170 180 QIRDLQSEVS ILTSRNVEMN VRENDLLKKV SELEKQIRQS SHNYEKVVED GVVLSYRKAG 190 200 210 220 230 240 GLLNRMVVLN RRLVGQRFVT NQRRWENIIM GSGVHDGSSY MAFNFKESGG SLKVTFDFDK 250 LQNLSPDDLL AMQIA

References

[1]	"Analysis of RNA2 of pea early browning virus strain SP5." Petersen S.G., Lehmbeck J., Borkhardt B. Plant Mol. Biol. 13:735-737(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: SP5.
[2]	"The complete nucleotide sequence of PEBV RNA2 reveals the presence of a novel open reading frame and provides insights into the structure of tobraviral subgenomic promoters." Goulden M.G., Lomonossoff G.P., Davies J.W., Wood K.R. Nucleic Acids Res. 18:4507-4512(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA]. Strain: SP5.
[3]	"Immunogold localization of tobravirus 2b nematode transmission helper protein associated with virus particles." Vellios E., Duncan G., Brown D., MacFarlane S. Virology 300:118-124(2002) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION. Strain: Isolate PaY4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X15883 Genomic RNA. Translation: CAA33893.1. X51828 Genomic RNA. Translation: CAA36126.1.
PIR	S07553.
RefSeq	NP_040352.1. NC_001368.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	962122.
Family and domain databases
InterPro	IPR007935. Tobravirus_2B. [Graphical view]
Pfam	PF05271. Tobravirus_2B. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

2B_PEBV

Accession

Primary (citable) accession number: P14850

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1990
Last sequence update:	April 1, 1990
Last modified:	April 3, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program